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|Antigen||C-Fos Induced Growth Factor (Vascular Endothelial Growth Factor D) (Figf) Antibodies|
|Conjugate||This FIGF antibody is un-conjugated Alternatives|
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
|3 references available|
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Product Details anti-FIGF AntibodyTarget Details FIGF Application Details Handling References for anti-FIGF antibody (ABIN358813) Images
|Specificity||This antibody reacts to VEGFD (VEGF4).|
|Purification||Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS|
|Immunogen||This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human VEGF4.|
Target Details FIGFProduct Details anti-FIGF Antibody Application Details Handling References for anti-FIGF antibody (ABIN358813) Images back to top
|Alternative Name||VEGFD (Figf Antibody Abstract)|
|Background||The protein encoded by this gene is a member of the platelet-derived growth factor/vascular endothelial growth factor (PDGF/VEGF) family and is active in angiogenesis, lymphangiogenesis, and endothelial cell growth. This secreted protein undergoes a complex proteolytic maturation, generating multiple processed forms which bind and activate VEGFR-2 and VEGFR-3 receptors. This protein is structurally and functionally similar to vascular endothelial growth factor C.Synonyms: FIGF, VEGF-D, Vascular endothelial growth factor D, c-Fos-induced growth factor|
|Gene ID||2277, 9606|
|Research Area||Cancer, Angiogenesis, Growth Factors|
Application DetailsProduct Details anti-FIGF Antibody Target Details FIGF Handling References for anti-FIGF antibody (ABIN358813) Images back to top
ELISA: 1/1,000. Western blotting: 1/250 - 1/500. Immunohistochemistry: 1/50 - 1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
|Restrictions||For Research Use only|
HandlingProduct Details anti-FIGF Antibody Target Details FIGF Application Details References for anti-FIGF antibody (ABIN358813) Images back to top
|Buffer||PBS with 0.09 % (W/V) sodium azide|
|Precaution of Use||This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.|
|Handling Advice||Avoid repeated freezing and thawing.|
|Storage||4 °C/-20 °C|
|Storage Comment||Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.|
References for anti-FIGF antibody (ABIN358813)Product Details anti-FIGF Antibody Target Details FIGF Application Details Handling Images back to top
Orlandini, Semboloni, Oliviero: "Beta-catenin inversely regulates vascular endothelial growth factor-D mRNA stability." in: The Journal of biological chemistry, Vol. 278, Issue 45, pp. 44650-6, 2003
McColl, Baldwin, Roufail, Freeman, Moritz, Simpson, Alitalo, Stacker, Achen: "Plasmin activates the lymphangiogenic growth factors VEGF-C and VEGF-D." in: The Journal of experimental medicine, Vol. 198, Issue 6, pp. 863-8, 2003
Rissanen, Markkanen, Gruchala, Heikura, Puranen, Kettunen, Kholová, Kauppinen, Achen, Stacker, Alitalo, Ylä-Herttuala: "VEGF-D is the strongest angiogenic and lymphangiogenic effector among VEGFs delivered into skeletal muscle via adenoviruses." in: Circulation research, Vol. 92, Issue 10, pp. 1098-106, 2003
ImagesProduct Details anti-FIGF Antibody Target Details FIGF Application Details Handling References for anti-FIGF antibody (ABIN358813) back to top