WASF2 antibody (Internal Region)

Catalog No. ABIN6280913

Product Details anti-WASF2 Antibody

Target: WASF2 (WAS Protein Family, Member 2 (WASF2))

Binding Specificity: AA 110-190, Internal Region

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This WASF2 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purpose: WAVE2 is a protein encoded by the WASF2 gene which is approximately 54,2 kDa. WAVE2 is localised to the cytoplasm and is involved in regulation of actin dynamics for phagocytic cup formation, innate immune system, signalling by Rho GTPases and RET signalling. It is a downstream effector molecule involved in the transmission of signals from tyrosine kinase receptors and small GTPases to the actin cytoskeleton and is expressed in all tissues. Mutations in the WASF2 gene may result in Wiskott-Aldrich syndrome and depression. STJ96263 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This polyclonal antibody detects endogenous levels of WAVE2 protein.

Specificity: WAVE2 Polyclonal Antibody detects endogenous levels of WAVE2 protein.

Characteristics: Rabbit polyclonal to WAVE2.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human WAVE2

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000
IHC 1:100-1:300
ELISA 1:5000

Comment:

Expressed in all tissues with strongest expression in placenta, lung, and peripheral blood leukocytes, but not in skeletal muscle.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C, and avoid repeat freeze-thaw cycles.

Target Details for WASF2

Target: WASF2 (WAS Protein Family, Member 2 (WASF2))

Alternative Name: WAVE2 (WASF2 Products)

Synonyms: zgc:56010 antibody, WASF2 antibody, scar2 antibody, wave2 antibody, IMD2 antibody, SCAR2 antibody, WASF4 antibody, WAVE2 antibody, dJ393P12.2 antibody, AW742646 antibody, D4Ertd13e antibody, WAS protein family, member 2 antibody, WAS protein family member 2 antibody, WAS protein family member 2 L homeolog antibody, wasf2 antibody, WASF2 antibody, wasf2.L antibody, Wasf2 antibody

Molecular Weight: 55 kDa

Gene ID: 10163

UniProt: Q9Y6W5

Pathways: RTK Signaling