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anti-Human MST1R antibody for Enzyme Immunoassay

Recommended MST1R Antibody (supplied by: Log in to see )

Antigen
Macrophage Stimulating 1 Receptor (C-Met-Related tyrosine Kinase) (MST1R) Antibodies
  • CD136
  • Cdw136
  • CDw136
  • Fv-2
  • Fv2
  • Ptk8
  • PTK8
  • RON
  • Ron
  • Stk
  • STK
Epitope
N-Term, C-Term, AA 22-51
32
28
26
15
13
13
13
11
8
6
6
5
3
3
3
2
1
1
1
1
1
Reactivity
Human
168
62
33
1
1
1
1
Host
Rabbit
163
20
4
Clonality
Polyclonal
Conjugate
This MST1R antibody is un-conjugated
12
12
10
10
8
8
2
2
2
2
2
2
2
2
2
1
1
Application
Enzyme Immunoassay (EIA), Western Blotting (WB)
98
91
30
25
24
2
2
1
1
1
1
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Catalog No. ABIN359935
$ 390.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.0008833851 ABIN453814 EIA WB Rabbit AA 163-514 Log in to see Polyclonal 5

Top referenced anti-MST1R antibody for Enzyme Immunoassay

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Application / Reactivity Human
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Enzyme Immunoassay (EIA) 2 Antibodies
Flow Cytometry (FACS) 3 Antibodies
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Immunohistochemistry (IHC) 12 Antibodies
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General

Antigen Macrophage Stimulating 1 Receptor (C-Met-Related tyrosine Kinase) (MST1R) Antibodies
Epitope N-Term, C-Term, AA 22-51
(32), (28), (26), (15), (13), (13), (13), (11), (8), (6), (6), (5), (3), (3), (3), (2), (1), (1), (1), (1), (1)
Reactivity Human
(168), (62), (33), (1), (1), (1), (1)
Host Rabbit
(163), (20), (4)
Clonality
Polyclonal
Conjugate This MST1R antibody is un-conjugated
(12), (12), (10), (10), (8), (8), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1)
Application Enzyme Immunoassay (EIA), Western Blotting (WB)
(98), (91), (30), (25), (24), (2), (2), (1), (1), (1), (1)
Pubmed 6 references available
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Product Details anti-MST1R Antibody

Target Details MST1R Application Details Handling References for anti-MST1R Antibody (ABIN359935) Images
Specificity This antibody recognizes CD136/RON.
Purification Protein G Chromatography, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
Immunogen This antibody is generated from rabbits immunized with two KLH conjugated synthetic peptides between 22~51 amino acids from the N-terminal and C-terminal regions of Human RON. Genename: MST1R
Isotype Ig

Target Details MST1R

Product Details anti-MST1R Antibody Application Details Handling References for anti-MST1R Antibody (ABIN359935) Images back to top
Antigen
Alternative Name CD136 / MST1R (MST1R Antibody Abstract)
Background Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The tyrosine kinase (TK) group is mainly involved in the regulation of cell-cell interactions such as differentiation, adhesion, motility and death. There are currently about 90 TK genes sequenced, 58 are of receptor protein TK (e.g. EGFR, EPH, FGFR, PDGFR, TRK, and VEGFR families), and 32 of cytosolic TK (e.g. ABL, FAK, JAK, and SRC families).Synonyms: MSP receptor, Macrophage-Stimulating 1 Receptor, Macrophage-stimulating protein receptor, Macrophage-stimulating protein receptor alpha chain, Macrophage-stimulating protein receptor beta chain, PTK8, RON, p185-Ron
Gene ID 4486, 9606
UniProt Q04912
Research Area Receptors
Pathways RTK Signaling

Application Details

Product Details anti-MST1R Antibody Target Details MST1R Handling References for anti-MST1R Antibody (ABIN359935) Images back to top
Application Notes ELISA: 1/1,000. Western blotting: 1/100 - 1/500.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-MST1R Antibody Target Details MST1R Application Details References for anti-MST1R Antibody (ABIN359935) Images back to top
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS, 0.09 % (W/V) Sodium Azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

References for anti-MST1R Antibody (ABIN359935)

Product Details anti-MST1R Antibody Target Details MST1R Application Details Handling Images back to top
Background publications

Kobayashi, Furukawa, Kikuchi, Ito, Miyata, Muto, Tanaka, Kusano: "Transactivation of RON receptor tyrosine kinase by interaction with PDGF receptor beta during steady-state growth of human mesangial cells." in: Kidney international, Vol. 75, Issue 11, pp. 1173-83, 2009

Maggiora, Lorenzato, Fracchioli, Costa, Castagnaro, Arisio, Katsaros, Massobrio, Comoglio, Flavia Di Renzo: "The RON and MET oncogenes are co-expressed in human ovarian carcinomas and cooperate in activating invasiveness." in: Experimental cell research, Vol. 288, Issue 2, pp. 382-9, 2003

Santoro, Gaudino, Marchisio: "The MSP receptor regulates alpha6beta4 and alpha3beta1 integrins via 14-3-3 proteins in keratinocyte migration." in: Developmental cell, Vol. 5, Issue 2, pp. 257-71, 2003

Penengo, Rubin, Yarden, Gaudino: "c-Cbl is a critical modulator of the Ron tyrosine kinase receptor." in: Oncogene, Vol. 22, Issue 24, pp. 3669-79, 2003

Zhou, He, Chen, Wang, Wang: "Altered expression of the RON receptor tyrosine kinase in primary human colorectal adenocarcinomas: generation of different splicing RON variants and their oncogenic potential." in: Oncogene, Vol. 22, Issue 2, pp. 186-97, 2003

Danilkovitch-Miagkova, Duh, Kuzmin, Angeloni, Liu, Miller, Lerman: "Hyaluronidase 2 negatively regulates RON receptor tyrosine kinase and mediates transformation of epithelial cells by jaagsiekte sheep retrovirus." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 100, Issue 8, pp. 4580-5, 2003

Images

Product Details anti-MST1R Antibody Target Details MST1R Application Details Handling References for anti-MST1R Antibody (ABIN359935) back to top
Supplier Images
 image for anti-MST1R antibody (Macrophage Stimulating 1 Receptor (C-Met-Related tyrosine Kinase)) (N-Term) (ABIN359935) anti-Macrophage Stimulating 1 Receptor (C-Met-Related tyrosine Kinase) (MST1R) (AA 22-51), (C-Term), (N-Term) antibody