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|Application / Reactivity||Human||Mouse (Murine)||Rat (Rattus)|
|Western Blotting (WB)||55 Antibodies||23 Antibodies||18 Antibodies|
|Immunoprecipitation (IP)||1 Antibodies|
|Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))||2 Antibodies||1 Antibodies|
|Immunohistochemistry (IHC)||2 Antibodies||3 Antibodies|
|Immunohistochemistry (Frozen Sections) (IHC (fro))||2 Antibodies||1 Antibodies|
|Immunofluorescence (IF)||6 Antibodies||1 Antibodies|
|Immunocytochemistry (ICC)||3 Antibodies||2 Antibodies||1 Antibodies|
|Flow Cytometry (FACS)||10 Antibodies||4 Antibodies|
|Antigen||Interleukin 34 (IL34) Antibodies|
|Reactivity||Human, Mouse (Murine), Rat (Rattus) Alternatives|
|Conjugate||This IL34 antibody is un-conjugated Alternatives|
Enzyme Immunoassay (EIA), Western Blotting (WB)
|1 reference available|
|Supplier||Log in to see|
Product Details anti-IL34 AntibodyTarget Details IL34 Application Details Handling References for anti-IL34 Antibody (ABIN500016) Images
|Specificity||This antibody reacts to IL-34.|
|Cross-Reactivity (Details)||Species reactivity (tested):Human brain tissue.|
|Purification||Affinity chromatography purified via peptide column|
|Immunogen||IL-34 antibody was raised against a 16 amino acid peptide from near the amino terminus of human IL-34.|
Target Details IL34Product Details anti-IL34 Antibody Application Details Handling References for anti-IL34 Antibody (ABIN500016) Images back to top
|Alternative Name||Interleukin-34 / IL34 (IL34 Antibody Abstract)|
|Background||Interleukin-34 (IL-34) was identified through a functional screening of a library of secreted proteins after transfection of an embryonic kidney cell line with recombinant cDNAs. Flow cytometry and monocyte viability assays demonstrated increased survival and/or proliferation of monocytes induced by IL-34 and specific binding of IL-34 to CD14+ monocytes. IL-34 is a second ligand to the colony stimulating factor (CSF)-1 receptor in addition to CSF1. Like CSF1, IL-34 stimulates phosphorylation of ERK1 and ERK2 in human monocytes and induces differentiation of bone marrow cells into macrophages. Despite its predicted molecular weight, IL-34 will often run at higher molecular weight in SDS-PAGE.Synonyms: C16orf77, IL-34|
Application DetailsProduct Details anti-IL34 Antibody Target Details IL34 Handling References for anti-IL34 Antibody (ABIN500016) Images back to top
ELISA. Western Blot: 0.25 - 0.5 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
|Restrictions||For Research Use only|
HandlingProduct Details anti-IL34 Antibody Target Details IL34 Application Details References for anti-IL34 Antibody (ABIN500016) Images back to top
|Buffer||PBS containing 0.02 % sodium azide.|
|Precaution of Use||This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.|
References for anti-IL34 Antibody (ABIN500016)Product Details anti-IL34 Antibody Target Details IL34 Application Details Handling Images back to top
Lin, Lee, Hestir et al.: "Discovery of a cytokine and its receptor by functional screening of the extracellular proteome." in: Science (New York, N.Y.), Vol. 320, Issue 5877, pp. 807-11, 2008 (PubMed).
ImagesProduct Details anti-IL34 Antibody Target Details IL34 Application Details Handling References for anti-IL34 Antibody (ABIN500016) back to top