anti-Mouse (Murine) Neuregulin 1 antibody for Immunohistochemistry (Paraffin-embedded Sections)

Recommended Neuregulin 1 Antibody (supplied by: Log in to see )

Antigen
Neuregulin 1 (NRG1) Antibodies
  • NRG1
  • wu:fm70e01
  • DKFZp459A1838
  • HPRG
  • HRGP
  • THPH11
  • HRG1
  • ARIA
  • GGF
  • GGF2
  • HGL
  • HRG
  • HRGA
  • MST131
  • NDF
  • SMDF
  • 6030402G23Rik
  • D230005F13Rik
  • GGFII
  • HRGalpha
  • Hgl
  • pro-neuregulin-1
  • NRG-1
  • heregulin
  • nrg1-A
  • neuregulin 1
  • histidine-rich glycoprotein
  • NRG1
  • nrg1
  • Nrg1
  • HRG
  • Hrg
Epitope
Isoform 10, N-Term
23
19
16
14
11
10
8
7
7
7
6
5
5
5
5
4
4
4
3
3
3
3
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
239
80
76
3
3
2
1
1
1
1
1
Host
Rabbit
203
69
Clonality
Polyclonal
Conjugate
This Neuregulin 1 antibody is un-conjugated
21
13
7
4
4
4
3
3
3
3
3
3
3
3
3
3
3
2
2
2
1
1
1
1
1
1
1
1
1
Application
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
225
128
69
43
19
16
15
11
8
5
5
5
5
3
3
1
Supplier
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Catalog No. ABIN5611483
$ 542.85
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
13.588177 ABIN734828 IF (p) IHC (p) WB Rabbit IgG Log in to see Polyclonal
13.588177 ABIN4234640 IHC (p) Mouse IgG2a Log in to see 7D5
1 ABIN3181069 ELISA IHC (p) WB Rabbit IgG Internal Region Log in to see Polyclonal
1 ABIN2878733 IHC (p) ELISA WB Rabbit IgG AA 1-50 Log in to see Polyclonal
1 ABIN1737529 IHC (p) ELISA WB Rabbit IgG Isoform 10 Log in to see Polyclonal
1 ABIN265466 EIA IF IHC (p) WB Rabbit Log in to see Polyclonal
1 ABIN385444 IHC (p) IP WB Mouse IgG2a Extracellular Log in to see 7D5
1 ABIN734837 IHC (p) WB HRP Rabbit IgG Log in to see Polyclonal
1 ABIN2891448 IF IHC (p) WB Rabbit pTyr4 Log in to see Polyclonal
1 ABIN385448 IHC (p) IP WB Biotin Mouse IgG2a Extracellular Log in to see 7D5
1 ABIN734830 IHC (p) WB Biotin Rabbit IgG Log in to see Polyclonal
1 ABIN385446 IHC (p) IP WB Biotin Mouse IgG2a Extracellular Log in to see 7D5
1 ABIN379113 IHC (p) Mouse IgG2a Extracellular Domain Log in to see 7D5
1 ABIN379114 IHC (p) Mouse IgG2a Extracellular Domain Log in to see 7D5
1 ABIN3031973 ICC IHC (fro) IHC (p) WB Rabbit IgG C-Term Log in to see Polyclonal

General

Antigen Neuregulin 1 (NRG1) Antibodies
Epitope Isoform 10, N-Term
(23), (19), (16), (14), (11), (10), (8), (7), (7), (7), (6), (5), (5), (5), (5), (4), (4), (4), (3), (3), (3), (3), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine), Rat (Rattus)
(239), (80), (76), (3), (3), (2), (1), (1), (1), (1), (1)
Host Rabbit
(203), (69)
Clonality
Polyclonal
Conjugate This Neuregulin 1 antibody is un-conjugated
(21), (13), (7), (4), (4), (4), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(225), (128), (69), (43), (19), (16), (15), (11), (8), (5), (5), (5), (5), (3), (3), (1)
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Product Details anti-Neuregulin 1 Antibody

Target Details Neuregulin 1 Application Details Handling Images
Specificity This antibody detects endogenous levels of total NRG1 isoform-10 protein.
Cross-Reactivity (Details) Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.
Purification Immunoaffinity Chromatography
Immunogen Synthetic peptide - KLH conjugated Genename: NRG1
Isotype IgG

Target Details Neuregulin 1

Product Details anti-Neuregulin 1 Antibody Application Details Handling Images back to top
Antigen
Alternative Name Neuregulin 1 (NRG1 Antibody Abstract)
Background Neuregulin 1 (NRG1) was originally identified as a 44-kD glycoprotein that interacts with the NEU/ERBB2 receptor tyrosine kinase to increase its phosphorylation on tyrosine residues. It is known that an extraordinary variety of different isoforms are produced from the NRG1 gene by alternative splicing. These isoforms include heregulins (HRGs), glial growth factors (GGFs) and sensory and motor neuron-derived factor (SMDF). They are tissue-specifically expressed and differ significantly in their structure. The HRG isoforms all contain immunoglobulin (Ig) and epidermal growth factor-like (EGF-like) domains. GGF and GGF2 isoforms contain a kringle-like sequence plus Ig and EGF-like domains, and the SMDF isoform shares only the EGF-like domain with other isoforms. The receptors for all NRG1 isoforms are the ERBB family of tyrosine kinase transmembrane receptors. Through interaction with ERBB receptors, NRG1 isoforms induce the growth and differentialtion of epithelial, neuronal, glial, and other types of cells.Synonyms: Acetylcholine receptor-inducing activity, Breast cancer cell differentiation factor p45, GGF, Glial growth factor, HGL, HRG, HRGA, Heregulin, NDF, NRG1, Neu differentiation factor, Pro-neuregulin-1 membrane-bound isoform, SMDF, Sensory and motor neuron-derived factor
Gene ID 3084
NCBI Accession NP_001153467
UniProt Q02297
Research Area Growth Factors
Pathways RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Muscle Cell Differentiation

Application Details

Product Details anti-Neuregulin 1 Antibody Target Details Neuregulin 1 Handling Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-Neuregulin 1 Antibody Target Details Neuregulin 1 Application Details Images back to top
Concentration 1.0 mg/mL
Buffer PBS (without Mg2+, Ca2+), pH 7.4 containing 150 mM Sodium Chloride, 0.02 % Sodium Azide and 50 % Glycerol
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Images

Product Details anti-Neuregulin 1 Antibody Target Details Neuregulin 1 Application Details Handling back to top
Supplier Images
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Neuregulin 1 (NRG1) (Isoform 10), (N-Term) antibody (ABIN5611483) Human Tonsil: Formalin-Fixed, Paraffin-Embedded (FFPE)
Western Blotting (WB) image for anti-Neuregulin 1 (NRG1) (Isoform 10), (N-Term) antibody (ABIN5611483) Western blot analysis of extracts from SKOV3 cells, using NRG1 isoform-10 Antibody. T...