anti-Mouse (Murine) VEGFR2 antibody for Immunohistochemistry (Paraffin-embedded Sections)

Recommended VEGFR2 Antibody (supplied by: Log in to see )

Antigen
Kinase insert Domain Receptor (A Type III Receptor tyrosine Kinase) (KDR) Antibodies
  • vegfr-2
  • KDR
  • 6130401C07
  • Flk-1
  • Flk1
  • Krd-1
  • Ly73
  • VEGFR-2
  • VEGFR2
  • sVEGFR-2
  • Vegfr-2
  • CD309
  • FLK1
  • VEGFR
  • FLK-1
  • flk-1
  • FLK/KDR
  • flk1
  • flk1b
  • kdrb
  • si:busm1-205d10.1
  • si:ch211-254j6.1
  • si:ch211-278f21.4
  • wu:fc31a09
  • fk52c05
  • flk
  • kdr
  • kdra
  • vegfr2
  • vegfr4
  • vegr2
  • wu:fk52c05
  • vascular endothelial growth factor receptor 2
  • kinase insert domain protein receptor
  • kinase insert domain receptor
  • kinase insert domain receptor (a type III receptor tyrosine kinase)
  • kinase insert domain receptor like
  • vascular endothelial growth factor receptor-2
  • vegfr-2
  • Kdr
  • KDR
  • kdr
  • kdrl
Epitope
AA 150-190
77
58
53
38
25
23
21
18
18
18
16
15
15
15
13
13
13
12
12
11
10
10
9
7
6
6
6
5
5
4
4
4
4
4
4
3
3
3
3
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Pig (Porcine), Rat (Rattus)
611
371
182
24
7
4
4
4
3
3
2
2
1
1
1
1
1
1
1
1
Host
Rabbit
534
141
60
4
2
2
1
Clonality
Polyclonal
Conjugate
This VEGFR2 antibody is un-conjugated
45
32
24
20
18
12
11
9
9
5
5
5
5
4
4
3
3
3
3
3
3
3
3
3
3
3
3
2
2
2
2
1
1
Application
Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
462
239
208
201
118
108
40
34
26
24
19
17
11
9
8
7
6
5
3
2
1
1
1
1
1
1
1
Options
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Catalog No. ABIN2180045
$ 307.45
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
13.400779 ABIN152109 IHC (fro) IHC (p) IHC Rabbit C-Term Log in to see Polyclonal 1
13.400779 ABIN498218 IF IHC (p) Rabbit Log in to see Polyclonal
13.400779 ABIN258820 IHC (p) IHC ELISA WB Mouse IgG1 N-Term Log in to see MM0002-2F66
13.400779 ABIN498809 IHC (p) WB Rabbit pTyr951 Log in to see Polyclonal
13.400779 ABIN498807 IHC (p) Rabbit pTyr1175 Log in to see Polyclonal
13.400779 ABIN498808 IHC (p) Rabbit pTyr1214 Log in to see Polyclonal
13.400779 ABIN2506667 ICC IF IHC (p) ELISA WB Rabbit IgG Log in to see Polyclonal
13.400779 ABIN446800 ICC IF IHC (p) IHC Rabbit Log in to see Polyclonal
13.400779 ABIN498900 IHC (p) Rabbit Log in to see Polyclonal
13.400779 ABIN498899 IHC (p) Rabbit Log in to see Polyclonal
13.400779 ABIN498898 IHC (p) Rabbit Log in to see Polyclonal
1 ABIN181334 IHC (p) WB Rabbit C-Term Log in to see Polyclonal 4
1 ABIN115388 IHC (p) Rabbit C-Term Log in to see Polyclonal 1
1 ABIN115389 IHC (p) Rabbit C-Term Log in to see Polyclonal 2
1 ABIN197236 IF IHC (p) WB Rabbit Tyr1175 Log in to see Polyclonal 2
1 ABIN197238 IF IHC (p) WB Rabbit AA 1212-1216 Log in to see Polyclonal 2
1 ABIN197240 IF IHC (p) WB Rabbit AA 949-953 Log in to see Polyclonal 2
1 ABIN196766 IF IHC (p) Rabbit pTyr1175 Log in to see Polyclonal 2
1 ABIN196770 IF IHC (p) WB Rabbit pTyr951 Log in to see Polyclonal 2
1 ABIN152058 IHC (p) IP IHC WB Rabbit C-Term, AA 1158-1365 Log in to see Polyclonal 8

