anti-Human HER2 antibody for Immunohistochemistry (Frozen Sections)

Recommended HER2 Antibody (supplied by: Log in to see )

Antigen
V-Erb-B2 erythroblastic Leukemia Viral Oncogene Homolog 2, Neuro/glioblastoma Derived Oncogene Homolog (Avian) (ERBB2) Antibodies
  • CD340
  • HER-2
  • HER-2/neu
  • HER2
  • MLN 19
  • NEU
  • NGL
  • TKR1
  • Erbb-2
  • Neu
  • c-erbB2
  • c-neu
  • mKIAA3023
  • v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog
  • v-erb-b2 avian erythroblastic leukemia viral oncogene 2
  • v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2
  • v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)
  • ERBB2
  • Erbb2
Reactivity
Human
1386
502
325
36
34
15
13
8
6
5
4
3
3
3
2
1
1
1
1
1
Host
Rabbit
1006
523
38
16
13
5
1
Clonality
Polyclonal
Conjugate
This HER2 antibody is un-conjugated
76
66
59
55
47
41
21
21
14
14
13
12
12
9
8
8
8
8
8
7
7
7
7
7
7
7
7
6
3
2
2
Application
Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
721
602
334
321
309
309
268
134
111
102
91
22
21
19
8
6
6
5
5
3
3
2
1
1
1
1
1
1
1
Supplier
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Catalog No. ABIN115290
$ 621.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN115291 IHC (fro) IHC (p) Rabbit Log in to see Polyclonal 3
1 ABIN967459 IHC (fro) IHC (p) IP WB Mouse IgG1 AA 1242-1255 Log in to see 3B5 9
1 ABIN112219 IHC (fro) IF IHC (p) RIA WB Mouse IgG1 Log in to see CB11 2
1 ABIN305740 IHC (fro) IHC (p) IP WB Rabbit IgG AA 1243-1255 Log in to see Polyclonal
1 ABIN372478 IHC (fro) IHC (p) IP WB Rabbit IgG AA 1243-1255 Log in to see Polyclonal
1 ABIN959522 IHC (fro) IHC (p) IP WB Mouse IgG1 Log in to see 3B5
1 ABIN119012 IHC (fro) Rat IgG2b Log in to see ICR52 2
1 ABIN119013 FACS IHC (fro) IHC (p) IP WB Rat IgG2a Log in to see ICR55
1 ABIN319888 IHC (fro) Rat IgG2b Log in to see ICR52 2
1 ABIN2688859 IHC (f) IHC (fro) FACS IP Mouse IgG1 Log in to see 9G6 7
1 ABIN1101368 IEM IHC (fro) FACS IF IHC (p) IP WB Mouse IgG1 Log in to see 9G6
1 ABIN1734112 IHC (fro) IHC (p) IP WB Rabbit IgG AA 1243-1255 Log in to see Polyclonal
1 ABIN385331 FACS IHC (fro) IF IP Mouse IgG1 Extracellular Domain Log in to see 9G6-10
1 ABIN187622 IHC (fro) IHC (p) WB Mouse IgG1 Log in to see CB11
1 ABIN576254 IHC (fro) ELISA WB Rabbit IgG pThr686 Log in to see Polyclonal
1 ABIN319889 FACS IHC (fro) IHC (p) IP WB Rat IgG2a Log in to see ICR55
1 ABIN2962674 FACS IHC (fro) IHC (p) IP WB Mouse IgG1 C-Term Log in to see 3B5
1 ABIN4309187 ELISA FACS ICC IF IHC (fro) WB DyLight 680 Mouse IgG2a kappa Log in to see HRB2-258
1 ABIN4309181 ELISA FACS ICC IF IHC (fro) WB Alexa Fluor 488 Mouse IgG2a kappa Log in to see HRB2-258
1 ABIN4309193 ELISA FACS ICC IF IHC (fro) WB DyLight 550 Mouse IgG2a kappa Log in to see HRB2-258

