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|Antigen||Insulin Receptor-Related Receptor (INSRR) Antibodies|
|Reactivity||Human, Mouse (Murine), Rat (Rattus) Alternatives|
|Conjugate||This INSRR antibody is conjugated to Alexa Fluor 594 Alternatives|
Immunofluorescence (Paraffin-embedded Sections) (IF (p))
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Product Details anti-INSRR AntibodyTarget Details INSRR Application Details Handling Images
|Purification||Purified by Protein A.|
|Immunogen||KLH conjugated synthetic peptide derived from human Insulin receptor-related protein beta chain|
Target Details INSRRProduct Details anti-INSRR Antibody Application Details Handling Images back to top
|Alternative Name||INSRR (INSRR Antibody Abstract)|
The insulin receptor related receptor (IRR) is a heterotetrameric transmembrane receptor composed of two alpha and 2 beta chains linked by disulfide bonds. The alpha chains contribute to the formation of the ligand-binding domain, while the beta chains carry the kinase domain. Member of the insulin RTK family, IRR shares high homology with the insulin (IR) and the insulin-like growth factor-1 receptor (IGF-1R), but doesnâ€™t bind any of IR and IGF-1R known ligands. In contrast to the widespread patterns of expression to IR and IGF-1R, IRR demonstrates a very restricted cellular distribution in a subset of tissues of neuronal origin and its biological functions are still unknown.
Subcellular location: Extracellular
Synonyms: INSRR, Insulin receptor related receptor precursor, IR related receptor, IRR, Sirr, Insulin receptor-related protein, IR-related receptor, Insulin receptor-related protein beta chain, INSRR_HUMAN.
Application DetailsProduct Details anti-INSRR Antibody Target Details INSRR Handling Images back to top
|Application Notes||IF(IHC-P) 1:50-200|
|Restrictions||For Research Use only|
HandlingProduct Details anti-INSRR Antibody Target Details INSRR Application Details Images back to top
|Buffer||Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.|
|Precaution of Use||This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.|
|Storage Comment||Store at 4°C|
|Expiry Date||12 months|