anti-Rhesus Monkey HER2 antibody for ELISA

Recommended HER2 Antibody (supplied by: Log in to see )

Antigen
V-Erb-B2 erythroblastic Leukemia Viral Oncogene Homolog 2, Neuro/glioblastoma Derived Oncogene Homolog (Avian) (ERBB2) Antibodies
  • CD340
  • HER-2
  • HER-2/neu
  • HER2
  • MLN 19
  • NEU
  • NGL
  • TKR1
  • Erbb-2
  • Neu
  • c-erbB2
  • c-neu
  • mKIAA3023
  • v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog
  • v-erb-b2 avian erythroblastic leukemia viral oncogene 2
  • v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2
  • v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)
  • ERBB2
  • Erbb2
Epitope
AA 1-652
101
95
72
69
61
58
55
55
48
35
26
22
21
21
21
20
20
20
20
20
20
20
20
20
19
19
19
17
17
15
15
13
13
12
11
8
8
8
8
8
7
7
6
6
5
5
5
4
4
4
4
4
4
3
3
3
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Rhesus Monkey
1387
502
325
36
34
15
13
8
6
5
4
3
3
2
2
1
1
1
1
1
Host
Mouse
1007
522
38
16
13
5
1
Clonality
Monoclonal
Conjugate
This HER2 antibody is un-conjugated
76
66
59
55
47
41
21
21
14
14
13
12
12
9
8
8
8
8
8
7
7
7
7
7
7
7
7
6
3
2
2
Application
ELISA
721
601
334
321
309
309
269
134
112
102
91
22
21
19
8
6
6
5
5
3
3
2
1
1
1
1
1
1
1
Supplier
Log in to see
Supplier Product No.
Log in to see
Request

Get this product for free

Submit your validation data for this product and get a full refund. I want to validate this product

Learn more

Catalog No. ABIN2001787
$ 218.90
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN2001789 ELISA Rabbit IgG AA 1-652 Log in to see Polyclonal
1 ABIN2692072 ELISA Rabbit IgG AA 1-652 Log in to see Polyclonal

General

Antigen V-Erb-B2 erythroblastic Leukemia Viral Oncogene Homolog 2, Neuro/glioblastoma Derived Oncogene Homolog (Avian) (ERBB2) Antibodies
Epitope AA 1-652
(101), (95), (72), (69), (61), (58), (55), (55), (48), (35), (26), (22), (21), (21), (21), (20), (20), (20), (20), (20), (20), (20), (20), (20), (19), (19), (19), (17), (17), (15), (15), (13), (13), (12), (11), (8), (8), (8), (8), (8), (7), (7), (6), (6), (5), (5), (5), (4), (4), (4), (4), (4), (4), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Rhesus Monkey
(1387), (502), (325), (36), (34), (15), (13), (8), (6), (5), (4), (3), (3), (2), (2), (1), (1), (1), (1), (1)
Host Mouse
(1007), (522), (38), (16), (13), (5), (1)
Clonality (Clone)
Monoclonal   ( )
Conjugate This HER2 antibody is un-conjugated
(76), (66), (59), (55), (47), (41), (21), (21), (14), (14), (13), (12), (12), (9), (8), (8), (8), (8), (8), (7), (7), (7), (7), (7), (7), (7), (7), (6), (3), (2), (2)
Application ELISA
(721), (601), (334), (321), (309), (309), (269), (134), (112), (102), (91), (22), (21), (19), (8), (6), (6), (5), (5), (3), (3), (2), (1), (1), (1), (1), (1), (1), (1)
Supplier Log in to see

Product Details anti-HER2 Antibody

Target Details HER2 Application Details Handling Images
Specificity Rhesus HER2 / ErbB2
Has cross-reactivity in ELISA with
Human ErbB2
No cross-reactivity in ELISA with
Human EGFR
Human ERBB3
Human ERBB4
Human cell lysate (293 cell line)
Cross-Reactivity Human
No Cross-Reactivity Human
Characteristics This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Rhesus HER2 / ErbB2 (ABIN2009728 XP_001090430.1, Met 1-Thr 652,. The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
Purification purified by Protein A affinity chromatography
Sterility 0.2 μm filtered
Immunogen Recombinant Rhesus HER2 / ErbB2 protein (ABIN2009728)
Clone 10A7F7
Isotype IgG1

Target Details HER2

Product Details anti-HER2 Antibody Application Details Handling Images back to top
Antigen
Alternative Name ERBB2 (ERBB2 Antibody Abstract)
Background Human epidermal growth factor receptor 2 (HER2), also known as ErbB2, NEU, and CD340, is a type I membrane glycoprotein, and belongs to the epidermal growth factor (EGF) receptor family. HER2 protein cannot bind growth factors due to the lacking of ligand binding domain of its own and autoinhibited constitutively. However, HER2 forms a heterodimer with other ligand-bound EGF receptor family members, therefore stabilizes ligand binding and enhances kinase-mediated activation of downstream molecules. HER2 plays a key role in development, cell proliferation and differentiation. HER2 gene has been reported to associate with malignancy and a poor prognosis in numerous carcinomas, including breast, prostate, ovarian, lung cancers and so on.
NCBI Accession XP_001090430.1
Pathways RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Skeletal Muscle Fiber Development

Application Details

Product Details anti-HER2 Antibody Target Details HER2 Handling Images back to top
Application Notes ELISA: 0.5-1 μg/mL
This antibody can be used at 0.5-1 μg/mL with the appropriate secondary reagents to detect Rhesus ErbB2. The detection limit for Rhesus ErbB2 is approximately 0.0195 ng/well.
Restrictions For Research Use only

Handling

Product Details anti-HER2 Antibody Target Details HER2 Application Details Images back to top
Format Liquid
Buffer 0.2 μm filtered solution in PBS with 5 % trehalose
Preservative Without preservative
Handling Advice Avoid repeated freeze-thaw cycles.
Storage 4 °C,-20 °C,-80 °C
Storage Comment This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free.
Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
Expiry Date 12 months