FGF19 Protein (AA 25-216) (Fc Tag)

Catalog No. ABIN7012994

Product Details

Target: FGF19 (Fibroblast Growth Factor 19 (FGF19))

Protein Type: Recombinant

Protein Characteristics: AA 25-216

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This FGF19 protein is labelled with Fc Tag.

Purpose: Human FGF19 Protein, Fc Tag

Purity: >90 % as determined by SDS-PAGE.

Endotoxin Level: Less than 1.0 EU per μg by the LAL method.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 50 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH 7.5

Storage: -20 °C

Target Details

Target: FGF19 (Fibroblast Growth Factor 19 (FGF19))

Alternative Name: FGF19 (FGF19 Products)

Synonyms: FGF-19 Protein, Fgf15 Protein, fibroblast growth factor 19 Protein, FGF19 Protein, Fgf19 Protein, fgf19 Protein

Background: Fibroblast growth factor (FGF)19 is the first members of a new subfamily of FGFs and could act as hormones. During fetal life, FGF15/19 is involved in organogenesis, affecting the development of the ear, eye, heart, and brain. FGFs-FGFRs are involved in regulation of many biological processes such as embryonic development, cell proliferation, differentiation, and tissue repair. The dysregulation of FGF-FGFR was observed in different types of diseases, disorders, and cancers. Notably, aberrant expression of FGF19/FGFR4 contributes to Hepatocellular Carcinoma progression.

Molecular Weight: 47.9 kDa

Pathways: RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway