anti-Human HER2 antibody for Dot Blot

Recommended HER2 Antibody (supplied by: Log in to see )

Antigen
V-Erb-B2 erythroblastic Leukemia Viral Oncogene Homolog 2, Neuro/glioblastoma Derived Oncogene Homolog (Avian) (ERBB2) Antibodies
  • CD340
  • HER-2
  • HER-2/neu
  • HER2
  • MLN 19
  • NEU
  • NGL
  • TKR1
  • Erbb-2
  • Neu
  • c-erbB2
  • c-neu
  • mKIAA3023
  • v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog
  • v-erb-b2 avian erythroblastic leukemia viral oncogene 2
  • v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2
  • v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)
  • ERBB2
  • Erbb2
Epitope
pTyr1112
101
95
72
69
62
55
54
48
46
35
26
22
22
21
20
20
20
20
20
20
20
20
20
19
19
19
18
17
15
15
13
13
13
12
11
8
8
8
8
8
7
7
6
6
5
5
4
4
4
4
4
4
3
3
3
3
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human
1373
494
325
36
34
15
13
8
6
5
4
3
3
3
2
1
1
1
1
1
Host
Rabbit
1005
512
30
16
12
5
1
Clonality
Polyclonal
Conjugate
This HER2 antibody is un-conjugated
76
66
59
54
46
41
19
19
12
12
11
10
10
9
8
8
8
8
8
7
7
7
7
7
7
7
7
6
3
2
2
Application
Dot Blot (DB), Western Blotting (WB)
715
602
318
314
309
308
267
132
112
102
89
21
19
18
8
6
6
5
3
3
3
2
1
1
1
1
1
1
1
Options
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Catalog No. ABIN1881408
$ 324.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
28.66777 ABIN1881312 DB IF WB Rabbit pTyr1005 Log in to see Polyclonal 3
28.66777 ABIN1881305 DB WB Rabbit pTyr1248 Log in to see Polyclonal 5
28.66777 ABIN1881313 DB IF WB Rabbit pTyr1196 Log in to see Polyclonal 3
28.66777 ABIN1881304 DB WB Rabbit pTyr1112 Log in to see Polyclonal 5
28.66777 ABIN1539685 DB Rabbit Ig pSer1105 Log in to see Polyclonal
28.66777 ABIN1539721 DB IF Rabbit Ig pThr1172 Log in to see Polyclonal
28.66777 ABIN1539754 DB WB Rabbit Ig pTyr877 Log in to see Polyclonal
28.66777 ABIN1539720 DB IF Rabbit Ig pThr1166 Log in to see Polyclonal
28.66777 ABIN1539785 DB IF WB Rabbit Ig pTyr1127 Log in to see Polyclonal
28.66777 ABIN1539738 DB WB Rabbit Ig pTyr1139 Log in to see Polyclonal
28.66777 ABIN1539689 DB WB Rabbit Ig pSer1151 Log in to see Polyclonal
28.66777 ABIN3029497 DB IF ELISA Rabbit Ig Fraction pThr1172 Log in to see Polyclonal
28.66777 ABIN3029508 DB ELISA WB Rabbit Ig Fraction pTyr877 Log in to see Polyclonal
28.66777 ABIN3029511 DB ELISA WB Rabbit Ig Fraction pSer1151 Log in to see Polyclonal
28.66777 ABIN3029502 DB ELISA WB Rabbit Ig Fraction pTyr1140 Log in to see Polyclonal
28.66777 ABIN3029493 DB IF ELISA WB Rabbit Ig Fraction pTyr1196 Log in to see Polyclonal
28.66777 ABIN3029498 DB IF ELISA WB Rabbit Ig Fraction pTyr1005 Log in to see Polyclonal
28.66777 ABIN3029499 DB ELISA WB Rabbit Ig Fraction pTyr1112 Log in to see Polyclonal
28.66777 ABIN3029500 DB IF ELISA WB Rabbit Ig Fraction pTyr1127 Log in to see Polyclonal
28.66777 ABIN3029501 DB ELISA WB Rabbit Ig Fraction pTyr1139 Log in to see Polyclonal

General

Antigen V-Erb-B2 erythroblastic Leukemia Viral Oncogene Homolog 2, Neuro/glioblastoma Derived Oncogene Homolog (Avian) (ERBB2) Antibodies
Epitope pTyr1112
(101), (95), (72), (69), (62), (55), (54), (48), (46), (35), (26), (22), (22), (21), (20), (20), (20), (20), (20), (20), (20), (20), (20), (19), (19), (19), (18), (17), (15), (15), (13), (13), (13), (12), (11), (8), (8), (8), (8), (8), (7), (7), (6), (6), (5), (5), (4), (4), (4), (4), (4), (4), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human
(1373), (494), (325), (36), (34), (15), (13), (8), (6), (5), (4), (3), (3), (3), (2), (1), (1), (1), (1), (1)
Host Rabbit
(1005), (512), (30), (16), (12), (5), (1)
Clonality (Clone)
Polyclonal   ( )
Conjugate This HER2 antibody is un-conjugated
(76), (66), (59), (54), (46), (41), (19), (19), (12), (12), (11), (10), (10), (9), (8), (8), (8), (8), (8), (7), (7), (7), (7), (7), (7), (7), (7), (6), (3), (2), (2)
Application Dot Blot (DB), Western Blotting (WB)
(715), (602), (318), (314), (309), (308), (267), (132), (112), (102), (89), (21), (19), (18), (8), (6), (6), (5), (3), (3), (3), (2), (1), (1), (1), (1), (1), (1), (1)
Pubmed 5 references available
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Product Details anti-HER2 Antibody

