Browse our anti-SORL1 (SORL1) Antibodies

Full name:
anti-Sortilin-Related Receptor, L(DLR Class) A Repeats Containing Antibodies (SORL1)
On www.antibodies-online.com are 100 Sortilin-Related Receptor, L(DLR Class) A Repeats Containing (SORL1) Antibodies from 19 different suppliers available. Additionally we are shipping SORL1 Kits (10) and SORL1 Proteins (2) and many more products for this protein. A total of 116 SORL1 products are currently listed.
Synonyms:
2900010L19Rik, AI596264, AW261561, C11orf32, gp250, Lr11, LRP9, mSorLA, RGD619914, SORL1, SorLA, SorLA-1
list all antibodies Gene Name GeneID UniProt
SORL1 6653 Q92673
SORL1 20660 O88307
SORL1 300652  

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Top referenced anti-SORL1 Antibodies

  1. Human Polyclonal SORL1 Primary Antibody for EIA, IP - ABIN493474 : Taira, Bujo, Hirayama, Yamazaki, Kanaki, Takahashi, Ishii, Miida, Schneider, Saito: LR11, a mosaic LDL receptor family member, mediates the uptake of ApoE-rich lipoproteins in vitro. in Arteriosclerosis, thrombosis, and vascular biology 2001 (PubMed)
    Show all 3 references for 493474

  2. Human Monoclonal SORL1 Primary Antibody for ICC, IHC - ABIN1724674 : Scherzer, Offe, Gearing, Rees, Fang, Heilman, Schaller, Bujo, Levey, Lah: Loss of apolipoprotein E receptor LR11 in Alzheimer disease. in Archives of neurology 2004 (PubMed)
    Show all 3 references for 1724674

  3. Human Monoclonal SORL1 Primary Antibody for ELISA, WB - ABIN1724683 : Gabrielsson, Olofsson, Sjögren, Jernås, Elander, Lönn, Rudemo, Carlsson: Evaluation of reference genes for studies of gene expression in human adipose tissue. in Obesity research 2005 (PubMed)
    Show all 3 references for 1724683

  4. Human Monoclonal SORL1 Primary Antibody for IHC (fro), FACS - ABIN1109103 : Shah, Yu: sorLA: sorting out APP. in Molecular interventions 2006 (PubMed)
    Show all 3 references for 1109103

  5. Human Monoclonal SORL1 Primary Antibody for IF, WB - ABIN968682 : Jacobsen, Madsen, Moestrup, Lund, Tommerup, Nykjaer, Sottrup-Jensen, Gliemann, Petersen: Molecular characterization of a novel human hybrid-type receptor that binds the alpha2-macroglobulin receptor-associated protein. in The Journal of biological chemistry 1997 (PubMed)
    Show all 3 references for 968682

  6. Fly (Calliphora) Monoclonal SORL1 Primary Antibody for IHC, WB - ABIN968899 : Posse De Chaves, Vance, Campenot, Kiss, Vance: Uptake of lipoproteins for axonal growth of sympathetic neurons. in The Journal of biological chemistry 2000 (PubMed)
    Show all 3 references for 968899

  7. Mouse (Murine) Polyclonal SORL1 Primary Antibody for ELISA, WB - ABIN184579 : Jacobsen, Madsen, Jacobsen, Nielsen, Gliemann, Petersen: Activation and functional characterization of the mosaic receptor SorLA/LR11. in The Journal of biological chemistry 2001 (PubMed)
    Show all 2 references for 184579

More Antibodies against SORL1 Interaction Partners

Human Sortilin-Related Receptor, L(DLR Class) A Repeats Containing (SORL1) interaction partners

  1. Analysis of the molecular mechanism for the association of SORL1 with obesity: there is a genetic link between neurodegeneration and metabolism that converges on the receptor SORLA

  2. This review will provide a comprehensive overview of the evidence implicating SORLA-mediated protein sorting in neurodegenerative processes, and how receptor gene variants in the human population impair functional receptor expression in sporadic but possibly also in autosomal-dominant forms of Alzheimer's disease.

  3. SorLA ectodomain, released from the cell membrane upon enzymatic cleavage of full-length SorLA, may act as an IL-6 (show IL6 Antibodies) carrier protein that stabilizes IL-6 (show IL6 Antibodies) and its capacity for trans signaling.

  4. observed a 1.5-fold enrichment of rare non-synonymous variants of sortilin-related receptor 1 in Alzheimer's disease patients

  5. This review article discusses the molecular mechanisms that govern sorting of SORLA and its cargo in multiple cell types, and why genetic defects in this receptor results in devastating diseases. [review]

  6. The presence of rare coding variants in SORL1 in three different European American cohorts: early-onset, late-onset AD (LOAD) and familial LOAD, was examined.

  7. sLR11 levels in bile may be indicative of cancer cell conditions and may serve as potential novel biomarker in patients with BTC (show BTC Antibodies) and PC

  8. SORL1 protein is involved with late onset Alzheimer's disease. [review]

  9. The DNA methylation (show HELLS Antibodies) of the SORL1 5'-flanking region may significantly influence the manifestation of mild cognitive impairment in T2 Diabetes mellitus, and might be associated with its neurocognitive presentation.

