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anti-Rat (Rattus) WASF2 Antibodies:
anti-Human WASF2 Antibodies:
anti-Mouse (Murine) WASF2 Antibodies:
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Human Monoclonal WASF2 Primary Antibody for WB - ABIN393401
Takahashi, Tanaka, Suzuki: Directional control of WAVE2 membrane targeting by EB1 and phosphatidylinositol 3,4,5-triphosphate. in Cellular signalling 2009
Show all 5 references for ABIN393401
Mouse (Murine) Polyclonal WASF2 Primary Antibody for WB - ABIN610903
Frain, Swart, Monaci, Nicosia, Stämpfli, Frank, Cortese: The liver-specific transcription factor LF-B1 contains a highly diverged homeobox DNA binding domain. in Cell 1989
Show all 4 references for ABIN610903
Human Polyclonal WASF2 Primary Antibody for WB - ABIN658461
Cai, Xiao, James, Da, Lin, Liu, Zheng, Zou, Di, Guo, Han, Lu, Cheng, Gao, Zhang: Metastatic potential of lung squamous cell carcinoma associated with HSPC300 through its interaction with WAVE2. in Lung cancer (Amsterdam, Netherlands) 2009
Show all 2 references for ABIN658461
Human Polyclonal WASF2 Primary Antibody for IHC, ELISA - ABIN1451799
Miki, Yamaguchi, Suetsugu, Takenawa: IRSp53 is an essential intermediate between Rac and WAVE in the regulation of membrane ruffling. in Nature 2000
Show all 2 references for ABIN1451799
These findings indicate that inhibition of the Rac1WAVE2Arp2/3 signaling pathway may promote radiosensitivity, which may partially result from the downregulation of CFL1 (show VPS72 Antibodies) in U251 human glioma cells.
SH3BP1 (show SH3BP1 Antibodies) promoted VEGF (show VEGFA Antibodies) secretion via Rac1-WAVE2 signaling, so as to exert an augmentation on cell invasion and microvessel formation.
the MCP1 (show CCL2 Antibodies)-induced cortactin (show CTTN Antibodies) phosphorylation is dependent on PLCb3 (show PLCB3 Antibodies)-mediated PKC (show PRRT2 Antibodies) activation, and siRNA-mediated down-regulation of either of these molecules prevents cortactin (show CTTN Antibodies) interaction with WAVE2
WASp (show WASL Antibodies) and WAVE2 differ in their dynamics and their associated proteins
these results suggest that Arp2 (show ACTR2 Antibodies)/3 and the upstream regulator, WAVE2, are essential co-factors hijacked by HIV for intracellular migration, and may serve as novel targets to prevent HIV transmission.
WAVE2 is down-regulated in gastric cancer
Cortactin (show CTTN Antibodies) has a role as a scaffold for Arp2 (show ACTR2 Antibodies)/3 and WAVE2 at the epithelial zonula adherens
data reveal a critical role for WAVE2 complex in regulation of cellular signaling and epithelial morphogenesis
Identification of an onco-suppressive role of miR (show MLXIP Antibodies)-146a in gastric cancer cells by its reduction of WASF2 expression.
We demonstrate that WAVE2-Arp2 (show ACTR2 Antibodies)/3 is a major nucleator of actin assembly at the zonula adherens and likely acts in response to junctional Rac (show AKT1 Antibodies) signaling
Data show that the primary effect of costimulation blockade was to decrease recruitment of the activator of actin nucleation WAVE2 (Wiskott-Aldrich syndrome protein family member protein 2) and cofilin (actin-severing protein) to F-actin.
The expression of NESH/Abi-3 (show ABI3 Antibodies) caused degradation of endogenous Abi-1 (show ABI1 Antibodies), which led to the formation of a NESH/Abi-3 (show ABI3 Antibodies)-based WAVE2 complex.
This study demonstrated that WAVE2-Abi2 (show ABI2 Antibodies) complex, which controls growth cone activity, is crucial for completing transition from a multipolar to bipolar shape.
Results of the present study show that the nucleation-promoting factors JMY (show JMY Antibodies) and WAVE2 are critical for cytokinesis during development of mouse embryos.
These results identify Wasf2 as a novel target of intermittent PTH administration via the Wnt and phosphoinositide-dependent protein kinase signaling pathways.
The protein and messenger RNA levels of WAVE2 were decreased in aged oocytes, but the levels were normal in caffeine-treated aged oocytes.
mDia1 and WAVE2 are important Src (show SRC Antibodies) homology 3 domain partners of IRSp53 (show BAIAP2 Antibodies) in forming filopodia.
WAVE2 regulates oocyte polarization by regulating meiotic spindle, peripheral positioning, probably via an actin-mediated pathway, and is involved in polar body emission during mouse oocyte meiotic maturation.
sential role for Abi1 (show ABI1 Antibodies) in embryonic survival and WAVE2 complex integrity
WAVE2 works as an A-kinase-anchoring protein (show MYRIP Antibodies) that recruits PKA at membrane protrusions and plays a role in the enlargement of membrane protrusions induced by PKA activation
This gene encodes a member of the Wiskott-Aldrich syndrome protein family. The gene product is a protein that forms a multiprotein complex that links receptor kinases and actin. Binding to actin occurs through a C-terminal verprolin homology domain in all family members. The multiprotein complex serves to tranduce signals that involve changes in cell shape, motility or function. The published map location (PMID:10381382) has been changed based on recent genomic sequence comparisons, which indicate that the expressed gene is located on chromosome 1, and a pseudogene may be located on chromosome X. Two transcript variants encoding different isoforms have been found for this gene.
WAS protein family, member 2
, wiskott-Aldrich syndrome protein family member 2
, WASP family Verprolin-homologous protein 2
, WASP family protein member 2
, WASP family protein member 4
, protein WAVE-2
, putative Wiskott-Aldrich syndrome protein family member 4
, suppressor of cyclic-AMP receptor (WASP-family)
, verprolin homology domain-containing protein 2