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|Application / Reactivity||Rat (Rattus)||Mouse (Murine)||Human|
|Western Blotting (WB)||37 Antibodies||54 Antibodies||105 Antibodies|
|Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))||14 Antibodies||9 Antibodies||9 Antibodies|
|Immunohistochemistry (IHC)||64 Antibodies||42 Antibodies||26 Antibodies|
|Immunohistochemistry (Frozen Sections) (IHC (fro))||1 Antibodies||2 Antibodies||2 Antibodies|
|Immunofluorescence (IF)||2 Antibodies||2 Antibodies||9 Antibodies|
|Immunocytochemistry (ICC)||2 Antibodies|
|Antigen||Neurotrophic tyrosine Kinase, Receptor, Type 3 (NTRK3) Antibodies|
|Epitope||AA 1-429, Extracellular Domain, N-Term Alternatives|
|Reactivity||Human, Mouse (Murine), Rat (Rattus) Alternatives|
|Conjugate||This NTRK3 antibody is un-conjugated Alternatives|
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
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Product Details anti-NTRK3 AntibodyTarget Details NTRK3 Application Details Handling Images
|Specificity||This antibody recognizes Rat TrkC, Mr 145 kDa and an additional band at ~105 kDa.|
Species reactivity (expected):Human and Mouse.
Species reactivity (tested):Rat.
|Purification||Protein G Chromatography.|
|Immunogen||The entire extracellular domain of rat TrkC receptor, corresponding to amino acids 1-429, expressed in COS cells.|
Target Details NTRK3Product Details anti-NTRK3 Antibody Application Details Handling Images back to top
|Alternative Name||TrkC (NTRK3 Antibody Abstract)|
|Background||The Trk family of tyrosine protein kinase receptors is responsible for mediating the trophic effects of the NGF family of neurotrophins. TrkC is mainly expressed in nervous tissue and is a functional receptor for neurotrophin 3 (NT3). Although it is primarily expressed in neural lineages, expression can also be detected in some non neural cells. Four forms of TrkC are produced by alternative splicing. Isoform A is full length TrkC. Isoform B differs from A between amino acids 529 to 612 and is missing amino acids 613 to 839. Isoform C of TrkC is missing amino acids 712 to 725. Isoform D is missing amino acids 402 to 410.Synonyms: GP145-TrkC, NT-3 growth factor receptor, NTRK3, Neurotrophic tyrosine kinase receptor type 3, TrkC tyrosine kinase|
|Pathways||RTK Signaling, Neurotrophin Signaling Pathway|
Application DetailsProduct Details anti-NTRK3 Antibody Target Details NTRK3 Handling Images back to top
Western Blot: 0.5-2 μg/mLImmunohistochemistry on Paraffin Sections: 2.5 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
|Restrictions||For Research Use only|
HandlingProduct Details anti-NTRK3 Antibody Target Details NTRK3 Application Details Images back to top
|Buffer||0.1 M Tris-glycine, pH 7.4 containing 0.15 M Sodium Chloride, 0.05 % Sodium Azide as preservative and 30 % Glycerol as stabilizer.|
|Precaution of Use||This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.|
|Handling Advice||Avoid repeated freezing and thawing.|
|Storage||4 °C/-20 °C|
|Storage Comment||Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.|
ImagesProduct Details anti-NTRK3 Antibody Target Details NTRK3 Application Details Handling back to top