  10. Findings provide evidence that sortilin (show SORT1 Antibodies) receptor 1 rs3824968 modulates regional gray matter volume and is associated with brain trajectory during the adult lifespan.

Mouse (Murine) Sortilin-Related Receptor, L(DLR Class) A Repeats Containing (SORL1) interaction partners

  1. Analysis of the molecular mechanism for the association of SORL1 with obesity: there is a genetic link between neurodegeneration and metabolism that converges on the receptor SORLA

  2. SorLA ectodomain, released from the cell membrane upon enzymatic cleavage of full-length SorLA, may act as an IL-6 (show IL6 Antibodies) carrier protein that stabilizes IL-6 (show IL6 Antibodies) and its capacity for trans signaling.

  3. We identify binding and trafficking interactions between two of these factors, SORLA and SNX27 (show SNX27 Antibodies), and demonstrate that SNX27 (show SNX27 Antibodies) can direct trafficking of SORLA and the Abeta (show APP Antibodies) precursor APP (show APP Antibodies) to the cell surface to limit the production of Abeta (show APP Antibodies). Diversion APP (show APP Antibodies) to the cell surface through modulation of this molecular complex may represent a complimentary strategy for future development in AD treatment.

  4. LR11 regulated vascular smooth muscle cell proliferation during the progression of hypoxia-induced medial thickening in mice.

  5. Therefore, SORL1 activation by 6-shogaol provides neuronal cell survival through the inhibition of Abeta (show APP Antibodies) production. These results indicate that 6-shogaol should be regarded as an SORL1 activator and a potential preventive agent for the treatment of AD.

  6. Data strongly suggest an involvement of LR11 in mediating the harmful effects of a high-fat diet on CVD progression.

  7. Mice lacking LR11 are protected from diet-induced obesity associated with an increased browning of white adipose tissue and hypermetabolism.

  8. using massively parallel reporter assays, we dissect the enhancer activity of three liver eExons (SORL1 exon 17, TRAF3IP2 (show TRAF3IP2 Antibodies) exon 2, PPARG (show PPARG Antibodies) exon 6) at single nucleotide resolution in the mouse liver

  9. Data indicate that activation of alpha(2A) adrenergic receptor (alpha(2A)AR (show ADRA2A Antibodies)) signaling disrupts transgenic amyloid precursor protein (APP (show APP Antibodies)) interaction with sorting-related receptor with A repeat (SorLA) in cells and brain.

  10. SORLA-mediated trafficking of TrkB (show NTRK2 Antibodies) enhances the response of neurons to BDNF (show BDNF Antibodies).

SORL1 Antigen Profile

Antigen Summary

This gene encodes a mosaic protein that belongs to at least two families: the vacuolar protein sorting 10 (VPS10) domain-containing receptor family, and the low density lipoprotein receptor (LDLR) family. The encoded protein also contains fibronectin type III repeats and an epidermal growth factor repeat. The encoded protein is translated as a preproprotein and likely plays roles in endocytosis and sorting. There may be an association between expression of this locus and Alzheimer's Disease.

Alternative names and synonyms associated with SORL1

  • sortilin-related receptor, L(DLR class) A repeats containing (sorl1) antibody
  • sortilin-related receptor, L(DLR class) A repeats-containing (SORL1) antibody
  • sortilin-related receptor, L(DLR class) A repeats-containing (LOC100226349) antibody
  • sortilin-related receptor, L(DLR class) A repeats-containing (sorl1) antibody
  • sortilin-related receptor, L(DLR class) A repeats containing (SORL1) antibody
  • sortilin-related receptor, LDLR class A repeats-containing (Sorl1) antibody
  • 2900010L19Rik antibody
  • AI596264 antibody
  • AW261561 antibody
  • C11orf32 antibody
  • gp250 antibody
  • Lr11 antibody
  • LRP9 antibody
  • mSorLA antibody
  • RGD619914 antibody
  • SORL1 antibody
  • SorLA antibody
  • SorLA-1 antibody

Protein level used designations for SORL1

sortilin-related receptor, L(DLR class) A repeats containing , sortilin-related receptor, L(DLR class) A repeats-containing , sortilin-related receptor-like , LDLR relative with 11 ligand-binding repeats , low-density lipoprotein receptor relative with 11 ligand-binding repeats , mosaic protein LR11 , sortilin-related receptor , sorting protein-related receptor containing LDLR class A repeats , LR11 , sorLA , sorLA-1

GENE ID SPECIES
100566946 Anolis carolinensis
582560 Strongylocentrotus purpuratus
713011 Macaca mulatta
100024063 Monodelphis domestica
100071572 Equus caballus
100073504 Ornithorhynchus anatinus
100226349 Taeniopygia guttata
100490681 Xenopus (Silurana) tropicalis
100524036 Sus scrofa
6653 Homo sapiens
479408 Canis lupus familiaris
533166 Bos taurus
395998 Gallus gallus
100009378 Oryctolagus cuniculus
20660 Mus musculus
300652 Rattus norvegicus
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