IL-34 antibody

Catalog No. ABIN7074359

Product Details anti-IL-34 Antibody

Target: IL-34 (IL34) (Interleukin 34 (IL34))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IL-34 antibody is un-conjugated

Application: Immunohistochemistry (IHC), Immunofluorescence (IF)

Cross-Reactivity: Rat

Purification: Affinity purification

Immunogen: Recombinant protein corresponding to Mouse IL-34

Application Details

Application Notes: IHC/IF (M,R) 1:500-1:1500

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details for IL-34

Target: IL-34 (IL34) (Interleukin 34 (IL34))

Alternative Name: IL-34 (IL34 Products)

Synonyms: C16orf77 antibody, IL-34 antibody, 2010004A03Rik antibody, AI593503 antibody, C18H16ORF77 antibody, interleukin 34 antibody, IL34 antibody, Il34 antibody

Background: IL-34 is secreted as a dimeric protein and currently belongs to no known cytokine family. It signals via the M-CSF Receptor, also known as CSF-1R and CD115, which is shared with M-CSF. IL-34 has no amino acid sequence homology to M-CSF, but they exhibit similarities in secondary structure and share overlapping functions. IL-34 has been shown to promote myeloid survival, proliferation, and differentiation, and to play a role in osteoclast formation. IL-34 expression has been detected in various tissues and is most abundant in the spleen.

Gene ID: 76527

NCBI Accession: NP_001128572

UniProt: Q8R1R4

Pathways: RTK Signaling