Top referenced anti-VEGFR2 antibody for Immunohistochemistry (Paraffin-embedded Sections)

Similar anti-VEGFR2 Antibodies

Application / Reactivity Human Mouse (Murine) Rat (Rattus) Pig (Porcine)
Immunofluorescence (fixed cells) (IF/ICC) 8 Antibodies 4 Antibodies 3 Antibodies 2 Antibodies
Cytometry by Time of Flight (CyTOF) 3 Antibodies 1 Antibodies
Western Blotting (WB) 385 Antibodies 231 Antibodies 106 Antibodies 11 Antibodies
Neutralization (Neut) 1 Antibodies 8 Antibodies
Mass Cytometry (CyTOF) 1 Antibodies
Intracellular Flow Cytometry (ICFC) 5 Antibodies
Immunoprecipitation (IP) 25 Antibodies 12 Antibodies 1 Antibodies 1 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 108 Antibodies

General

Antigen Kinase insert Domain Receptor (A Type III Receptor tyrosine Kinase) (KDR) Antibodies
Epitope AA 150-190
(77), (58), (53), (38), (25), (23), (21), (18), (18), (18), (16), (15), (15), (15), (13), (13), (13), (12), (12), (11), (10), (10), (9), (7), (6), (6), (6), (5), (5), (4), (4), (4), (4), (4), (4), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine), Pig (Porcine), Rat (Rattus)
(611), (371), (182), (24), (7), (4), (4), (4), (3), (3), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Host Rabbit
(534), (141), (60), (4), (2), (2), (1)
Clonality
Polyclonal
Conjugate This VEGFR2 antibody is un-conjugated
(45), (32), (24), (20), (18), (12), (11), (9), (9), (5), (5), (5), (5), (4), (4), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (1), (1)
Application Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(462), (239), (208), (201), (118), (108), (40), (34), (26), (24), (19), (17), (11), (9), (8), (7), (6), (5), (3), (2), (1), (1), (1), (1), (1), (1), (1)
Pubmed 4 references available
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Product Details anti-VEGFR2 Antibody

Target Details VEGFR2 Application Details Handling ProductDetails: References for anti-VEGFR2 antibody (ABIN2180045) Images
Purification Purified by Protein A.
Immunogen KLH conjugated synthetic peptide derived from human VEGFR2
Isotype IgG

Target Details VEGFR2

Product Details anti-VEGFR2 Antibody Application Details Handling ProductDetails: References for anti-VEGFR2 antibody (ABIN2180045) Images back to top
Antigen
Alternative Name Vegfr2 (KDR Antibody Abstract)
Background

Tyrosine-protein kinase that acts as a cell-surface receptor for VEGFA, VEGFC and VEGFD. Plays an essential role in the regulation of angiogenesis, vascular development, vascular permeability, and embryonic hematopoiesis. Promotes proliferation, survival, migration and differentiation of endothelial cells. Promotes reorganization of the actin cytoskeleton. Isoforms lacking a transmembrane domain, such as isoform 2 and isoform 3, may function as decoy receptors for VEGFA, VEGFC and/or VEGFD. Isoform 2 plays an important role as negative regulator of VEGFA- and VEGFC-mediated lymphangiogenesis by limiting the amount of free VEGFA and/or VEGFC and preventing their binding to FLT4. Modulates FLT1 and FLT4 signaling by forming heterodimers. Binding of vascular growth factors to isoform 1 leads to the activation of several signaling cascades. Activation of PLCG1 leads to the production of the cellular signaling molecules diacylglycerol and inositol 1,4,5-trisphosphate and the activation of protein kinase C. Mediates activation of MAPK1/ERK2, MAPK3/ERK1 and the MAP kinase signaling pathway, as well as of the AKT1 signaling pathway. Mediates phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase, reorganization of the actin cytoskeleton and activation of PTK2/FAK1. Required for VEGFA-mediated induction of NOS2 and NOS3, leading to the production of the signaling molecule nitric oxide (NO) by endothelial cells. Phosphorylates PLCG1. Promotes phosphorylation of FYN, NCK1, NOS3, PIK3R1, PTK2/FAK1 and SRC.

