CLIC5 Protein (AA 1-251) (His tag)

Catalog No. ABIN7504921

Product Details

Target: CLIC5 (Chloride Intracellular Channel 5 (CLIC5))

Protein Type: Recombinant

Protein Characteristics: AA 1-251

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This CLIC5 protein is labelled with His tag.

Sequence: Met 1-Ser251

Characteristics: Recombinant Human Chloride Intracellular Channel Protein 5 is produced by our E.coli expression system and the target gene encoding Met1-Ser251 is expressed with a 6His tag at the N-terminus.

Purity: >95 % as determined by reducing SDS-PAGE.

Endotoxin Level: <1.0 EU per μg of the protein as determined by the LAL method.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Expiry Date: 12 months

Target Details

Target: CLIC5 (Chloride Intracellular Channel 5 (CLIC5))

Alternative Name: CLIC5 (CLIC5 Products)

Synonyms: MST130 Protein, MSTP130 Protein, 5730531E12Rik Protein, B330005L24 Protein, Gm322 Protein, jbg Protein, clic5 Protein, im:6907594 Protein, zgc:77538 Protein, CLIC5 Protein, zgc:101827 Protein, chloride intracellular channel 5 Protein, chloride intracellular channel 5b Protein, chloride intracellular channel 5a Protein, chloride intracellular channel 5 L homeolog Protein, CLIC5 Protein, Clic5 Protein, clic5b Protein, clic5a Protein, clic5.L Protein

Background:

Background: Chloride Intracellular Channel Protein 5 (CLIC5) is a single-pass membrane protein which belongs to the chloride channel CLIC family. It contains one GST C-terminal domain. Chloride intracellular channels are involved in chloride ion transport within various subcellular compartments. CLIC5 can insert into membranes and form selective ion channels regulated by actin that may transport chloride ions. It may play a role in the regulation of transepithelial ion absorption and secretion. CLIC5 specifically associates with the cytoskeleton of placenta microvilli. CLIC5 is required for the development and/or maintenance of the proper glomerular endothelial cell and podocyte architecture.

Synonym: Chloride Intracellular Channel Protein 5, CLIC5

Molecular Weight: 30.3 kDa

UniProt: Q9NZA1

Pathways: Sensory Perception of Sound