anti-Rat (Rattus) TSC1 antibody for Immunofluorescence

Recommended TSC1 Antibody (supplied by: Log in to see )

Antigen
Tuberous Sclerosis 1 (TSC1) Antibodies
  • tsc1
  • wu:fc38b04
  • LAM
  • TSC
  • hamartin
  • mKIAA0243
  • tuberous sclerosis 1
  • tuberous sclerosis 1b
  • TSC1
  • tsc1b
  • tsc1
  • Tsc1
Epitope
Middle Region
50
40
40
40
40
30
20
20
20
20
20
20
20
20
20
20
20
20
20
20
20
20
20
20
20
20
16
12
12
10
8
7
7
7
5
5
4
4
3
3
3
2
2
2
2
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
462
378
171
28
7
6
5
1
1
Host
Rabbit
742
57
19
2
Clonality
Polyclonal
Conjugate
This TSC1 antibody is un-conjugated
67
67
67
64
64
64
5
5
5
5
5
3
3
3
3
3
3
2
2
Application
Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
532
518
165
66
39
33
27
21
16
8
4
2
1
Supplier
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Catalog No. ABIN303311
$ 500.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN5555392 EIA IF WB Rabbit IgG Middle Region, both Isoforms Log in to see Polyclonal
1 ABIN2650961 IF IHC WB Rabbit IgG Log in to see Polyclonal
1 ABIN121908 IF WB Rabbit Log in to see Polyclonal 2
1 ABIN320501 IF WB Rabbit IgG Log in to see Polyclonal
1 ABIN4363048 ELISA ICC IF WB Rabbit all Isoforms Log in to see Polyclonal
1 ABIN4363049 ELISA ICC IF WB Rabbit all Isoforms Log in to see Polyclonal
1 ABIN2959980 ICC IF ELISA WB Rabbit IgG Middle Region, both Isoforms Log in to see Polyclonal
1 ABIN2983945 ICC IF IHC WB Rabbit IgG Log in to see Polyclonal

Top referenced anti-TSC1 antibody for Immunofluorescence

Similar anti-TSC1 Antibodies

Application / Reactivity Rat (Rattus) Mouse (Murine)
Dot Blot (DB) 76 Antibodies 247 Antibodies
ELISA 76 Antibodies 217 Antibodies
Enzyme Immunoassay (EIA) 1 Antibodies 2 Antibodies
Flow Cytometry (FACS) 2 Antibodies 3 Antibodies
Immunocytochemistry (ICC) 9 Antibodies 9 Antibodies
Immunofluorescence (IF) 9 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 39 Antibodies
Immunohistochemistry (IHC) 6 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 1 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 19 Antibodies
Immunoprecipitation (IP) 1 Antibodies
Western Blotting (WB) 49 Antibodies

General

Antigen Tuberous Sclerosis 1 (TSC1) Antibodies
Epitope Middle Region
(50), (40), (40), (40), (40), (30), (20), (20), (20), (20), (20), (20), (20), (20), (20), (20), (20), (20), (20), (20), (20), (20), (20), (20), (20), (20), (16), (12), (12), (10), (8), (7), (7), (7), (5), (5), (4), (4), (3), (3), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine), Rat (Rattus)
(462), (378), (171), (28), (7), (6), (5), (1), (1)
Host Rabbit
(742), (57), (19), (2)
Clonality
Polyclonal
Conjugate This TSC1 antibody is un-conjugated
(67), (67), (67), (64), (64), (64), (5), (5), (5), (5), (5), (3), (3), (3), (3), (3), (3), (2), (2)
Application Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(532), (518), (165), (66), (39), (33), (27), (21), (16), (8), (4), (2), (1)
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Product Details anti-TSC1 Antibody

Target Details TSC1 Application Details Handling Images
Specificity This antibody will recognize both isoforms of TSC1.
Cross-Reactivity (Details) Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.
Purification Immunoaffinity Chromatography.
Immunogen TSC1 antibody was raised against Synthetic Peptide (KLH conjugated) corresponding to 15 amino acid peptide from the middle region of Human TSC1.

Target Details TSC1

Product Details anti-TSC1 Antibody Application Details Handling Images back to top
Antigen
Alternative Name TSC1 / Hamartin (TSC1 Antibody Abstract)
Background Hamartin, or TSC1, is a suspected tumor suppressor implicated in the disease tuberous sclerosis 1. It is a negative regulator of cell division controlling the transition from G0/G1 to S phase, and it seems to act through the phosphatidylinositol 3 kinase/Akt pathway. TSC1 interacts with tuberin m(TSC2), which is thought to be a GAP (GTPase Activating Protein) for the Rap1 and Rab5 small G Proteins. The Hamartin/Tuberin complex has been shown to inhibit mTor. Hamartin has also been shown to interact with ERM (Ezrin-Radixin-Moesin) proteins and with F-actin, suggesting a role for TSC proteins in modulation of cell adhesion and morphology.Synonyms: KIAA0243, TSC, Tuberous sclerosis 1 protein
Gene ID 7248
NCBI Accession NP_000359
UniProt Q92574
Pathways RTK Signaling, AMPK Signaling, Regulation of Cell Size, Tube Formation

Application Details

Product Details anti-TSC1 Antibody Target Details TSC1 Handling Images back to top
Application Notes Immunocytochemistry. Western Blot (1 μg/mL). Immunohistochemistry on Paraffin Sections (2.5 μg/mL).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-TSC1 Antibody Target Details TSC1 Application Details Images back to top
Concentration 1.0 mg/mL
Buffer PBS containing 0.02 % Sodium Azide as preservative.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C to -70 °C for longer. Dilute only prior to immediate use.

Images

Product Details anti-TSC1 Antibody Target Details TSC1 Application Details Handling back to top
Supplier Images
 image for anti-TSC1 antibody (Tuberous Sclerosis 1) (Middle Region) (ABIN303311) anti-Tuberous Sclerosis 1 (TSC1) (Middle Region) antibody
 image for anti-TSC1 antibody (Tuberous Sclerosis 1) (Middle Region) (ABIN303311) anti-Tuberous Sclerosis 1 (TSC1) (Middle Region) antibody (Image 2)