VEGFR-2 (Vascular endothelial growth factor receptor 2) is a tyrosine-protein kinase and receptor for VEGF or VEGFC. The VEGF-kinase ligand/receptor signaling system plays a key role in vascular development and regulation of vascular permeability. In HIV-1 infection cases, VEGFR2 interaction with extracellular viral Tat protein enhances angiogenesis in Kaposi's sarcoma lesions.
Each vial contains 0.1 mg IgG in 0.1 mL of PBS pH7.4 with 0.09% sodium azide.
Precaution of Use
Warning: This product contains sodium azide, which has been classified as Xn (Harmful), in European Directive 67/548/EEC in the concentration range of 0.1 - 1.0 %. When disposing of this reagent through lead or copper plumbing, flush with copious volumes of water to prevent azide build-up in drains.
Prokosch, Fink, Heiduschka, Melkonyan, Thanos: "VEGF, Ang-2 and SRIF associated abnormal postnatal development of the retinal capillary network in the Royal College of Surgeons rat." in: Experimental eye research, Vol. 92, Issue 2, pp. 128-37, 2011