Target Details HER2 Application Details Handling ProductDetails: References for anti-HER2 antibody (ABIN1881408) Images
Purification This antibody is purified through a protein A column, followed by peptide affinity purification. Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Immunogen This HER2 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Y1112 of human HER2.
Clone RB41955

Target Details HER2

Product Details anti-HER2 Antibody Application Details Handling ProductDetails: References for anti-HER2 antibody (ABIN1881408) Images back to top
Antigen
Alternative Name HER2 (ERBB2 Antibody Abstract)
Background ErbB2 is a member of the epidermal growth factor (EGF) receptor family of receptor tyrosine kinases. This protein has no ligand binding domain of its own and therefore cannot bind growth factors. However, it does bind tightly to other ligand-bound EGF receptor family members to form a heterodimer, stabilizing ligand binding and enhancing kinase-mediated activation of downstream signalling pathways, such as those involving mitogen-activated protein kinase and phosphatidylinositol-3 kinase. Amplification and/or overexpression of this gene has been reported in numerous cancers, including breast and ovarian tumors.

Synonyms: Receptor tyrosine-protein kinase erbB-2 [Precursor], p185erbB2, C-erbB-2, NEU proto-oncogene, Tyrosine kinase-type cell surface receptor HER2, MLN 19, ERBB2, HER2, NEU, NGL,
NCBI Accession NP_001005862, NP_004439
UniProt P04626
Pathways RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Skeletal Muscle Fiber Development

Application Details

Product Details anti-HER2 Antibody Target Details HER2 Handling ProductDetails: References for anti-HER2 antibody (ABIN1881408) Images back to top
Application Notes WB: 1:2000,DB: 1:500
Restrictions For Research Use only

Handling

Product Details anti-HER2 Antibody Target Details HER2 Application Details ProductDetails: References for anti-HER2 antibody (ABIN1881408) Images back to top
Format Liquid
Concentration 0.49 mg/mL
Buffer Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Preservative Sodium azide
Precaution of Use WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

ProductDetails: References for anti-HER2 antibody (ABIN1881408)

Product Details anti-HER2 Antibody Target Details HER2 Application Details Handling Images back to top
Product cited in:

Brandt, Mikesch, Simon, Rötger, Kemming, Schier, Sauter, Bürger: "Selective expression of a splice variant of decay-accelerating factor in c-erbB-2-positive mammary carcinoma cells showing increased transendothelial invasiveness." in: Biochemical and biophysical research communications, Vol. 329, Issue 1, pp. 318-23, 2005

Ghatak, Misra, Toole: "Hyaluronan constitutively regulates ErbB2 phosphorylation and signaling complex formation in carcinoma cells." in: The Journal of biological chemistry, Vol. 280, Issue 10, pp. 8875-83, 2005

Provinciali, Re, Donnini, Orlando, Bartozzi, Di Stasio, Smorlesi: "Effect of resveratrol on the development of spontaneous mammary tumors in HER-2/neu transgenic mice." in: International journal of cancer. Journal international du cancer, Vol. 115, Issue 1, pp. 36-45, 2005

Yee, Young, Rosol, Vanbuskirk, Clinton: "Dietary (n-3) polyunsaturated fatty acids inhibit HER-2/neu-induced breast cancer in mice independently of the PPARgamma ligand rosiglitazone." in: The Journal of nutrition, Vol. 135, Issue 5, pp. 983-8, 2005

Beckers, Herrmann, Rieger, Drobyshev, Horsch, Hrabé de Angelis, Seliger: "Identification and validation of novel ERBB2 (HER2, NEU) targets including genes involved in angiogenesis." in: International journal of cancer. Journal international du cancer, Vol. 114, Issue 4, pp. 590-7, 2005

Images

Product Details anti-HER2 Antibody Target Details HER2 Application Details Handling ProductDetails: References for anti-HER2 antibody (ABIN1881408) back to top
Supplier Images
Dot Blot (DB) image for anti-V-Erb-B2 erythroblastic Leukemia Viral Oncogene Homolog 2, Neuro/glioblastoma Derived Oncogene Homolog (Avian) (ERBB2) (pTyr1112) antibody (ABIN1881408) Dot blot analysis of Phospho-HER2-pY1112 Phospho-specific Pab (ABIN1881408) on nitroc...
Western Blotting (WB) image for anti-V-Erb-B2 erythroblastic Leukemia Viral Oncogene Homolog 2, Neuro/glioblastoma Derived Oncogene Homolog (Avian) (ERBB2) (pTyr1112) antibody (ABIN1881408) Dot blot analysis of Phospho-HER2-pY1112 Phospho-specific Pab (ABIN1881408) on nitroc...