Browse our anti-NFAT1 (NFAT1) Antibodies

Full name:
anti-Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 2 Antibodies (NFAT1)
On www.antibodies-online.com are 151 Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 2 (NFAT1) Antibodies from 21 different suppliers available. Additionally we are shipping NFAT1 Proteins (7) and NFAT1 Kits (6) and many more products for this protein. A total of 170 NFAT1 products are currently listed.
Synonyms:
AI607462, NF-ATc2, NFAT1, NFAT1-D, NFATC2, NFATP
list all antibodies Gene Name GeneID UniProt
NFAT1 18019 Q60591
NFAT1 4773 Q13469
NFAT1 311658  

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Most Popular Reactivities for anti-NFAT1 (NFAT1) Antibodies

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anti-Mouse (Murine) NFAT1 Antibodies:

anti-Human NFAT1 Antibodies:

anti-Rat (Rattus) NFAT1 Antibodies:

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Top referenced anti-NFAT1 Antibodies

  1. Human Monoclonal NFAT1 Primary Antibody for ChIP, ELISA - ABIN152663 : Bonnet, Rochefort, Sutendra, Archer, Haromy, Webster, Hashimoto, Bonnet, Michelakis: The nuclear factor of activated T cells in pulmonary arterial hypertension can be therapeutically targeted. in Proceedings of the National Academy of Sciences of the United States of America 2007 (PubMed)
    Show all 8 references for 152663

  2. Dog (Canine) Monoclonal NFAT1 Primary Antibody for IF, IP - ABIN968123 : Boise, Petryniak, Mao, June, Wang, Lindsten, Bravo, Kovary, Leiden, Thompson: The NFAT-1 DNA binding complex in activated T cells contains Fra-1 and JunB. in Molecular and cellular biology 1993 (PubMed)
    Show all 5 references for 968123

  3. Cow (Bovine) Polyclonal NFAT1 Primary Antibody for WB - ABIN2779960 : Glud, Sørensen, Andrulis, Wang, Kondo, Jessen, Krenacs, Stelkovics, Wabl, Serfling, Palmetshofer, Pedersen: A tumor-suppressor function for NFATc3 in T-cell lymphomagenesis by murine leukemia virus. in Blood 2005 (PubMed)
    Show all 3 references for 2779960

  4. Human Polyclonal NFAT1 Primary Antibody for EIA - ABIN358367 : Golks, Tran, Goetschy, Guerini: Requirement for O-linked N-acetylglucosaminyltransferase in lymphocytes activation. in The EMBO journal 2007 (PubMed)
    Show all 3 references for 358367

  5. Human Monoclonal NFAT1 Primary Antibody for IF, IP - ABIN967558 : Crabtree: Contingent genetic regulatory events in T lymphocyte activation. in Science (New York, N.Y.) 1989 (PubMed)
    Show all 2 references for 967558

  6. Human Polyclonal NFAT1 Primary Antibody for ELISA, IHC - ABIN4339294 : Celil Aydemir, Lee, Won Kim, Gardner, Prince, Mok Ahn, Lee, Young-In Lee: Nuclear factor of activated T cell mediates proinflammatory gene expression in response to mechanotransduction. in Annals of the New York Academy of Sciences 2007 (PubMed)

More Antibodies against NFAT1 Interaction Partners

Mouse (Murine) Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 2 (NFAT1) interaction partners

  1. These results demonstrate a repressor role for NFAT1 in cell cycle progression and Cyclin E (show CCNE1 Antibodies) expression in B lymphocytes, and suggest a potential function for NFAT1 protein in B cell malignancies.

  2. Overexpression of either ca-Nfatc2 or ca-Nfatc1 (show NFATC1 Antibodies) in mouse islets enhanced insulin (show INS Antibodies) secretion, whereas only ca-Nfatc2 was able to promote b-cell proliferation, suggesting distinct molecular pathways mediating insulin (show INS Antibodies) secretion vs. b-cell proliferation are regulated by NFAT (show NFATC1 Antibodies)

  3. our results suggest the NFAT1 plays a pivotal role as a genetic switch in CD4 (show CD4 Antibodies)(+)/CD8 (show CD8A Antibodies)(+) T cell tolerance by regulating AICD process in the T cell mediated skin inflammation.

  4. It is a non-Hsp gene, which is essential for HSF1 (show HSF1 Antibodies)-mediated maintenance of whole body homeostasis

  5. NFAT (show NFATC1 Antibodies) directs signaling enzymes to gene promoters in islets.

  6. FOXP3 (show FOXP3 Antibodies) can inhibit NFAT (show NFATC1 Antibodies) driven expression of CD40L (show CD40LG Antibodies) and IL-17 (show IL17A Antibodies) in CD4 (show CD4 Antibodies) T cells through its interaction with NFAT1 and inhibition of this interaction by a short synthetic peptide can modulate effector T cell activity

  7. Nfatc2 and Tob1 have non-overlapping function in T cell negative regulation and tumorigenesis.

  8. our findings reveal a new signaling pathway in microglia that couples TLR4 (show TLR4 Antibodies) activation with the translocation of NFAT1 into mitochondria to control the microglial activation during brain infection.

