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anti-Mouse (Murine) INSRR antibody for Immunohistochemistry (Paraffin-embedded Sections)

Recommended INSRR Antibody (supplied by: Log in to see )

Antigen
Insulin Receptor-Related Receptor (INSRR) Antibodies
  • INSRR
  • Insrr
  • Irr
  • IRR
  • MGC68585
  • Sirr
Epitope
N-Term
27
15
9
6
4
2
2
1
1
1
1
Reactivity
Human, Mouse (Murine)
63
26
19
Host
Rabbit
60
8
Clonality
Polyclonal
Conjugate
This INSRR antibody is un-conjugated
5
5
5
4
4
4
1
1
1
1
1
1
1
1
1
Application
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
52
42
13
11
10
1
1
Supplier
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Catalog No. ABIN359888
$ 390.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.00089245656 ABIN392004 IHC (p) WB Rabbit Ig AA 16-47, N-Term Log in to see Polyclonal 1
0.00089245656 ABIN902834 IHC (p) WB Biotin Rabbit IgG Log in to see Polyclonal
0.00089245656 ABIN902843 IHC (p) WB HRP Rabbit IgG Log in to see Polyclonal
0.00089245656 ABIN872418 IF (p) IHC (p) WB Rabbit IgG Log in to see Polyclonal

Top referenced anti-INSRR antibody for Immunohistochemistry (Paraffin-embedded Sections)

Similar anti-INSRR Antibodies

Application / Reactivity Mouse (Murine) Human
ELISA 5 Antibodies 40 Antibodies
Enzyme Immunoassay (EIA) 1 Antibodies 2 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 11 Antibodies 11 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 5 Antibodies 11 Antibodies
Western Blotting (WB) 14 Antibodies 49 Antibodies
ELISA (Capture) 1 Antibodies
Immunohistochemistry (IHC) 13 Antibodies

General

Antigen Insulin Receptor-Related Receptor (INSRR) Antibodies
Epitope N-Term
(27), (15), (9), (6), (4), (2), (2), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine)
(63), (26), (19)
Host Rabbit
(60), (8)
Clonality
Polyclonal
Conjugate This INSRR antibody is un-conjugated
(5), (5), (5), (4), (4), (4), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(52), (42), (13), (11), (10), (1), (1)
Pubmed 4 references available
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Product Details anti-INSRR Antibody

Target Details INSRR Application Details Handling References for anti-INSRR Antibody (ABIN359888) Images
Specificity This antibody reacts to INSRR (Insulin Receptor R).
Purification Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
Immunogen This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human INSRR.
Isotype Ig

Target Details INSRR

Product Details anti-INSRR Antibody Application Details Handling References for anti-INSRR Antibody (ABIN359888) Images back to top
Antigen
Alternative Name INSRR / IRR (INSRR Antibody Abstract)
Background Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The tyrosine kinase (TK) group is mainly involved in the regulation of cell-cell interactions such as differentiation, adhesion, motility and death. There are currently about 90 TK genes sequenced, 58 are of receptor protein TK (e.g. EGFR, EPH, FGFR, PDGFR, TRK, and VEGFR families), and 32 of cytosolic TK (e.g. ABL, FAK, JAK, and SRC families).Synonyms: INSR-related receptor, Insulin receptor-related protein
Gene ID 3645, 9606
UniProt P14616
Pathways RTK Signaling

Application Details

Product Details anti-INSRR Antibody Target Details INSRR Handling References for anti-INSRR Antibody (ABIN359888) Images back to top
Application Notes ELISA: 1/1,000. Western blotting: 1/100 - 1/500. Immunohistochemistry: 1/10 - 1/50.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-INSRR Antibody Target Details INSRR Application Details References for anti-INSRR Antibody (ABIN359888) Images back to top
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

References for anti-INSRR Antibody (ABIN359888)

Product Details anti-INSRR Antibody Target Details INSRR Application Details Handling Images back to top
Background publications

Whitmore, Maurer, Day, Jelmberg, Dasovich, Sundborg, Burkhead, Heipel, Madden, Kramer, Kuijper, Xu, Jaspers, Holly, Lok: "The assignment of the human insulin receptor-related receptor gene (INSRR) to chromosome 1q21-->q23 by the use of radiation hybrid mapping." in: Cytogenetics and cell genetics, Vol. 87, Issue 1-2, pp. 93-4, 2000

Shier, Watt: "Primary structure of a putative receptor for a ligand of the insulin family." in: The Journal of biological chemistry, Vol. 264, Issue 25, pp. 14605-8, 1989

Wehrenberg, Bloch, Chong-Li, Brazeau, Ling, Guillemin: "Pituitary response to growth hormone-releasing factor in rats with functional or anatomical lesions of the central nervous system that inhibit endogenous growth hormone secretion." in: Regulatory peptides, Vol. 8, Issue 1, pp. 1-8, 1984

Kracht, Hachmeister: "The demonstration of hormones in tissues by means of antibodies. Methodological problems in the use of immunohistological techniques for the localization of hormones." in: Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et métabolisme, Vol. 3, pp. Suppl 3:2-5, 1972

Images

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Supplier Images
 image for anti-INSRR antibody (Insulin Receptor-Related Receptor) (N-Term) (ABIN359888) anti-Insulin Receptor-Related Receptor (INSRR) (N-Term) antibody
 image for anti-INSRR antibody (Insulin Receptor-Related Receptor) (N-Term) (ABIN359888) anti-Insulin Receptor-Related Receptor (INSRR) (N-Term) antibody (Image 2)