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Browse our CLIC5 Proteins (CLIC5)

Full name:
Chloride Intracellular Channel 5 Proteins (CLIC5)
On www.antibodies-online.com are 7 Chloride Intracellular Channel 5 (CLIC5) Proteins from 4 different suppliers available. Additionally we are shipping CLIC5 Antibodies (42) and CLIC5 Kits (1) and many more products for this protein. A total of 56 CLIC5 products are currently listed.
Synonyms:
5730531E12Rik, B330005L24, CLIC5, Gm322, im:6907594, jbg, MGC68985, MST130, MSTP130, zgc:77538, zgc:101827
list all proteins Gene Name GeneID UniProt
CLIC5 53405 Q9NZA1
CLIC5 224796 Q8BXK9
Rat CLIC5 CLIC5 94272 Q9EPT8

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CLIC5 Proteins (CLIC5) by Origin

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More Proteins for CLIC5 Interaction Partners

Human Chloride Intracellular Channel 5 (CLIC5) interaction partners

  1. EZR (show EZR Proteins), CLIC5 and PODXL (show PODXL Proteins) are overexpressed in hepatocellular carcinoma and may have a role in cell migration and invasiveness

  2. The mechanism of CLIC5A action involves clustered plasma membrane phosphatidylinositol 4,5-bisphosphate accumulation, in turn facilitating ezrin activation and actin-dependent cell surface remodeling.

  3. CLIC5 is a novel gene involved in progressive hearing impairment, vestibular and possibly mild renal dysfunction.

  4. CLIC5A colocalizes with ezrin (show EZR Proteins) and podocalyxin (show PODXL Proteins) in podocytes and is required for the development/maintenance of the proper glomerular endothelial cell and podocyte architecture.

  5. association with Golgi apparatus AKAP350

  6. CLIC-5A has a role as a chloride channel in vitro and binds to cortical actin cytoskeleton

  7. CLIC5 was demonstrated in cultured lymphoblasts.

  8. Data showed that CLIC1 and CLIC5, but not CLIC4, were strongly and reversibly inhibited (or inactivated) by F-actin.

Pig (Porcine) Chloride Intracellular Channel 5 (CLIC5) interaction partners

  1. results suggest that CLIC5 might be a crucial regulator of adipose accumulation in skeletal muscle of pigs

Cow (Bovine) Chloride Intracellular Channel 5 (CLIC5) interaction partners

  1. CLIC5A colocalizes with ezrin (show EZR Proteins) and podocalyxin (show PODXL Proteins) in podocytes and is required for the development/maintenance of the proper glomerular endothelial cell and podocyte architecture.

Mouse (Murine) Chloride Intracellular Channel 5 (CLIC5) interaction partners

  1. Augmented hypertension-induced glomerular capillary injury in mice lacking CLIC5 results from abrogation of Rac1-dependent Pak and ezrin activation, perhaps reducing the tensile strength of the podocyte actin cytoskeleton.

  2. The mechanism of CLIC5A action involves clustered plasma membrane phosphatidylinositol 4,5-bisphosphate accumulation, in turn facilitating ezrin activation and actin-dependent cell surface remodeling.

  3. Biochemical assays showed interaction of CLIC5 with ERM (show ETV5 Proteins) proteins, TPRN (show TPRN Proteins), and possibly myosin VI (MYO6 (show MYO6 Proteins)). In addition, CLIC5 and RDX (show RDX Proteins) failed to localize normally in fused stereocilia of MYO6 (show MYO6 Proteins) mutant mice

  4. miR (show MLXIP Proteins)-96 and miR (show MLXIP Proteins)-182 regulate the in vivo expression of CLIC5 in mouse inner ear hair cells

  5. Study identifies CLIC5 as a new component that is enriched in and necessary for foot process integrity and podocyte function in vivo.

  6. CLIC5 disrupts proliferation of C2C12 cells and is involved in the differentiation of myoblasts by enhancing the protein expression level of MyHC, myogenin (show MYOG Proteins) and desmin (show DES Proteins).

  7. Clic5 mutant mice are resistant to diet-induced obesity.

  8. CLIC5A colocalizes with ezrin (show EZR Proteins) and podocalyxin (show PODXL Proteins) in podocytes and is required for the development/maintenance of the proper glomerular endothelial cell and podocyte architecture.

  9. CLIC5 associates with radixin in hair cell stereocilia and may help form or stabilize connections between the plasma membrane and the filamentous actin core.

CLIC5 Protein Profile

Protein Summary

This gene encodes a member of the chloride intracellular channel (CLIC) family of chloride ion channels. The encoded protein associates with actin-based cytoskeletal structures and may play a role in multiple processes including hair cell stereocilia formation, myoblast proliferation and glomerular podocyte and endothelial cell maintenance. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Alternative names and synonyms associated with CLIC5

  • chloride intracellular channel 5 (clic5)
  • chloride intracellular channel 5 (CLIC5)
  • chloride intracellular channel 5a (clic5a)
  • chloride intracellular channel 5 (Clic5)
  • chloride intracellular channel 5b (clic5b)
  • 5730531E12Rik protein
  • B330005L24 protein
  • CLIC5 protein
  • Gm322 protein
  • im:6907594 protein
  • jbg protein
  • MGC68985 protein
  • MST130 protein
  • MSTP130 protein
  • zgc:77538 protein
  • zgc:101827 protein

Protein level used designations for CLIC5

chloride intracellular channel 5 , chloride intracellular channel protein 6 , chloride intracellular channel protein 5-like , chloride intracellular channel protein 5 , chloride channel protein p64 , chlorine channel protein p64

GENE ID SPECIES
380025 Xenopus laevis
462739 Pan troglodytes
492513 Danio rerio
703565 Macaca mulatta
100055661 Equus caballus
100407287 Callithrix jacchus
100453932 Pongo abelii
100470286 Ailuropoda melanoleuca
100587743 Nomascus leucogenys
422054 Gallus gallus
53405 Homo sapiens
481822 Canis lupus familiaris
100154589 Sus scrofa
281696 Bos taurus
224796 Mus musculus
94272 Rattus norvegicus
734242 Xenopus laevis
405833 Danio rerio
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