  9. In Nfat1(-/-) CD4 (show CD4 Antibodies)(+) T cells, the expression of anti-inflammatory lymphokines was mediated by NFAT2 (show NFATC1 Antibodies), thus directly enabling protective IL expression.

  10. Nfatc2 activation in osteoblasts inhibits bone formation and causes cancellous bone osteopenia.

Human Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 2 (NFAT1) interaction partners

  1. NFAT1 overexpression is associated with Melanoma Tumor Growth and Metastasis.

  2. These results demonstrate a repressor role for NFAT1 in cell cycle progression and Cyclin E (show CCNE1 Antibodies) expression in B lymphocytes, and suggest a potential function for NFAT1 protein in B cell malignancies.

  3. revealed more than 170 NFAT (show NFATC1 Antibodies)-associated proteins, half of which are involved in transcriptional regulation. Among them are many hitherto unknown interaction partners of NFATc1 (show NFATC1 Antibodies) and NFATc2 in T cells, such as Raptor (show RPTOR Antibodies), CHEK1 (show CHEK1 Antibodies), CREB1 (show CREB1 Antibodies), RUNX1 (show RUNX1 Antibodies), SATB1 (show SATB1 Antibodies), Ikaros (show IKZF1 Antibodies), and Helios (show ZNFN1A2 Antibodies).

  4. NFAT1 silencing could suppress cell migration and invasion through MMP-3 (show MMP3 Antibodies).

  5. FOXP1 (show FOXP1 Antibodies) has protein-protein interaction with NFAT1 on DNA and enhances breast cancer cell migration by repressing NFAT1 transcriptional activity.

  6. we describe a novel mechanism by which GSK-3beta (show GSK3b Antibodies) fine-tunes NFATc2 and STAT3 (show STAT3 Antibodies) transcriptional networks to integrate upstream signaling events that govern pancreatic cancer progression and growth.

  7. Up-regulation of Store-operated Ca2 (show CA2 Antibodies)+ Entry and Nuclear Factor of Activated T Cells Promote the Acinar Phenotype of the Primary Human Salivary Gland Cells.

  8. two NFAT isoforms (NFAT4 and NFAT1) have shifted band-pass windows for the same receptor in the GPCR signaling pathway

  9. Data indicate that RNA interference of NFAT (show NFATC1 Antibodies) isoforms NFATc1 (show NFATC1 Antibodies), NFATc2, NFATc3 (show NFATC3 Antibodies) and NFATc4 (show NFATC4 Antibodies) regulate gene expression differentially in human retinal microvascular endothelial cells (HRMEC).

  10. These data suggest that NFATc2 expression is regulated by intracellular calcium and in vitro stretch, and that the stretch response in human myometrial cells is dependent upon intracellular calcium signalling pathways.

NFAT1 Antigen Profile

Antigen Summary

This gene is a member of the nuclear factor of activated T cells (NFAT) family. The product of this gene is a DNA-binding protein with a REL-homology region (RHR) and an NFAT-homology region (NHR). This protein is present in the cytosol and only translocates to the nucleus upon T cell receptor (TCR) stimulation, where it becomes a member of the nuclear factors of activated T cells transcription complex. This complex plays a central role in inducing gene transcription during the immune response. Alternate transcriptional splice variants encoding different isoforms have been characterized.

Alternative names and synonyms associated with NFAT1

  • nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 (NFATC2) antibody
  • nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 (nfatc2) antibody
  • nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 2 (Nfatc2) antibody
  • nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 (Nfatc2) antibody
  • AI607462 antibody
  • NF-ATc2 antibody
  • NFAT1 antibody
  • NFAT1-D antibody
  • NFATC2 antibody
  • NFATP antibody

Protein level used designations for NFAT1

nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 , nuclear factor of activated T-cells, cytoplasmic 2-like , NF-ATp , NFAT pre-existing subunit , T-cell transcription factor NFAT1 , nuclear factor of activated T-cells, cytoplasmic 2 , NF-ATc2 , NFAT transcription complex, preexisting component , T cell transcription factor NFAT1 , nuclear factor of activated T-cells, preexisting component , preexisting nuclear factor of activated T-cells 2

GENE ID SPECIES
100052657 Equus caballus
469972 Pan troglodytes
100450332 Pongo abelii
100464798 Ailuropoda melanoleuca
100542144 Meleagris gallopavo
100556205 Anolis carolinensis
100599959 Nomascus leucogenys
710601 Macaca mulatta
100414856 Callithrix jacchus
100490186 Xenopus (Silurana) tropicalis
18019 Mus musculus
4773 Homo sapiens
311658 Rattus norvegicus
485930 Canis lupus familiaris
100134969 Sus scrofa
530401 Bos taurus
419346 Gallus gallus
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