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anti-Human EIF3F Antibodies:
anti-Mouse (Murine) EIF3F Antibodies:
anti-Rat (Rattus) EIF3F Antibodies:
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Human Polyclonal EIF3F Primary Antibody for IP, ELISA - ABIN129687
Wada, Kato, Okutsu, Miyaki, Suzuki, Yan, Schiaffino, Asahara, Ushida, Akimoto: Translational suppression of atrophic regulators by miR-23a integrates resistance to skeletal muscle atrophy. in The Journal of biological chemistry 2011
The overexpression of eIF3f suppressed Akt (show AKT1 Antibodies) and ERK (show EPHB2 Antibodies) signaling and subsequently depleted CLU (show CLU Antibodies) expression. In addition, eIF3F stabilized p53 (show TP53 Antibodies), which increased the expression of p21 (show CDKN1A Antibodies) and Bax (show BAX Antibodies).
eIF3f/alpha adrenergic receptor interaction
Decreased expression of eukaryotic initiation factor (show EIF4G1 Antibodies) 3f is associated with gastric cancer.
eIF3f may play an important role in recurrence.
findings established a new mechanism of rRNA decay regulation mediated by hnRNP K (show HNRNPK Antibodies)/eIF3f and suggest that the tumor suppressive function of eIF3f may link to impaired rRNA degradation and translation
catalytically inactive forms of eIF3f as well as shRNAs targeting eIF3f repress Notch (show NOTCH1 Antibodies) activation in a coculture assay, showing that eIF3f is a new positive regulator of the Notch (show NOTCH1 Antibodies) pathway
Loss of EIF3F in pancreatic cancer is reported.
demonstrated a statistically significant decrease of the eIF3f gene copy number in melanoma compared with normal tissues with a tumor/normal ratio of 0.52
eIF3f specifically interferes with the 3' end processing of HIV-1 mRNAs
eIF3f may inhibit translation by increasing the binding to the eIF3 (show EIF3A Antibodies) complex during apoptosis.
Data provide evidence that in skeletal muscle cells the degradation of eIF3f suppresses S6K1 (show RPS6KB1 Antibodies) activation by mTOR (show FRAP1 Antibodies) signaling.
Key target that accounts for E3 ubiquitin ligase (show MUL1 Antibodies) MAFbx (atrogin1 (show FBXO32 Antibodies), Fbxo32 (show FBXO32 Antibodies)) function during muscle atrophy; has a major role in skeletal muscle hypertrophy.
MAFbx/Atrogin-1 (show FBXO32 Antibodies) controls the activity of the initiation factor eIF3 (show EIF3A Antibodies)-f in skeletal muscle atrophy by targeting multiple C-terminal lysines.
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome (By similarity).
eukaryotic translation initiation factor 3, subunit F
, eukaryotic translation initiation factor 3 subunit F
, eukaryotic translation initiation factor 3 subunit 5
, Eukaryotic translation initiation factor 3 subunit F
, eukaryotic translation initiation factor 3 subunit 5 epsilon-like protein
, deubiquitinating enzyme eIF3f
, eukaryotic translation initiation factor 3, subunit 5 (epsilon, 47kD)
, eukaryotic translation initiation factor 3, subunit 5 epsilon, 47kDa
, eIF3 p47
, eukaryotic translation initiation factor 3 subunit 5 epsilon
, eukaryotic translation initiation factor 3, subunit 5 (epsilon)