anti-Human IGF1R antibody for Fluorescence Microscopy

Recommended IGF1R Antibody (supplied by: Log in to see )

Antigen
Insulin-Like Growth Factor 1 Receptor (IGF1R) Antibodies
  • CD221
  • IGFIR
  • IGFR
  • JTK13
  • IGFIRC
  • IGFR1
  • IGF-1R
  • IGF1R
  • DKFZp469I0618
  • igf-1r
  • xIGF-1R
  • xIGFR
  • xigf1r
  • A330103N21Rik
  • D930020L01
  • hyft
  • igf-ir
  • insulin-like growth factor 1 receptor
  • insulin-like growth factor I receptor
  • IGF1R
  • Igf1r
  • igf1r
  • LOC780503
  • igf-ir
Reactivity
Human
492
249
237
18
15
11
7
7
6
5
5
5
2
2
1
Host
Mouse
365
123
2
2
Clonality
Monoclonal
Conjugate
This IGF1R antibody is un-conjugated
20
18
16
15
9
9
8
8
8
8
8
8
8
8
8
7
6
2
Application
Fluorescence Microscopy (FM), Flow Cytometry (FACS)
311
117
104
103
88
79
48
40
8
6
6
4
3
2
2
1
1
1
1
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Catalog No. ABIN967487
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General

Antigen Insulin-Like Growth Factor 1 Receptor (IGF1R) Antibodies
Reactivity Human
(492), (249), (237), (18), (15), (11), (7), (7), (6), (5), (5), (5), (2), (2), (1)
Host Mouse
(365), (123), (2), (2)
Clonality (Clone)
Monoclonal   ( )
Conjugate This IGF1R antibody is un-conjugated
(20), (18), (16), (15), (9), (9), (8), (8), (8), (8), (8), (8), (8), (8), (8), (7), (6), (2)
Application Fluorescence Microscopy (FM), Flow Cytometry (FACS)
(311), (117), (104), (103), (88), (79), (48), (40), (8), (6), (6), (4), (3), (2), (2), (1), (1), (1), (1)
Pubmed 3 references available
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Product Details anti-IGF1R Antibody

Target Details IGF1R Application Details Handling References for anti-IGF1R antibody (ABIN967487) Images
Brand BD Pharmingen™
Characteristics 1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Please refer to us for technical protocols.
3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
Purification The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
Clone 1H7
Isotype IgG1, kappa

Target Details IGF1R

Product Details anti-IGF1R Antibody Application Details Handling References for anti-IGF1R antibody (ABIN967487) Images back to top
Antigen
Alternative Name CD221 (IGF1R Antibody Abstract)
Background Reacts with human insulin-like growth factor-I (IGF-I) receptor alpha subunit (135 kDa). IGF-IRalpha is a glycoprotein complex composed of two extracellular alpha subunits and two transmembrane beta subunits. The transmembrane subunits play a role in tyrosine phosphorylation of several intracellular signaling proteins. IGF-IRalpha is structurally and functionally similar to insulin receptor and is expressed on a variety of human hematopoietic and non-hematopoietic cells. It mediates the effects of IGF-I and IGF-II on cellular growth. 1H7 does not cross react with human insulin receptor and it can block IGF-I or IGF-II stimulated cell growth. This antibody is routinely tested by flow cytometric analysis.
Synonyms: IGF-I Receptor alpha
Pathways RTK Signaling, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Autophagy

Application Details

Product Details anti-IGF1R Antibody Target Details IGF1R Handling References for anti-IGF1R antibody (ABIN967487) Images back to top
Application Notes This product is routinely tested on peripheral blood granulocytes. The histogram is an example of the expected reactivity.
Restrictions For Research Use only

Handling

Product Details anti-IGF1R Antibody Target Details IGF1R Application Details References for anti-IGF1R antibody (ABIN967487) Images back to top
Format Liquid
Concentration 0.5 mg/mL
Buffer Aqueous buffered solution containing ≤0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C
Storage Comment Store undiluted at 4° C.

References for anti-IGF1R antibody (ABIN967487)

Product Details anti-IGF1R Antibody Target Details IGF1R Application Details Handling Images back to top
Product cited in:

Kooijman, Scholtens, Rijkers, Zegers: "Differential expression of type I insulin-like growth factor receptors in different stages of human T cells." in: European journal of immunology, Vol. 25, Issue 4, pp. 931-5, 1995

Li, Kato, Paz, Kasuya, Fujita-Yamaguchi: "Two new monoclonal antibodies against the alpha subunit of the human insulin-like growth factor-I receptor." in: Biochemical and biophysical research communications, Vol. 196, Issue 1, pp. 92-8, 1993

Xiong, Kasuya, Li, Kato, Fujita-Yamaguchi: "Growth-stimulatory monoclonal antibodies against human insulin-like growth factor I receptor." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 89, Issue 12, pp. 5356-60, 1992

Images

Product Details anti-IGF1R Antibody Target Details IGF1R Application Details Handling References for anti-IGF1R antibody (ABIN967487) back to top
Supplier Images
Flow Cytometry (FACS) image for anti-Insulin-Like Growth Factor 1 Receptor (IGF1R) antibody (ABIN967487) Profile of peripheral blood granulocytes analyzed on a FACScan (BDIS, San Jose, CA)