anti-Rat (Rattus) RHEB antibody for Enzyme Immunoassay

Recommended RHEB Antibody (supplied by: Log in to see )

Antigen
Ras Homolog Enriched in Brain (RHEB) Antibodies
  • RHEB
  • rheb2
  • im:7161941
  • zgc:153231
  • RHEB2
  • Ras homolog enriched in brain
  • ras homolog enriched in brain
  • RHEB
  • rheb
  • Rheb
Epitope
Center
15
10
9
8
8
7
7
5
2
2
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
134
80
60
4
3
2
2
2
2
2
1
1
1
1
1
1
1
Host
Rabbit
87
47
Clonality
Polyclonal
Conjugate
This RHEB antibody is un-conjugated
4
3
3
3
3
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
Application
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
110
31
27
15
13
7
4
2
1
Supplier
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Catalog No. ABIN5555170
$ 375.38
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN5555169 EIA WB Rabbit IgG N-Term Log in to see Polyclonal

General

Antigen Ras Homolog Enriched in Brain (RHEB) Antibodies
Epitope Center
(15), (10), (9), (8), (8), (7), (7), (5), (2), (2), (1), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine), Rat (Rattus)
(134), (80), (60), (4), (3), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1)
Host Rabbit
(87), (47)
Clonality
Polyclonal
Conjugate This RHEB antibody is un-conjugated
(4), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(110), (31), (27), (15), (13), (7), (4), (2), (1)
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Product Details anti-RHEB Antibody

Target Details RHEB Application Details Handling Images
Specificity This antibody detects Rheb at center.
Cross-Reactivity (Details) Species reactivity (tested):Human, mouse, rat
Purification Peptide affinity chromatography
Immunogen Rheb antibody was raised against a 15 amino acid peptide from the middle region of human Rheb.
Isotype IgG

Target Details RHEB

Product Details anti-RHEB Antibody Application Details Handling Images back to top
Antigen
Alternative Name RHEB (RHEB Antibody Abstract)
Background Rheb (Ras homolog enriched in brain) is an evolutionarily conserved member of the Ras family of small GTP-binding proteins originally found to be rapidly induced by synaptic activity in the hippocampus following seizure (1). While it is expressed at relatively high levels in the brain, Rheb is widely expressed in other tissues and may be induced by growth factor stimulation. Similar to other family members, Rheb triggers activation of the Raf-MEK-MAPK pathway (2). Biochemical and genetic studies demon-strate that Rheb has an important role in regulating the insulin/Target of rapamycin (TOR) signaling pathway (3-5). TOR is a serine/threonine protein kinase that acts as a sensor for ATP and amino acids, balancing the availability of nutrients with protein translation and cell growth. A dimeric protein complex termed TSC1/TSC2 indirectly inhibits TOR activity by inhibiting Rheb via the GAP activity of TSC2 (3).Synonyms: GTP-binding protein Rheb, RHEB2, Ras homolog enriched in brain
Gene ID 6009
UniProt Q15382
Research Area Cancer, Transcription Factors
Pathways RTK Signaling

Application Details

Product Details anti-RHEB Antibody Target Details RHEB Handling Images back to top
Application Notes ELISA. Western blot: 1 μg/mL. Immunohistochemistry on paraffin sections
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-RHEB Antibody Target Details RHEB Application Details Images back to top
Buffer PBS containing 0.02 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.