General

Antigen V-Erb-B2 erythroblastic Leukemia Viral Oncogene Homolog 2, Neuro/glioblastoma Derived Oncogene Homolog (Avian) (ERBB2) Antibodies
Reactivity Human
(1386), (502), (325), (36), (34), (15), (13), (8), (6), (5), (4), (3), (3), (3), (2), (1), (1), (1), (1), (1)
Host Rabbit
(1006), (523), (38), (16), (13), (5), (1)
Clonality
Polyclonal
Conjugate This HER2 antibody is un-conjugated
(76), (66), (59), (55), (47), (41), (21), (21), (14), (14), (13), (12), (12), (9), (8), (8), (8), (8), (8), (7), (7), (7), (7), (7), (7), (7), (7), (6), (3), (2), (2)
Application Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
(721), (602), (334), (321), (309), (309), (268), (134), (111), (102), (91), (22), (21), (19), (8), (6), (6), (5), (5), (3), (3), (2), (1), (1), (1), (1), (1), (1), (1)
Pubmed 1 reference available
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Product Details anti-HER2 Antibody

Target Details HER2 Application Details Handling References for anti-HER2 antibody (ABIN115290) Images
Specificity This antibody reacts with the c-erbB-2 oncoprotein, a 190 kDa protein.
Cellular Localization: Cell membrane
Purification Purified
Immunogen Keyhole limpet hemocyanin conjugated synthetic human peptide c-erbB-2 oncoprotein.

Target Details HER2

Product Details anti-HER2 Antibody Application Details Handling References for anti-HER2 antibody (ABIN115290) Images back to top
Antigen
Alternative Name CD340 / ERBB2 / HER2 (ERBB2 Antibody Abstract)
Background The proto-oncogene for c-erbB-2 is located on the human chromosome 17, band 21. It has structural similarities to EGFR. Several studies have indicated that c-erbB-2 may be a good indicator of the prognosis of human carcinomas in the breast, ovary, uterus and gastrointestinal tract.Synonyms: HER-2, MNL19, NEU, NEU proto-oncogene, NGL, Receptor tyrosine-protein kinase erbB-2, Tyrosine kinase-type cell surface receptor HER2, c-erbB-2, p185erbB2
Gene ID 2064
NCBI Accession NP_001005862
UniProt P04626
Pathways RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Skeletal Muscle Fiber Development

Application Details

Product Details anti-HER2 Antibody Target Details HER2 Handling References for anti-HER2 antibody (ABIN115290) Images back to top
Application Notes Immunohistochemistry on paraffin embedded sections: diluted of 1: 25-1: 50 in an ABC method (30 minutes at room temperature)Although not required, high temperature treatment may enhance the immunostaining inoverfixed tissues. Recommended Positive Control: Breast carcinoma
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-HER2 Antibody Target Details HER2 Application Details References for anti-HER2 antibody (ABIN115290) Images back to top
Format Liquid
Buffer containing azide as preservative.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

References for anti-HER2 antibody (ABIN115290)

Product Details anti-HER2 Antibody Target Details HER2 Application Details Handling Images back to top
Background publications

Wright, Angus, Nicholson, Sainsbury, Cairns, Gullick, Kelly, Harris, Horne: "Expression of c-erbB-2 oncoprotein: a prognostic indicator in human breast cancer." in: Cancer research, Vol. 49, Issue 8, pp. 2087-90, 1989

Images

Product Details anti-HER2 Antibody Target Details HER2 Application Details Handling References for anti-HER2 antibody (ABIN115290) back to top
Supplier Images
Immunohistochemistry (IHC) image for anti-V-Erb-B2 erythroblastic Leukemia Viral Oncogene Homolog 2, Neuro/glioblastoma Derived Oncogene Homolog (Avian) (ERBB2) antibody (ABIN115290) Formalin fixed paraffin embedded human breast carcinoma stained with c-erbB-2 antibod...