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anti-Human HER2 antibody for Dot Blot

Recommended HER2 Antibody (supplied by: Log in to see )

Antigen
V-Erb-B2 erythroblastic Leukemia Viral Oncogene Homolog 2, Neuro/glioblastoma Derived Oncogene Homolog (Avian) (ERBB2) Antibodies
  • c-erbB2
  • c-neu
  • CD340
  • Erbb-2
  • HER-2
  • HER-2/neu
  • HER2
  • mKIAA3023
  • MLN 19
  • NEU
  • Neu
  • NGL
  • TKR1
Epitope
pTyr1196
120
83
64
54
54
53
51
44
37
36
32
29
21
20
20
20
20
19
19
19
19
19
18
18
18
18
15
14
14
14
13
13
13
12
10
10
9
8
8
8
8
7
7
7
7
7
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
5
5
4
4
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human
1322
418
261
24
13
4
3
3
3
3
2
2
1
1
1
Host
Rabbit
968
496
25
18
5
5
Clonality
Polyclonal
Conjugate
This HER2 antibody is un-conjugated
74
65
60
52
45
41
17
17
10
10
9
8
8
8
8
8
8
7
7
7
7
7
7
7
7
7
7
2
2
2
Application
Dot Blot (DB), Immunofluorescence (IF), Western Blotting (WB)
680
574
331
322
301
281
235
174
104
90
86
21
17
6
6
5
5
5
3
3
2
2
1
1
1
1
Supplier
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Catalog No. ABIN1881313
$ 324.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.63784635 ABIN1881312 DB IF WB Rabbit pTyr1005 Log in to see Polyclonal 3
0.63784635 ABIN1881304 DB WB Rabbit pTyr1112 Log in to see Polyclonal 5
0.63784635 ABIN1881408 DB WB Rabbit pTyr1112 Log in to see Polyclonal 5
0.63784635 ABIN1881305 DB WB Rabbit pTyr1248 Log in to see Polyclonal 5
0.63784635 ABIN1539685 DB Rabbit Ig pSer1105 Log in to see Polyclonal
0.63784635 ABIN1539721 DB IF Rabbit Ig pThr1172 Log in to see Polyclonal
0.63784635 ABIN1539754 DB WB Rabbit Ig pTyr877 Log in to see Polyclonal
0.63784635 ABIN1539689 DB WB Rabbit Ig pSer1151 Log in to see Polyclonal
0.63784635 ABIN1539720 DB IF Rabbit Ig pThr1166 Log in to see Polyclonal
0.63784635 ABIN1539785 DB IF WB Rabbit Ig pTyr1127 Log in to see Polyclonal
0.63784635 ABIN1539738 DB WB Rabbit Ig pTyr1139 Log in to see Polyclonal
0.63784635 ABIN2160987 DB IF Rabbit Ig Fraction pThr1172 Log in to see Polyclonal
0.63784635 ABIN2160986 DB IF Rabbit Ig Fraction pThr1166 Log in to see Polyclonal
0.63784635 ABIN2160989 DB IF Rabbit Ig Fraction pThr1127 Log in to see Polyclonal
0.63784635 ABIN2160988 DB Rabbit Ig Fraction pThr1112 Log in to see Polyclonal
0.63784635 ABIN2160984 DB IF Rabbit Ig Fraction Log in to see Polyclonal
0.63784635 ABIN2160985 DB IF Rabbit Ig Fraction Log in to see Polyclonal
0.0008934913 ABIN1944841 DB WB Rabbit Ig pSer1107 Log in to see Polyclonal 3
0.0008934913 ABIN1953047 DB ELISA Alkaline Phosphatase (AP) Rabbit IgG Thr1166, pThr1166 Log in to see Polyclonal
0.0008934913 ABIN1953048 DB ELISA Alkaline Phosphatase (AP) Rabbit IgG Thr1172, pThr1172 Log in to see Polyclonal

Top referenced anti-HER2 antibody for Dot Blot

Similar anti-HER2 Antibodies

Application / Reactivity Human
Cellular Assay (CA) 1 Antibodies
Dot Blot (DB) 192 Antibodies
ELISA 439 Antibodies
ELISA (Capture) 1 Antibodies
Enzyme Immunoassay (EIA) 17 Antibodies
Flow Cytometry (FACS) 275 Antibodies
Functional Studies (Func) 5 Antibodies
Immunoassay (IA) 1 Antibodies
Immunochromatography (IC) 5 Antibodies
Immunocytochemistry (ICC) 86 Antibodies
Immunoelectron Microscopy (IEM) 6 Antibodies
Immunofluorescence (IF) 302 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 90 Antibodies
Immunohistochemistry (IHC) 329 Antibodies
Immunohistochemistry (Acetone-fixed) (IHC (af)) 5 Antibodies
Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp)) 2 Antibodies
Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) 3 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 104 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 235 Antibodies

