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|Application / Reactivity||Mouse (Murine)|
|Enzyme Immunoassay (EIA)||9 Antibodies|
|Flow Cytometry (FACS)||2 Antibodies|
|Functional Studies (Func)||2 Antibodies|
|Immunocytochemistry (ICC)||3 Antibodies|
|Immunofluorescence (IF)||4 Antibodies|
|Immunofluorescence (Paraffin-embedded Sections) (IF (p))||22 Antibodies|
|Immunohistochemistry (IHC)||21 Antibodies|
|Immunohistochemistry (Frozen Sections) (IHC (fro))||3 Antibodies|
|Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))||22 Antibodies|
|Immunoprecipitation (IP)||1 Antibodies|
|Intracellular Flow Cytometry (ICFC)||2 Antibodies|
|Neutralization (Neut)||1 Antibodies|
|Western Blotting (WB)||65 Antibodies|
|Antigen||Vascular Endothelial Growth Factor A (VEGFA) Antibodies|
|Reactivity||Mouse (Murine) Alternatives|
|Conjugate||This VEGF antibody is un-conjugated Alternatives|
Flow Cytometry (FACS)
|9 references available|
|Supplier||Log in to see|
Product Details anti-VEGF AntibodyTarget Details VEGF Application Details Handling References for anti-VEGF Antibody (ABIN2666037) Images
|Purification||The LEAF™ (Low Endotoxin, Azide-Free) antibody was purified by affinity chromatography.|
|Sterility||0.2 μm filtered|
Endotoxin level is <0.1 EU/μg of the protein (<0.01 ng/μg of the protein) as determined by the LAL test.
|Isotype||IgG kappa, IgG2a kappa|
Target Details VEGFProduct Details anti-VEGF Antibody Application Details Handling References for anti-VEGF Antibody (ABIN2666037) Images back to top
|Alternative Name||VEGF-A (VEGFA Antibody Abstract)|
|Background||VEGF-A, also known as VEGF (vascular endothelial growth factor), is the founding member of the family including VEGF (VEGF-A), VEGF-B, VEGF-C, VEGF-D, VEGF-E, and PIGF. Vascular endothelial growth factors (VEGFs) are a family of secreted polypeptides with a highly conserved receptor-binding cystine-knot structure similar to that of the platelet-derived growth factors.VEGF-A has important roles in mammalian vascular development and in diseases involving abnormal growth of blood vessels such as tumor-related angiogenesis.VEGF-A is produced by diverse cell types, including aortic vascular smooth muscle cells, keratinocytes, macrophages and many tumor cells. Oxygen tension is a key physiological regulator of VEGF-A gene expression.|
|Research Area||Cytokines, Growth Factors, Receptors, Immunology, Inflammation, Signaling|
Application DetailsProduct Details anti-VEGF Antibody Target Details VEGF Handling References for anti-VEGF Antibody (ABIN2666037) Images back to top
|Application Notes||Optimal working dilution should be determined by the investigator.|
|Restrictions||For Research Use only|
HandlingProduct Details anti-VEGF Antibody Target Details VEGF Application Details References for anti-VEGF Antibody (ABIN2666037) Images back to top
|Handling Advice||This LEAF™ solution contains no preservative, handle under aseptic conditions.|
|Storage Comment||The VEGF-A antibody solution should be stored undiluted between 2°C and 8°C. This LEAF™ solution contains no preservative, handle under aseptic conditions.|
References for anti-VEGF Antibody (ABIN2666037)Product Details anti-VEGF Antibody Target Details VEGF Application Details Handling Images back to top
Kather, Friedrich, Woik et al.: "Angiopoietin-1 is regulated by miR-204 and contributes to corneal neovascularization in KLEIP-deficient mice." in: Investigative ophthalmology & visual science, Vol. 55, Issue 7, pp. 4295-303, 2014 (PubMed).
Jayaraman, Parikh, Lopez-Rivera et al.: "Tumor-expressed inducible nitric oxide synthase controls induction of functional myeloid-derived suppressor cells through modulation of vascular endothelial growth factor release." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 188, Issue 11, pp. 5365-76, 2012 (PubMed).
Lu, Kujawski, Pan et al.: "Tumor angiogenesis mediated by myeloid cells is negatively regulated by CEACAM1." in: Cancer research, Vol. 72, Issue 9, pp. 2239-50, 2012 (PubMed).
Kumar, Scandella, Danuser et al.: "Global lymphoid tissue remodeling during a viral infection is orchestrated by a B cell-lymphotoxin-dependent pathway." in: Blood, Vol. 115, Issue 23, pp. 4725-33, 2010 (PubMed).
Basu, Contreras, Datta et al.: "Overexpression of vascular endothelial growth factor and the development of post-transplantation cancer." in: Cancer research, Vol. 68, Issue 14, pp. 5689-98, 2008 (PubMed).
Lambrechts, Carmeliet: "VEGF at the neurovascular interface: therapeutic implications for motor neuron disease." in: Biochimica et biophysica acta, Vol. 1762, Issue 11-12, pp. 1109-21, 2006 (PubMed).
Tong, Yao: "Contribution of VEGF and PEDF to choroidal angiogenesis: a need for balanced expressions." in: Clinical biochemistry, Vol. 39, Issue 3, pp. 267-76, 2006 (PubMed).
Ferrara, Gerber, LeCouter: "The biology of VEGF and its receptors." in: Nature medicine, Vol. 9, Issue 6, pp. 669-76, 2003 (PubMed).
Shibuya: "Structure and function of VEGF/VEGF-receptor system involved in angiogenesis." in: Cell structure and function, Vol. 26, Issue 1, pp. 25-35, 2001 (PubMed).
ImagesProduct Details anti-VEGF Antibody Target Details VEGF Application Details Handling References for anti-VEGF Antibody (ABIN2666037) back to top