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NET39 is a muscle-enriched nuclear envelope transmembrane protein, which regulates initiation of myogenic differentiation via affecting mTOR-IGF-II pathway.
Three muscle-specific (show EIF3K Antibodies) nuclear membrane proteins, NET39, Tmem38A (show TMEM38A Antibodies), and WFS1 (show WFS1 Antibodies), direct specific myogenic genes to the nuclear periphery to facilitate their repression during myogenesis.
The nuclear lamina-associated nuclear envelope transmembrane protein NET39 (Ppapdc3) functions as a negative regulator of myoblast differentiation.
Plays a role as negative regulator of myoblast differentiation, in part through effects on MTOR signaling. Has no detectable enzymatic activity (By similarity).
phosphatidic acid phosphatase type 2 domain containing 3
, probable lipid phosphate phosphatase PPAPDC3
, phosphatidic acid phosphatase type 2 domain-containing protein 3
, nuclear envelope transmembrane protein 39