General

Antigen V-Erb-B2 erythroblastic Leukemia Viral Oncogene Homolog 2, Neuro/glioblastoma Derived Oncogene Homolog (Avian) (ERBB2) Antibodies
Epitope pTyr1196
(120), (83), (64), (54), (54), (53), (51), (44), (37), (36), (32), (29), (21), (20), (20), (20), (20), (19), (19), (19), (19), (19), (18), (18), (18), (18), (15), (14), (14), (14), (13), (13), (13), (12), (10), (10), (9), (8), (8), (8), (8), (7), (7), (7), (7), (7), (6), (6), (6), (6), (6), (6), (6), (6), (6), (6), (6), (6), (6), (6), (6), (5), (5), (4), (4), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human
(1322), (418), (261), (24), (13), (4), (3), (3), (3), (3), (2), (2), (1), (1), (1)
Host Rabbit
(968), (496), (25), (18), (5), (5)
Clonality (Clone)
Polyclonal   ( )
Conjugate This HER2 antibody is un-conjugated
(74), (65), (60), (52), (45), (41), (17), (17), (10), (10), (9), (8), (8), (8), (8), (8), (8), (7), (7), (7), (7), (7), (7), (7), (7), (7), (7), (2), (2), (2)
Application Dot Blot (DB), Immunofluorescence (IF), Western Blotting (WB)
(680), (574), (331), (322), (301), (281), (235), (174), (104), (90), (86), (21), (17), (6), (6), (5), (5), (5), (3), (3), (2), (2), (1), (1), (1), (1)
Pubmed 3 references available
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Product Details anti-HER2 Antibody

Target Details HER2 Application Details Handling References for anti-HER2 Antibody (ABIN1881313) Images
Purification This antibody is purified through a protein A column, followed by peptide affinity purification. Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Immunogen This ERBB2 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Y1196 of human ERBB2.
Clone RB40085

Target Details HER2

Product Details anti-HER2 Antibody Application Details Handling References for anti-HER2 Antibody (ABIN1881313) Images back to top
Antigen
Alternative Name ERBB2 (ERBB2 Antibody Abstract)
Background This gene encodes a member of the epidermal growth factor (EGF) receptor family of receptor tyrosine kinases. This protein has no ligand binding domain of its own and therefore cannot bind growth factors. However, it does bind tightly to other ligand-bound EGF receptor family members to form a heterodimer, stabilizing ligand binding and enhancing kinase-mediated activation of downstream signalling pathways, such as those involving mitogen-activated protein kinase and phosphatidylinositol-3 kinase. Allelic variations at amino acid positions 654 and 655 of isoform a (positions 624 and 625 of isoform b) have been reported, with the most common allele, Ile654/Ile655, shown here. Amplification and/or overexpression of this gene has been reported in numerous cancers, including breast and ovarian tumors. Alternative splicing results in several additional transcript variants, some encoding different isoforms and others that have not been fully characterized.

Synonyms: ERBB2, HER2, MLN19, NEU, NGL, Receptor tyrosine-protein kinase erbB-2, Metastatic lymph node gene 19 protein, Proto-oncogene Neu, Proto-oncogene c-ErbB-2, Tyrosine kinase-type cell surface receptor HER2, p185erbB2, CD_antigen=CD340, Flags: Precursor
NCBI Accession NP_001005862, NP_004439
UniProt P04626
Pathways RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway

Application Details

Product Details anti-HER2 Antibody Target Details HER2 Handling References for anti-HER2 Antibody (ABIN1881313) Images back to top
Application Notes WB: 1:4000,IF: 1:100,DB: 1:500
Restrictions For Research Use only

Handling

Product Details anti-HER2 Antibody Target Details HER2 Application Details References for anti-HER2 Antibody (ABIN1881313) Images back to top
Format Liquid
Concentration 0.35 mg/mL
Buffer Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Preservative Sodium azide
Precaution of Use WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

References for anti-HER2 Antibody (ABIN1881313)

Product Details anti-HER2 Antibody Target Details HER2 Application Details Handling Images back to top
Product cited in:

Lacroix, Leclercq: "Relevance of breast cancer cell lines as models for breast tumours: an update." in: Breast cancer research and treatment, Vol. 83, Issue 3, pp. 249-89, 2004

Levenson, Jordan: "MCF-7: the first hormone-responsive breast cancer cell line." in: Cancer research, Vol. 57, Issue 15, pp. 3071-8, 1997

Soule, Vazguez, Long, Albert, Brennan: "A human cell line from a pleural effusion derived from a breast carcinoma." in: Journal of the National Cancer Institute, Vol. 51, Issue 5, pp. 1409-16, 1974

Images

Product Details anti-HER2 Antibody Target Details HER2 Application Details Handling References for anti-HER2 Antibody (ABIN1881313) back to top
Supplier Images
Dot Blot (DB) image for anti-HER2 antibody (V-Erb-B2 erythroblastic Leukemia Viral Oncogene Homolog 2, Neuro/glioblastoma Derived Oncogene Homolog (Avian)) (pTyr1196) (ABIN1881313) Dot blot analysis of ERBB2 Antibody (Phospho Y1196) Phospho-specific Pab (ABIN1881313...
Immunofluorescence (IF) image for anti-HER2 antibody (V-Erb-B2 erythroblastic Leukemia Viral Oncogene Homolog 2, Neuro/glioblastoma Derived Oncogene Homolog (Avian)) (pTyr1196) (ABIN1881313) Dot blot analysis of ERBB2 Antibody (Phospho Y1196) Phospho-specific Pab (ABIN1881313...
Western Blotting (WB) image for anti-HER2 antibody (V-Erb-B2 erythroblastic Leukemia Viral Oncogene Homolog 2, Neuro/glioblastoma Derived Oncogene Homolog (Avian)) (pTyr1196) (ABIN1881313) Dot blot analysis of ERBB2 Antibody (Phospho Y1196) Phospho-specific Pab (ABIN1881313...