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|Application / Reactivity||Human||Mouse (Murine)||Rat (Rattus)|
|Western Blotting (WB)||367 Antibodies||177 Antibodies||81 Antibodies|
|Neutralization (Neut)||6 Antibodies|
|Mass Cytometry (CyTOF)||1 Antibodies|
|Intracellular Flow Cytometry (ICFC)||5 Antibodies|
|Immunoprecipitation (IP)||22 Antibodies||10 Antibodies|
|Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))||82 Antibodies||43 Antibodies||32 Antibodies|
|Immunohistochemistry (IHC)||103 Antibodies||201 Antibodies||68 Antibodies|
|Immunohistochemistry (Frozen Sections) (IHC (fro))||22 Antibodies||5 Antibodies||3 Antibodies|
|Antigen||Kinase insert Domain Receptor (A Type III Receptor tyrosine Kinase) (KDR) Antibodies|
|Reactivity||Human, Mouse (Murine), Rat (Rattus) Alternatives|
|Conjugate||This VEGFR2 antibody is un-conjugated Alternatives|
Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
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Product Details anti-VEGFR2 AntibodyTarget Details VEGFR2 Application Details Handling Images
|Specificity||This antibody detects endogenous levels of Flk-1/Flt-4 protein.|
Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.
|Purification||Affinity chromatography using epitope-specific immunogen|
|Purity||> 95 % (by SDS-PAGE)|
Target Details VEGFR2Product Details anti-VEGFR2 Antibody Application Details Handling Images back to top
|Alternative Name||CD309 / VEGFR-2 / Flk-1 (KDR Antibody Abstract)|
|Background||Three cell membrane receptor tyrosine kinases, Flt (also designated VEGF-R1), Flk-1 (also designated VEGF-R2) and Flt-4, putatively involved in the growth of endothelial cells, are characterized by the presence of seven immunoglobulinlike sequences in their extracellular domain. These receptors exhibit high degrees of sequence relatedness to each other as well as lesser degrees of relatedness to the class III receptors including CSF-1/Fms, PDGR, SLFR/Kit and Flt-3/Flk-2. Two members of this receptor class, Flt-1 and Flk-1, have been shown to represent high affinity receptors for vascular endothelial growth factors (VEGFs). On the basis of structural similarity to Flt and Flk-1, it has been speculated that Flt-4 might represent a third receptor for either VEGF or a VEGF-related ligand.Synonyms: FLK1, KDR, Kinase NYK, Kinase insert domain receptor, Protein-tyrosine kinase receptor Flk-1, VEGF Receptor 2, VEGFR2, Vascular endothelial growth factor receptor 2|
|Molecular Weight||approx. 150, 210 kDa|
|Research Area||Cytokines, Receptors|
Application DetailsProduct Details anti-VEGFR2 Antibody Target Details VEGFR2 Handling Images back to top
Immunohistochemistry on paraffin sections: 1: 50 - 1: 200. Immunoflourescence: 1: 50 - 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
|Restrictions||For Research Use only|
HandlingProduct Details anti-VEGFR2 Antibody Target Details VEGFR2 Application Details Images back to top
|Buffer||Phosphate buffered saline (PBS) with 0.05 % sodium azide, approx. pH 7.2|
|Precaution of Use||This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.|
|Handling Advice||Avoid repeated freezing and thawing.|
|Storage||4 °C/-20 °C|
|Storage Comment||Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.|
ImagesProduct Details anti-VEGFR2 Antibody Target Details VEGFR2 Application Details Handling back to top