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anti-Human HER2 antibody for Immunohistochemistry (Frozen Sections)

Recommended HER2 Antibody (supplied by: Log in to see )

Antigen
V-Erb-B2 erythroblastic Leukemia Viral Oncogene Homolog 2, Neuro/glioblastoma Derived Oncogene Homolog (Avian) (ERBB2) Antibodies
  • c-erbB2
  • c-neu
  • CD340
  • Erbb-2
  • HER-2
  • HER-2/neu
  • HER2
  • mKIAA3023
  • MLN 19
  • NEU
  • Neu
  • NGL
  • TKR1
Reactivity
Human
1145
407
234
24
12
4
3
3
3
3
2
2
1
1
1
Host
Rabbit
936
351
19
18
5
5
Clonality
Polyclonal
Conjugate
This HER2 antibody is un-conjugated
67
62
53
45
45
41
9
9
8
8
8
8
8
8
8
2
2
1
Application
Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
624
514
323
319
215
181
133
112
90
44
21
17
12
6
6
5
5
5
3
3
2
2
1
1
1
1
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Catalog No. ABIN115291
$ 368.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.00088051456 ABIN115290 IHC (fro) IHC (p) Rabbit Log in to see Polyclonal 1
0.00088051456 ABIN967459 IHC (fro) IHC (p) IP WB Mouse IgG1 AA 1242-1255 Log in to see 3B5 9
0.00088051456 ABIN112219 IHC (fro) IF IHC (p) RIA WB Mouse IgG1 Log in to see CB11 2
0.00088051456 ABIN372478 IHC (fro) IHC (p) IP WB Rabbit IgG AA 1243-1255 Log in to see Polyclonal
0.00088051456 ABIN305740 IHC (fro) IHC (p) IP WB Rabbit IgG AA 1243-1255 Log in to see Polyclonal
0.00088051456 ABIN319888 IHC (fro) Rat IgG2b Log in to see ICR52 2
0.00088051456 ABIN119012 IHC (fro) Rat IgG2b Log in to see ICR52 2
0.00088051456 ABIN119013 FACS IHC (fro) IHC (p) IP WB Rat IgG2a Log in to see ICR55
0.00088051456 ABIN959522 IHC (fro) IHC (p) IP WB Mouse IgG1 Log in to see 3B5
0.00088051456 ABIN180510 Func IHC (fro) IF Mouse IgG1 Extracellular Domain Log in to see N12 3
0.00088051456 ABIN283967 IHC (fro) IHC (p) Rabbit IgG Extracellular Domain Log in to see SP3
0.00088051456 ABIN1101368 IEM IHC (fro) FACS IF IHC (p) IP WB Mouse IgG1 Log in to see 9G6
0.00088051456 ABIN187622 IHC (fro) IHC (p) WB Mouse IgG1 Log in to see CB11
0.00088051456 ABIN319889 FACS IHC (fro) IHC (p) IP WB Rat IgG2a Log in to see ICR55
0.00088051456 ABIN1838013 IHC (fro) IHC (p) Mouse IgG1 Internal Region Log in to see CB11
0.00088051456 ABIN609225 IHC (fro) IHC (p) WB Mouse IgG1 Internal Region Log in to see
0.00088051456 ABIN385331 FACS IHC (fro) IF IP Mouse IgG1 Log in to see 9G6-10
0.00088051456 ABIN956569 IHC (fro) IHC (p) Mouse IgG1 Log in to see CB11
0.00088051456 ABIN576254 IHC (fro) ELISA WB Rabbit IgG pThr686 Log in to see Polyclonal
0.00088051456 ABIN2688859 IHC (f) IHC (fro) FACS IP Mouse IgG1 Log in to see 9G6 7

Top referenced anti-HER2 antibody for Immunohistochemistry (Frozen Sections)

Similar anti-HER2 Antibodies

Application / Reactivity Human
Cellular Assay (CA) 1 Antibodies
Dot Blot (DB) 192 Antibodies
ELISA 379 Antibodies
ELISA (Capture) 1 Antibodies
Enzyme Immunoassay (EIA) 17 Antibodies
Flow Cytometry (FACS) 133 Antibodies
Functional Studies (Func) 5 Antibodies
Immunoassay (IA) 1 Antibodies
Immunochromatography (IC) 5 Antibodies
Immunocytochemistry (ICC) 12 Antibodies
Immunoelectron Microscopy (IEM) 6 Antibodies
Immunofluorescence (IF) 215 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 90 Antibodies
Immunohistochemistry (IHC) 317 Antibodies
Immunohistochemistry (Acetone-fixed) (IHC (af)) 5 Antibodies
Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp)) 2 Antibodies
Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) 3 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 45 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 182 Antibodies