Subcellular location: Extracellular

Synonyms: FLK1, CD309, VEGFR, VEGFR2, Vascular endothelial growth factor receptor 2, VEGFR-2, Fetal liver kinase 1, FLK-1, Kinase insert domain receptor, KDR, Protein-tyrosine kinase receptor flk-1

Gene ID 3791
UniProt P35968
Pathways RTK Signaling, Glycosaminoglycan Metabolic Process, Signaling Events mediated by VEGFR1 and VEGFR2, Growth Factor Binding, Regulation of long-term Neuronal Synaptic Plasticity

Application Details

Product Details anti-VEGFR2 Antibody Target Details VEGFR2 Handling ProductDetails: References for anti-VEGFR2 antibody (ABIN2180045) Images back to top
Application Notes WB 1:100-1000
FCM 1:20-100
IHC-P 1:100-500
Restrictions For Research Use only

Handling

Product Details anti-VEGFR2 Antibody Target Details VEGFR2 Application Details ProductDetails: References for anti-VEGFR2 antibody (ABIN2180045) Images back to top
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20°C
Expiry Date 12 months

ProductDetails: References for anti-VEGFR2 antibody (ABIN2180045)

Product Details anti-VEGFR2 Antibody Target Details VEGFR2 Application Details Handling Images back to top
Product cited in:

Wang, Chen, Ke, Li: "Ghrelin inhibits atherosclerotic plaque angiogenesis and promotes plaque stability in a rabbit atherosclerotic model." in: Peptides, Vol. 90, pp. 17-26, 2017 Method employed by authors: Western Blotting (WB) (Sample species: Rabbit).

Tan, Yang, Fu, Cui, Guo, Ma, Yin, Leng, Song: "Single-dose local simvastatin injection improves implant fixation via increased angiogenesis and bone formation in an ovariectomized rat model." in: Medical science monitor : international medical journal of experimental and clinical research, Vol. 21, pp. 1428-39, 2015

García Fernández, Sánchez Pérez, Sánchez Maldonado, García-Palencia, Naranjo Freixa, Palomo Yagüe, Flores: "Iberian pig early pregnancy: vascular endothelial growth factor receptor system expression in the maternofetal interface in healthy and arresting conceptuses." in: Theriogenology, Vol. 83, Issue 3, pp. 334-43, 2014

Kuang, Yang, Zhang, Zhang, Wu: "Schlafen 1 inhibits the proliferation and tube formation of endothelial progenitor cells." in: PLoS ONE, Vol. 9, Issue 10, pp. e109711, 2014

Images

Product Details anti-VEGFR2 Antibody Target Details VEGFR2 Application Details Handling ProductDetails: References for anti-VEGFR2 antibody (ABIN2180045) back to top
Supplier Images
Flow Cytometry (FACS) image for anti-VEGFR2 antibody (Kinase insert Domain Receptor (A Type III Receptor tyrosine Kinase)) (AA 150-190) (ABIN2180045) HeLa cells probed with Rabbit Anti-VEGFR2 Polyclonal Antibody (ABIN2180045) at 1:100 ...
Western Blotting (WB) image for anti-VEGFR2 antibody (Kinase insert Domain Receptor (A Type III Receptor tyrosine Kinase)) (AA 150-190) (ABIN2180045) Mouse lung lysates probed with Anti-VEGFR2 Polyclonal Antibody at 1:5000 90min in 37˚C.
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-VEGFR2 antibody (Kinase insert Domain Receptor (A Type III Receptor tyrosine Kinase)) (AA 150-190) (ABIN2180045) Formalin-fixed and paraffin embedded mouse placenta tissue labeled with Anti-VEGFR2 P...