Browse our EFNA4 Proteins (EFNA4)

Full name:
Ephrin A4 Proteins (EFNA4)
On are 25 Ephrin A4 (EFNA4) Proteins from 9 different suppliers available. Additionally we are shipping EFNA4 Antibodies (89) and EFNA4 Kits (16) and many more products for this protein. A total of 138 EFNA4 products are currently listed.
EFL-4, EFL4, EFNA4, Epl4, EPLG4, LERK-4, LERK4
list all proteins Gene Name GeneID UniProt
EFNA4 13639 O08542
EFNA4 310643  
EFNA4 1945 P52798

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EFNA4 Proteins (EFNA4) by Origin

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Top referenced EFNA4 Proteins

  1. Mouse (Murine) EFNA4 Protein expressed in Human Cells - ABIN2008031 : Zhou: The Eph family receptors and ligands. in Pharmacology & therapeutics 1998 (PubMed)
    Show all 4 references for 2008031

  2. Human EFNA4 Protein expressed in HEK-293 Cells - ABIN2181028 : Aasheim, Munthe, Funderud, Smeland, Beiske, Logtenberg: A splice variant of human ephrin-A4 encodes a soluble molecule that is secreted by activated human B lymphocytes. in Blood 2000 (PubMed)
    Show all 2 references for 2181028

More Proteins for EFNA4 Interaction Partners

Mouse (Murine) Ephrin A4 (EFNA4) interaction partners

  1. In a model of temporal lobe epilepsy, Ephrin-A4 and Ephrin-A5 (show EFNA5 Proteins) increase in the hippocampus in a spatiotemporal course.

  2. ephrin-A4 plays an important role in retinal NV and is a potential target against retinal NV. The proangiogenic function of ephrin-A4 may be linked to its crucial role in the VEGF signaling pathway.

  3. Downregulation of the EphA4 (show EPHA4 Proteins) receptor via siRNA transfection reduced the repulsive effect of ephrin-A3 (show EFNA3 Proteins), indicating that EphA4 (show EPHA4 Proteins) mediates at least in part the repulsive effect of ephrin-A3 (show EFNA3 Proteins).

  4. LIM homeodomain proteins control axon pathways topographic projections in the limb through control of EphA receptors and ephrin-A ligands in motor neurons and limb mesenchymal cells.

  5. Ephrin A4 receptor in the thalamus and ephrin A4 in the cerebral cortex control intra-areal topographic mapping of thalamocortical axons.

Human Ephrin A4 (EFNA4) interaction partners

  1. The present study provides evidence that microglia upregulates endothelial ephrin-A3 (show EFNA3 Proteins) and ephrin-A4 to facilitate in vitro angiogenesis of brain endothelial cells, which is mediated by microglia-released TNF-alpha (show TNF Proteins).

  2. The interaction between ephrin-As, Eph (show EPHA1 Proteins) receptors and integrin alpha3 is plausibly important for the crosstalk between Eph (show EPHA1 Proteins) and integrin signalling pathways at the membrane protrusions and in the migration of brain cancer cells.

  3. The cytoplasmic pattern of ephrin A4 could identify a subgroup of primary osteosarcoma patients with a high liability for progression, poor prognosis, and inferior response to chemotherapy.

  4. This provides genetic evidence that Twist1 (show TWIST1 Proteins), Msx2 and Efna4 function together in boundary formation and the pathogenesis of coronal synostosis.

  5. CLL B-cells showed a more heterogeneous Eph (show EPHA1 Proteins)/EFN profile, specially EFNA4, EphB6 (show EPHB6 Proteins) and EphA10 (show EPHA10 Proteins). EphB6 (show EPHB6 Proteins) and EFNA4 were further related with the clinical course of CLL.

  6. EFNA4-EphA2 (show EPHA2 Proteins) interactions are involved in Chronic lymphocytic leukemia cell trafficking between blood and the tissues

EFNA4 Protein Profile

Protein Summary

This gene encodes a member of the ephrin (EPH) family. The ephrins and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events, especially in the nervous system and in erythropoiesis. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. This gene encodes an EFNA class ephrin. Three transcript variants that encode distinct proteins have been identified.

Alternative names and synonyms associated with EFNA4

  • ephrin-A4 (EFNA4)
  • ephrin-A4 (efna4)
  • ephrin A4 (Efna4)
  • EFL-4 protein
  • EFL4 protein
  • EFNA4 protein
  • Epl4 protein
  • EPLG4 protein
  • LERK-4 protein
  • LERK4 protein

Protein level used designations for Ephrin A4 Proteins (EFNA4)

ephrin A4 , ephrin-A4 , EPH-related receptor tyrosine kinase ligand 4 , LERK-4 , eph-related receptor tyrosine kinase ligand 4 , ligand of eph-related kinase 4

469510 Pan troglodytes
490433 Canis lupus familiaris
615879 Bos taurus
100158452 Xenopus laevis
100379980 Xenopus (Silurana) tropicalis
13639 Mus musculus
310643 Rattus norvegicus
1945 Homo sapiens
100154710 Sus scrofa
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