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anti-Human MPV17L Antibodies:
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Guinea Pig Polyclonal MPV17L Primary Antibody for WB - ABIN2786323
Iida, Yasuda, Tsubota, Takatsuka, Matsuki, Kishi: Human Mpv17-like protein is localized in peroxisomes and regulates expression of antioxidant enzymes. in Biochemical and biophysical research communications 2006
these observations suggest that M-LPH is involved in the maintenance of mtDNA and protects cells from mitochondrial dysfunction.
In mice, M-LPs (show TLR4 Antibodies) is expressed exclusively in kidneys after 6 weeks. Transfection with M-LPS (show TLR4 Antibodies) up-regulates SOD2 (show SOD2 Antibodies) and down-regulates cellular glutathione peroxidase (Gpx1 (show GPX1 Antibodies)) and plasma glutathione peroxidase (Gpx3 (show GPX3 Antibodies)) gene expression
identify Mpv17l as a unique interacting protein and regulator of HtrA2 (show HTRA2 Antibodies) protease mediating antioxidant and antiapoptotic function in mitochondria
Participates in reactive oxygen species metablism by up- or down-regulation of the genes of antioxidant enzymes (By similarity).
Mpv17 transgene, kidney disease mutant-like
, protein Mpv17
, mpv17-like protein
, MPV17 mitochondrial membrane protein-like
, M-LP homolog
, Mpv17-like protein type 1
, Mpv17-like protein type 2