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anti-Rhesus Monkey HER2 antibody for ELISA

Recommended HER2 Antibody (supplied by: Log in to see )

Antigen
V-Erb-B2 erythroblastic Leukemia Viral Oncogene Homolog 2, Neuro/glioblastoma Derived Oncogene Homolog (Avian) (ERBB2) Antibodies
  • c-erbB2
  • c-neu
  • CD340
  • Erbb-2
  • HER-2
  • HER-2/neu
  • HER2
  • mKIAA3023
  • MLN 19
  • NEU
  • Neu
  • NGL
  • TKR1
Epitope
AA 1-652
116
84
66
56
53
51
49
45
44
35
33
29
23
20
20
20
20
19
19
19
19
19
19
18
18
18
16
16
14
14
14
13
12
12
12
10
9
9
8
8
7
7
7
7
7
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
5
5
4
4
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Rhesus Monkey
1328
424
261
24
13
4
3
3
3
2
2
2
1
1
1
Host
Mouse
966
501
29
17
8
5
Clonality
Monoclonal
Conjugate
This HER2 antibody is un-conjugated
74
65
60
54
45
41
18
18
17
10
10
9
9
8
8
8
8
8
7
7
7
7
7
7
7
7
3
2
2
2
Application
ELISA
680
576
334
323
297
291
228
169
100
97
84
21
17
6
6
5
5
5
3
3
3
2
2
1
1
1
Supplier
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Catalog No. ABIN2001787
$ 218.90
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.001221279 ABIN2001789 ELISA Rabbit IgG AA 1-652 Log in to see Polyclonal
0.001221279 ABIN2692072 ELISA Rabbit Log in to see Polyclonal

Similar anti-HER2 Antibodies

Application / Reactivity Rhesus Monkey
ELISA 3 Antibodies

General

Antigen V-Erb-B2 erythroblastic Leukemia Viral Oncogene Homolog 2, Neuro/glioblastoma Derived Oncogene Homolog (Avian) (ERBB2) Antibodies
Epitope AA 1-652
(116), (84), (66), (56), (53), (51), (49), (45), (44), (35), (33), (29), (23), (20), (20), (20), (20), (19), (19), (19), (19), (19), (19), (18), (18), (18), (16), (16), (14), (14), (14), (13), (12), (12), (12), (10), (9), (9), (8), (8), (7), (7), (7), (7), (7), (6), (6), (6), (6), (6), (6), (6), (6), (6), (6), (6), (6), (6), (6), (6), (6), (5), (5), (4), (4), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Rhesus Monkey
(1328), (424), (261), (24), (13), (4), (3), (3), (3), (2), (2), (2), (1), (1), (1)
Host Mouse
(966), (501), (29), (17), (8), (5)
Clonality (Clone)
Monoclonal   ( )
Conjugate This HER2 antibody is un-conjugated
(74), (65), (60), (54), (45), (41), (18), (18), (17), (10), (10), (9), (9), (8), (8), (8), (8), (8), (7), (7), (7), (7), (7), (7), (7), (7), (3), (2), (2), (2)
Application ELISA
(680), (576), (334), (323), (297), (291), (228), (169), (100), (97), (84), (21), (17), (6), (6), (5), (5), (5), (3), (3), (3), (2), (2), (1), (1), (1)
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Product Details anti-HER2 Antibody

Target Details HER2 Application Details Handling Images
Specificity Rhesus HER2 / ErbB2
Cross-Reactivity (Details) Has cross-reactivity in ELISA with Human ErbB2 No cross-reactivity in ELISA with Human EGFR Human ERBB3 Human ERBB4 Human cell lysate (293 cell line)
Sensitivity 0.0195 ng/well
Characteristics This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Rhesus HER2 / ErbB2 ( XP_001090430.1, Met 1-Thr 652). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
Sterility 0.2 μm filtered
Clone 10A7F7
Isotype IgG1

Target Details HER2

Product Details anti-HER2 Antibody Application Details Handling Images back to top
Antigen
Alternative Name ERBB2 (ERBB2 Antibody Abstract)
Background Human epidermal growth factor receptor 2 (HER2), also known as ErbB2, NEU, and CD340, is a type I membrane glycoprotein, and belongs to the epidermal growth factor (EGF) receptor family. HER2 protein cannot bind growth factors due to the lacking of ligand binding domain of its own and autoinhibited constitutively. However, HER2 forms a heterodimer with other ligand-bound EGF receptor family members, therefore stabilizes ligand binding and enhances kinase-mediated activation of downstream molecules. HER2 plays a key role in development, cell proliferation and differentiation. HER2 gene has been reported to associate with malignancy and a poor prognosis in numerous carcinomas, including breast, prostate, ovarian, lung cancers and so on.
NCBI Accession XP_001090430.1
Pathways RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway

Application Details

Product Details anti-HER2 Antibody Target Details HER2 Handling Images back to top
Application Notes ELISA ELISA: 0.5-1 μg/mL This antibody can be used at 0.5-1 μg/mL with the appropriate secondary reagents to detect Rhesus ErbB2. The detection limit for Rhesus ErbB2 is approximately 0.0195 ng/well.
Restrictions For Research Use only

Handling

Product Details anti-HER2 Antibody Target Details HER2 Application Details Images back to top
Buffer PBS with 5% trehalose
Preservative Without preservative
Handling Advice Avoid repeated freeze-thaw cycles.
Storage 4 °C/-20 °C/-80 °C
Storage Comment This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -70°C. Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly.
Expiry Date 12 months