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Browse our FGF19 Proteins (FGF19)

Full name:
Fibroblast Growth Factor 19 Proteins (FGF19)
On www.antibodies-online.com are 35 Fibroblast Growth Factor 19 (FGF19) Proteins from 13 different suppliers available. Additionally we are shipping FGF19 Antibodies (82) and FGF19 Kits (34) and many more products for this protein. A total of 166 FGF19 products are currently listed.
Synonyms:
FGF-19, Fgf15, FGF19
list all proteins Gene Name GeneID UniProt
Mouse FGF19 FGF19 14170 O35622
Rat FGF19 FGF19 170582  
FGF19 9965 O95750

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FGF19 Proteins (FGF19) by Origin

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Top referenced FGF19 Proteins

  1. Human FGF19 Protein expressed in Escherichia coli (E. coli) - ABIN935365 : Borello, Cobos, Long, McWhirter, Murre, Rubenstein: FGF15 promotes neurogenesis and opposes FGF8 function during neocortical development. in Neural development 2008 (PubMed)

  2. Human FGF19 Protein expressed in Escherichia coli (E. coli) - ABIN413241 : Becker-Pauly, Barré, Schilling, Auf dem Keller, Ohler, Broder, Schütte, Kappelhoff, Stöcker, Overall: Proteomic analyses reveal an acidic prime side specificity for the astacin metalloprotease family reflected by physiological substrates. in Molecular & cellular proteomics : MCP 2011 (PubMed)

  3. Human FGF19 Protein expressed in Wheat germ - ABIN1354010 : Uchiyama, Naito, Takagi, Mizushima, Hayashi, Handa, Ishikawa, Yagi, Kokura, Yoshikawa: FGF19 protects colonic epithelial cells against hydrogen peroxide. in Digestion 2011 (PubMed)

More Proteins for FGF19 Interaction Partners

Mouse (Murine) Fibroblast Growth Factor 19 (FGF19) interaction partners

  1. This study reveals SHP (show LAMC1 Proteins) as a global transcriptional partner of SREBP-2 (show SREBF2 Proteins) in regulation of sterol biosynthetic gene networks and provides a potential mechanism for cholesterol-lowering action of FGF19.

  2. Protective effects of farnesoid X receptor (show xpr1 Proteins) on hepatic lipid accumulation are mediated by hepatic FXR (show NR1H4 Proteins) and are independent of intestinal FGF15 signaling.

  3. In mice with humanized livers human hepatocytes do not recognize FGF-15 produced by mouse intestine, resulting in up-regulation of bile acid synthesis enlargement of the bile acid pool, affecting the hepatostat.

  4. Intestinal PPARalpha (show PPARA Proteins)-UDP- Glucuronyltransferases and downstream FXR (show NR1H4 Proteins)-FGF15 signalling play vital roles in control of bile acid homeostasis and the pathological development of colitis.

  5. a direct role of intestinal FGF15/19 in the regulation of SI P450 (show POR Proteins) expression and may have profound implications for the prediction of drug exposure in patients with compromised hepatic P450 (show POR Proteins) function

  6. findings implicate the brain in the antidiabetic action of systemic FGF19 and establish the brain's capacity to rapidly, potently, and selectively increase insulin (show INS Proteins)-independent glucose disposal

  7. Ileal Fibroblast Growth Factor-15 (FGF15) expression was significantly reduced in Asbt (show SLC10A2 Proteins)(-/-)apoE (show APOE Proteins)(-/-) mice and was inversely correlated with expression of hepatic cholesterol 7-hydroxylase (Cyp7a1 (show CYP7A1 Proteins)).

  8. HNF4alpha (show HNF4A Proteins) and LRH-1 (show NR5A2 Proteins) promote active transcription histone marks on the Cyp7a1 (show CYP7A1 Proteins) promoter that are reversed by FGF19 in a SHP (show LAMC1 Proteins)-dependent manner

  9. Total ileal FGF15 expression was elevated almost 20-fold in Ostalpha (show OSTALPHA Proteins)(-/-) mice as a result of increased villus epithelial cell number and ileocyte FGF15 protein expression

  10. generated a variant of FGF19, FGF19-7, that has altered receptor specificity with a strong bias toward FGFR1c

Human Fibroblast Growth Factor 19 (FGF19) interaction partners

  1. FGF19 correlates with severity of liver disease and can potentially serve as an indicator of chronic cholestatic liver injury.

  2. Study shows that FGF19 can be secreted and promotes ovarian cancer progression such as proliferation and invasion by activating FGFR4 (show FGFR4 Proteins).

  3. Suggest a potential connection between gallbladder cholangiocyte-derived FGF19 and bile acid metabolism that could lead to metabolic dysregulation following cholecystectomy.

  4. FGF-19 increment after OGL was positively associated with age, and negatively associated with abnormal glucose regulation and statin treatment

  5. KL methylation is a characteristic of many breast cancer cases . However, the resulting or associated perturbation in FGFR4 (show FGFR4 Proteins) expression, similar to FGF19, could be utilized as a biomarker for poor prognosis

  6. The pathogenesis of intestinal failure associated liver disease is uncertain, we therefore investigated the role of FGF19 and pro-inflammatory cytokines has on this disease state.

  7. In this review, we have reported the altered expression of FGF19 in non-alcoholic fatty liver disease and hepatocellular carcinoma; we find limited information on the role of FGF19 in other liver diseases

  8. In mice with humanized livers, expression of an FGF19 transgene corrects bile acid signaling defects, resulting in normalization of bile acid synthesis, the bile acid pool, and liver size.

  9. The data suggest that FGF19/FGF21 (show FGF21 Proteins) circulating levels and hepatic gene expression of the associated signaling pathway are significantly dysregulated in type 2 diabetes.

  10. Describe a nontumorigenic FGF19 variant, M70, which regulates bile acid metabolism and, through inhibition of bile acid synthesis/reduction of excess hepatic bile acid accumulation, protects mice from cholestatic liver injury.

FGF19 Protein Profile

Protein Summary

The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes including embryonic development cell growth, morphogenesis, tissue repair, tumor growth and invasion. This growth factor is a high affinity, heparin dependent ligand for FGFR4. Expression of this gene was detected only in fetal but not adult brain tissue. Synergistic interaction of the chick homolog and Wnt-8c has been shown to be required for initiation of inner ear development.

Alternative names and synonyms associated with FGF19

  • fibroblast growth factor 19 (LOC100219091)
  • fibroblast growth factor 15 (Fgf15)
  • fibroblast growth factor 19 (Fgf19)
  • fibroblast growth factor 19 (FGF19)
  • fibroblast growth factor 19-like (LOC100518950)
  • fibroblast growth factor 19-like (LOC100358328)
  • FGF-19 protein
  • Fgf15 protein
  • FGF19 protein

Protein level used designations for FGF19

fibroblast growth factor 19 , FGF-15 , fibroblast growth factor 15 , FGF-19

GENE ID SPECIES
100219091 Taeniopygia guttata
14170 Mus musculus
170582 Rattus norvegicus
9965 Homo sapiens
521475 Bos taurus
395394 Gallus gallus
100518950 Sus scrofa
100358328 Oryctolagus cuniculus
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