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anti-Human EPH Receptor A2 antibody for Intracellular Flow Cytometry

Recommended EPH Receptor A2 Antibody (supplied by: Log in to see )

Antigen
EPH Receptor A2 (EPHA2) Antibodies
  • ARCC2
  • AW545284
  • CTPA
  • CTPP1
  • CTRCT6
  • Eck
  • ECK
  • epha2
  • EPHA2
  • MGC89505
  • Myk2
  • Sek-2
  • Sek2
Reactivity
Human
199
102
45
10
6
4
3
2
2
2
2
1
Host
Mouse
165
55
6
Clonality
Monoclonal
Conjugate
This EPH Receptor A2 antibody is un-conjugated
11
8
8
8
8
6
2
2
2
2
2
2
2
2
2
Application
Flow Cytometry (FACS), Intracellular Flow Cytometry (ICFC)
168
109
40
32
26
23
18
17
6
6
4
4
1
1
1
Supplier
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Catalog No. ABIN2664953
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Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.0008704084 ABIN2664954 FACS ICFC Mouse IgG2b kappa Log in to see SHM16 5

Top referenced anti-EPH Receptor A2 antibody for Intracellular Flow Cytometry

Similar anti-EPH Receptor A2 Antibodies

Application / Reactivity Human
Cell-ELISA (cELISA) 1 Antibodies
Dot Blot (DB) 18 Antibodies
ELISA 92 Antibodies
Enzyme Immunoassay (EIA) 6 Antibodies
Flow Cytometry (FACS) 23 Antibodies
Functional Studies (Func) 1 Antibodies
Immunochromatography (IC) 4 Antibodies
Immunocytochemistry (ICC) 4 Antibodies
Immunofluorescence (IF) 17 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 23 Antibodies
Immunohistochemistry (IHC) 41 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 34 Antibodies
Immunoprecipitation (IP) 6 Antibodies
Intracellular Flow Cytometry (ICFC) 2 Antibodies
Western Blotting (WB) 151 Antibodies

General

Antigen EPH Receptor A2 (EPHA2) Antibodies
Reactivity Human
(199), (102), (45), (10), (6), (4), (3), (2), (2), (2), (2), (1)
Host Mouse
(165), (55), (6)
Clonality (Clone)
Monoclonal   ( )
Conjugate This EPH Receptor A2 antibody is un-conjugated
(11), (8), (8), (8), (8), (6), (2), (2), (2), (2), (2), (2), (2), (2), (2)
Application Flow Cytometry (FACS), Intracellular Flow Cytometry (ICFC)
(168), (109), (40), (32), (26), (23), (18), (17), (6), (6), (4), (4), (1), (1), (1)
Pubmed 5 references available
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Product Details anti-EPH Receptor A2 Antibody

Target Details EPH Receptor A2 Application Details Handling References for anti-EPH Receptor A2 Antibody (ABIN2664953) Images
Purification The antibody was purified by affinity chromatography.
Clone SHM16
Isotype IgG2b kappa

Target Details EPH Receptor A2

Product Details anti-EPH Receptor A2 Antibody Application Details Handling References for anti-EPH Receptor A2 Antibody (ABIN2664953) Images back to top
Antigen
Alternative Name EphA2 (EPHA2 Antibody Abstract)
Background Ephrin receptor A2 (EphA2), also known as Eck, is a 130 kD type I transmembrane glycoprotein which belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EphA2 is expressed on epithelial cells, keratinocytes, dendritic/Langerhans cells and melanocytes. It has also been observed in breast, cervical, ovarian, prostate, colon, skin and lung cancers. EphA2 is an oncoprotein which is an essential survival factor for many melanomas. EphA2 plays an important role in angiogenesis and tumor neovascularization through interaction with ephrin-A1, -A3, -A4 and -A5.
Research Area Signaling
Pathways RTK Signaling

Application Details

Product Details anti-EPH Receptor A2 Antibody Target Details EPH Receptor A2 Handling References for anti-EPH Receptor A2 Antibody (ABIN2664953) Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-EPH Receptor A2 Antibody Target Details EPH Receptor A2 Application Details References for anti-EPH Receptor A2 Antibody (ABIN2664953) Images back to top
Concentration 0.5 mg/mL
Buffer Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C
Storage Comment The antibody solution should be stored undiluted between 2°C and 8°C.

References for anti-EPH Receptor A2 Antibody (ABIN2664953)

Product Details anti-EPH Receptor A2 Antibody Target Details EPH Receptor A2 Application Details Handling Images back to top
Background publications

Udayakumar, Zhang, Ji, Njauw, Mroz, Tsao: "EphA2 is a critical oncogene in melanoma." in: Oncogene, Vol. 30, Issue 50, pp. 4921-9, 2011

Brantley-Sieders, Zhuang, Hicks, Fang, Hwang, Cates, Coffman, Jackson, Bruckheimer, Muraoka-Cook, Chen: "The receptor tyrosine kinase EphA2 promotes mammary adenocarcinoma tumorigenesis and metastatic progression in mice by amplifying ErbB2 signaling." in: The Journal of clinical investigation, Vol. 118, Issue 1, pp. 64-78, 2008

Pratt, Kinch: "Activation of the EphA2 tyrosine kinase stimulates the MAP/ERK kinase signaling cascade." in: Oncogene, Vol. 21, Issue 50, pp. 7690-9, 2002

Sulman, Tang, Allen, Biegel, Pleasure, Brodeur, Ikegaki: "ECK, a human EPH-related gene, maps to 1p36.1, a common region of alteration in human cancers." in: Genomics, Vol. 40, Issue 2, pp. 371-4, 1997

Pandey, Lazar, Saltiel, Dixit: "Activation of the Eck receptor protein tyrosine kinase stimulates phosphatidylinositol 3-kinase activity." in: The Journal of biological chemistry, Vol. 269, Issue 48, pp. 30154-7, 1994

Images

Product Details anti-EPH Receptor A2 Antibody Target Details EPH Receptor A2 Application Details Handling References for anti-EPH Receptor A2 Antibody (ABIN2664953) back to top
Supplier Images
Flow Cytometry (FACS) image for anti-EPH Receptor A2 antibody (EPHA2) (ABIN2664953) anti-EPH Receptor A2 (EPHA2) antibody