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Browse our Gem (Nuclear Organelle) Associated Protein 2 Proteins (GEMIN2)

Full name:
Gem (Nuclear Organelle) Associated Protein 2 Proteins (GEMIN2)
On www.antibodies-online.com are 6 Gem (Nuclear Organelle) Associated Protein 2 (GEMIN2) Proteins from 4 different suppliers available. Additionally we are shipping Gem (Nuclear Organelle) Associated Protein 2 Antibodies (82) and Gem (Nuclear Organelle) Associated Protein 2 Kits (1) and many more products for this protein. A total of 98 Gem (Nuclear Organelle) Associated Protein 2 products are currently listed.
Synonyms:
1700012N19Rik, HSPC082, SIP-1, Sip1, SIP1-delta, SMADIP1, ZFHX1B
list all proteins Gene Name GeneID UniProt
GEMIN2 8487 O14893
GEMIN2 66603 Q9CQQ4
GEMIN2 84404 Q9QZP1

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Gem (Nuclear Organelle) Associated Protein 2 Proteins (GEMIN2) by Origin

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More Proteins for Gem (Nuclear Organelle) Associated Protein 2 Interaction Partners

Human Gem (Nuclear Organelle) Associated Protein 2 (GEMIN2) interaction partners

  1. low miR-145 expression levels in conjunction with elevated SIP1 expression levels may contribute to cervical cancer development.

  2. Knockdown of ZEB2 can inhibit HOXB8 (show HOXB8 Proteins)-induced migration and invasion capacity, as well as the epithelial-mesenchymal transformation in gastric cancer cells. The results showed that HOXB8 (show HOXB8 Proteins) plays an important role in the development and metastasis of gastric carcinoma

  3. results highlight a feedback loop between miR-203 and ZEB2, which participates in the pathogenesis of lung adenocarcinoma

  4. This is the first study claiming the association of the genetic risks of rs6755392 in the ZEB2 gene with schizophrenia.

  5. Report of the first confirmed cases of Mowat Wilson syndrome in three children with the typical facial features, mental retardation, absent corpus callosum, epilepsy, and Hirschsprung's disease and novel Zeb2 variations on DNA analysis.

  6. Bioinformatics analyses showed that miR-138 targeted the 3'-UTR of ZEB2 mRNA to inhibit its translation. Furthermore, miR-138 overexpression inhibited ZEB2-mediated cell invasion and metastases, while miR-138 depletion increased ZEB2-mediated cell invasion and metastases in BC cells

  7. restoration of ZEB2 effectively reversed the Reduced expression of ZEB2, as well as the suppressive effects of miR200b overexpression on the proliferation.

  8. High ZEB2 expression is associated with clear cell kidney carcinoma.

  9. Results establish that the dowregulation of GADD45G (show GADD45G Proteins)-SIP1 axis may contribute to cellular senescence evasion and HCC (show FAM126A Proteins) development.

  10. restoration of expression of ZEB2 weakened miR (show MLXIP Proteins)-154-mediated suppression of tumor progression. miR (show MLXIP Proteins)-154 functions as a tumor suppressor in HCC (show FAM126A Proteins) by suppressing ZEB2, suggesting that miR (show MLXIP Proteins)-154 may serve as a potential target for HCC (show FAM126A Proteins).

Mouse (Murine) Gem (Nuclear Organelle) Associated Protein 2 (GEMIN2) interaction partners

  1. utilised a targeted screen to identify mRNA associated with SMN (show STMN1 Proteins), Gemin2 and Gemin3 (show DDX20 Proteins) in the cytoplasm of a human neuroblastoma (show ARHGEF16 Proteins) cell line, SHSY5Y

  2. Gene targeting in mice reveals a correlation between defects in the biogenesis of U snRNPs and motoneuron cell death (gemin2; SMN interacting protein 1)

Gem (Nuclear Organelle) Associated Protein 2 (GEMIN2) Protein Profile

Protein Summary

The protein encoded by this gene is a member of the Zfh1 family of 2-handed zinc finger/homeodomain proteins. It is located in the nucleus and functions as a DNA-binding transcriptional repressor that interacts with activated SMADs. Mutations in this gene are associated with Hirschsprung disease/Mowat-Wilson syndrome. Alternatively spliced transcript variants have been found for this gene.

Alternative names and synonyms associated with Gem (Nuclear Organelle) Associated Protein 2 (GEMIN2)

  • gem (nuclear organelle) associated protein 2 (gemin2)
  • gem (nuclear organelle) associated protein 2 (GEMIN2)
  • gem (nuclear organelle) associated protein 2 (Gemin2)
  • zinc finger E-box binding homeobox 2 (ZEB2)
  • 1700012N19Rik protein
  • HSPC082 protein
  • SIP-1 protein
  • Sip1 protein
  • SIP1-delta protein
  • SMADIP1 protein
  • ZFHX1B protein

Protein level used designations for GEMIN2

SMN-interacting protein 1 , Survival of motor neuron protein-interacting protein 1 , component of gems 2 , gem-associated protein 2 , gemin-2 , survival of motor neuron protein interacting protein 1 , SMN interacting protein 1-delta , survival of motor neuron protein-interacting protein 1 , survivor of motor neuron protein interacting protein 1 , SMN interacting protein-1 , SMAD interacting protein 1 , Smad-interacting protein 1 , zinc finger E-box-binding homeobox 2 , zinc finger homeobox 1b

GENE ID SPECIES
494588 Xenopus laevis
8487 Homo sapiens
510259 Bos taurus
66603 Mus musculus
84404 Rattus norvegicus
423336 Gallus gallus
610087 Canis lupus familiaris
9839 Homo sapiens
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