anti-Rat (Rattus) TSC1 antibody for Immunohistochemistry (Paraffin-embedded Sections)

Recommended TSC1 Antibody (supplied by: Log in to see )

Antigen
Tuberous Sclerosis 1 (TSC1) Antibodies
  • tsc1
  • wu:fc38b04
  • LAM
  • TSC
  • hamartin
  • mKIAA0243
  • tuberous sclerosis 1
  • tuberous sclerosis 1b
  • TSC1
  • tsc1b
  • tsc1
  • Tsc1
Epitope
AA 1150-1164, C-Term
49
43
40
40
40
40
20
20
20
20
20
20
20
20
20
20
20
20
20
20
20
20
20
20
20
16
12
12
10
9
7
7
7
7
5
5
4
4
3
3
3
3
2
2
1
1
1
1
1
1
1
1
1
Reactivity
Human, Rat (Rattus)
463
380
172
28
7
6
5
1
1
Host
Rabbit
743
57
19
2
Clonality
Polyclonal
Conjugate
This TSC1 antibody is un-conjugated
67
67
67
64
64
64
5
5
5
5
5
3
3
3
3
3
3
2
2
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
532
519
166
66
39
33
29
21
17
8
4
2
2
1
Options
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Catalog No. ABIN3044051
$ 200.00
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN2476985 IHC (fro) IHC (p) WB Rabbit IgG Center Log in to see Polyclonal 2
1 ABIN574381 IHC (p) ELISA WB Goat AA 1150-1163 Log in to see Polyclonal
1 ABIN214539 ICC IHC (p) WB Rabbit Middle Region Log in to see Polyclonal
1 ABIN303311 IF IHC (p) WB Rabbit Middle Region Log in to see Polyclonal
1 ABIN711971 IF (p) IHC (p) WB Rabbit IgG pSer505 Log in to see Polyclonal
1 ABIN1740408 IHC (p) ELISA WB Goat C-Term Log in to see Polyclonal
1 ABIN2621707 IHC (p) WB Rabbit IgG AA 1150-1164 Log in to see Polyclonal
1 ABIN1740410 ICC IHC (p) WB Rabbit IgG Log in to see Polyclonal
1 ABIN704855 IHC (p) HRP Rabbit IgG Log in to see Polyclonal
1 ABIN711980 IHC (p) WB HRP Rabbit IgG pSer505 Log in to see Polyclonal
1 ABIN1711351 IHC (p) WB HRP Rabbit IgG Log in to see Polyclonal
1 ABIN704848 IHC (p) Biotin Rabbit IgG Log in to see Polyclonal
1 ABIN711973 IHC (p) WB Biotin Rabbit IgG pSer505 Log in to see Polyclonal
1 ABIN1700334 IHC (p) WB Biotin Rabbit IgG Log in to see Polyclonal
1 ABIN704846 IF (p) IHC (p) Rabbit IgG Log in to see Polyclonal
1 ABIN1713836 IF (p) IHC (p) WB Rabbit IgG Log in to see Polyclonal
1 ABIN599712 IHC (p) WB Mouse IgG1 Log in to see
1 ABIN3029309 IHC (p) WB Rabbit IgG C-Term Log in to see Polyclonal

General

Antigen Tuberous Sclerosis 1 (TSC1) Antibodies
Epitope AA 1150-1164, C-Term
(49), (43), (40), (40), (40), (40), (20), (20), (20), (20), (20), (20), (20), (20), (20), (20), (20), (20), (20), (20), (20), (20), (20), (20), (20), (16), (12), (12), (10), (9), (7), (7), (7), (7), (5), (5), (4), (4), (3), (3), (3), (3), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human, Rat (Rattus)
(463), (380), (172), (28), (7), (6), (5), (1), (1)
Host Rabbit
(743), (57), (19), (2)
Clonality
Polyclonal
Conjugate This TSC1 antibody is un-conjugated
(67), (67), (67), (64), (64), (64), (5), (5), (5), (5), (5), (3), (3), (3), (3), (3), (3), (2), (2)
Application Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(532), (519), (166), (66), (39), (33), (29), (21), (17), (8), (4), (2), (2), (1)
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Product Details anti-TSC1 Antibody

Target Details TSC1 Application Details Handling Images
Purpose Rabbit IgG polyclonal antibody for Hamartin(TSC1) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
Sequence QLHIMDYNET HHEHS
Cross-Reactivity (Details) Predicted Cross Reactivity: mouse
No cross reactivity with other proteins.
Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities.
Characteristics Rabbit IgG polyclonal antibody for Hamartin(TSC1) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
Gene Name: tuberous sclerosis 1
Protein Name: Hamartin
Purification Immunogen affinity purified.
Immunogen A synthetic peptide corresponding to a sequence at the C-terminus of human Hamartin(1150-1164aa QLHIMDYNETHHEHS), identical to the related rat sequence, and different from the related mouse sequence by one amino acid.
Isotype IgG

Target Details TSC1

Product Details anti-TSC1 Antibody Application Details Handling Images back to top
Antigen
Alternative Name TSC1 (TSC1 Antibody Abstract)
Background TSC1(Tuberous Sclerosis 1), also called HAMARTIN or TSC, is a human protein and gene. As part of a comprehensive strategy to identify the gene mutant in tuberous sclerosis-1, van Slegtenhorst et al.(1997) developed an overlapping contig of clones from the 1.4-Mb TSC1 region on chromosome 9. Benvenuto et al.(2000) showed that overexpression of the TSC1 gene in rat fibroblasts inhibits growth and causes changes in cell morphology. Van Slegtenhorst et al.(1998) showed that hamartin and tuberin associate physically in vivo, however, and that the interaction is mediated by predicted coiled-coil domains.

Synonyms: Hamartin antibody|kiaa0243 antibody|LAM antibody|TSC antibody|TSC1 antibody|Tsc1 gene antibody|TSC1_HUMAN antibody|Tuberous sclerosis 1 antibody|Tuberous sclerosis 1 protein antibody
UniProt Q92574
Pathways RTK Signaling, AMPK Signaling, Regulation of Cell Size, Tube Formation

Application Details

Product Details anti-TSC1 Antibody Target Details TSC1 Handling Images back to top
Application Notes WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse, The detection limit for TSC1 is approximately 5 ng/lane under reducing conditions.
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Predicted Species: Mouse, Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.
Comment

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Restrictions For Research Use only

Handling

Product Details anti-TSC1 Antibody Target Details TSC1 Application Details Images back to top
Format Lyophilized
Reconstitution Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
Concentration 500 μg/mL
Buffer Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
Preservative Thimerosal (Merthiolate), Sodium azide
Precaution of Use This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
Expiry Date 12 months

Images

Product Details anti-TSC1 Antibody Target Details TSC1 Application Details Handling back to top
Supplier Images
Immunohistochemistry (IHC) image for anti-Tuberous Sclerosis 1 (TSC1) (AA 1150-1164), (C-Term) antibody (ABIN3044051) Anti-Hamartin antibody, IHC(P) IHC(P): Rat Brain Tissue
Immunohistochemistry (IHC) image for anti-Tuberous Sclerosis 1 (TSC1) (AA 1150-1164), (C-Term) antibody (ABIN3044051) Anti-Hamartin antibody, IHC(P) IHC(P): Human Mammary Cancer Tissue
Western Blotting (WB) image for anti-Tuberous Sclerosis 1 (TSC1) (AA 1150-1164), (C-Term) antibody (ABIN3044051) anti-Tuberous Sclerosis 1 (TSC1) (AA 1150-1164), (C-Term) antibody (Image 3)