General

Antigen V-Erb-B2 erythroblastic Leukemia Viral Oncogene Homolog 2, Neuro/glioblastoma Derived Oncogene Homolog (Avian) (ERBB2) Antibodies
Reactivity Human
(1145), (407), (234), (24), (12), (4), (3), (3), (3), (3), (2), (2), (1), (1), (1)
Host Rabbit
(936), (351), (19), (18), (5), (5)
Clonality
Polyclonal
Conjugate This HER2 antibody is un-conjugated
(67), (62), (53), (45), (45), (41), (9), (9), (8), (8), (8), (8), (8), (8), (8), (2), (2), (1)
Application Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
(624), (514), (323), (319), (215), (181), (133), (112), (90), (44), (21), (17), (12), (6), (6), (5), (5), (5), (3), (3), (2), (2), (1), (1), (1), (1)
Pubmed 3 references available
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Product Details anti-HER2 Antibody

Target Details HER2 Application Details Handling References for anti-HER2 Antibody (ABIN115291) Images
Specificity This antibody reacts with the c-erbB-2 oncoprotein, a 190 kDa protein.
Cellular Localization: Cell membrane
Purification Purified
Immunogen Keyhole limpet hemocyanin conjugated synthetic human peptide c-erbB-2 oncoprotein.

Target Details HER2

Product Details anti-HER2 Antibody Application Details Handling References for anti-HER2 Antibody (ABIN115291) Images back to top
Antigen
Alternative Name CD340 / ERBB2 / HER2 (ERBB2 Antibody Abstract)
Background The proto-oncogene for c-erbB-2 is located on the human chromosome 17, band 21. It has structural similarities to EGFR. Several studies have indicated that c-erbB-2 may be a good indicator of the prognosis of human carcinomas in the breast, ovary, uterus and gastrointestinal tract.Synonyms: HER-2, MNL19, NEU, NEU proto-oncogene, NGL, Receptor tyrosine-protein kinase erbB-2, Tyrosine kinase-type cell surface receptor HER2, c-erbB-2, p185erbB2
Gene ID 2064
NCBI Accession NP_001005862
UniProt P04626
Pathways RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway

Application Details

Product Details anti-HER2 Antibody Target Details HER2 Handling References for anti-HER2 Antibody (ABIN115291) Images back to top
Application Notes Immunohistochemistry on paraffin embedded sections: diluted of 1: 25-1: 50 in an ABC method (30 minutes at room temperature)Although not required, high temperature treatment may enhance the immunostaining inoverfixed tissues. Recommended Positive Control: Breast carcinoma
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-HER2 Antibody Target Details HER2 Application Details References for anti-HER2 Antibody (ABIN115291) Images back to top
Format Liquid
Buffer containing azide as preservative.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

References for anti-HER2 Antibody (ABIN115291)

Product Details anti-HER2 Antibody Target Details HER2 Application Details Handling Images back to top
Background publications

Wright, Angus, Nicholson, Sainsbury, Cairns, Gullick, Kelly, Harris, Horne: "Expression of c-erbB-2 oncoprotein: a prognostic indicator in human breast cancer." in: Cancer research, Vol. 49, Issue 8, pp. 2087-90, 1989

Fukushige, Matsubara, Yoshida, Sasaki, Suzuki, Semba, Toyoshima, Yamamoto: "Localization of a novel v-erbB-related gene, c-erbB-2, on human chromosome 17 and its amplification in a gastric cancer cell line." in: Molecular and cellular biology, Vol. 6, Issue 3, pp. 955-8, 1986

Schechter, Hung, Vaidyanathan, Weinberg, Yang-Feng, Francke, Ullrich, Coussens: "The neu gene: an erbB-homologous gene distinct from and unlinked to the gene encoding the EGF receptor." in: Science (New York, N.Y.), Vol. 229, Issue 4717, pp. 976-8, 1985

Images

Product Details anti-HER2 Antibody Target Details HER2 Application Details Handling References for anti-HER2 Antibody (ABIN115291) back to top
Supplier Images
Immunohistochemistry (IHC) image for anti-HER2 antibody (V-Erb-B2 erythroblastic Leukemia Viral Oncogene Homolog 2, Neuro/glioblastoma Derived Oncogene Homolog (Avian)) (ABIN115291) Formalin fixed paraffin embedded human breast carcinoma stained with c-erbB-2 antibod...