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SORL1 Products

(Sortilin-Related Receptor, L(DLR Class) A Repeats Containing (SORL1))
This gene encodes a mosaic protein that belongs to at least two families: the vacuolar protein sorting 10 (VPS10) domain-containing receptor family, and the low density lipoprotein receptor (LDLR) family. The encoded protein also contains fibronectin type III repeats and an epidermal growth factor repeat. The encoded protein is translated as a preproprotein and likely plays roles in endocytosis and sorting. There may be an association between expression of this locus and Alzheimer's Disease.[provided by RefSeq, Sep 2010].

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Featured SORL1 Categories

SORL1 Antibodies

High quality antibodies with extensive validation data.

SORL1 ELISA Kits

Reliable ELISA kits for a wide range of species.

SORL1 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended SORL1 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rat
Application FACS, IHC, WB
Validations
  • (5)
Cat. No. ABIN7043770
Quantity 0.2 mL
Datasheet Datasheet
Reactivity Human
Application ELISA, IF
Validations
  • (1)
  • (3)
Cat. No. ABIN184579
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application ELISA, ICC, IF (cc), IF (p), IHC (fro), IHC (p)
Validations
  • (2)
Cat. No. ABIN1387514
Quantity 100 μL
Datasheet Datasheet

Recommended SORL1 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6970374
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6973562
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6229260
Quantity 96 tests
Datasheet Datasheet

Recommended SORL1 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1320969
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN2751569
Quantity 5 applications
Datasheet Datasheet

Latest Publications for our SORL1 products

Yajima, Tokutake, Koyama, Kasuga, Tezuka, Nishizawa, Ikeuchi: "ApoE-isoform-dependent cellular uptake of amyloid-β is mediated by lipoprotein receptor LR11/SorLA." in: Biochemical and biophysical research communications, Vol. 456, Issue 1, pp. 482-8, (2014) (PubMed).

Kim, Lee, Lee, Kim, Song, Huh, Lee, Kim, Kim, Hong, Shim, Chang: "Implication of mouse Vps26b-Vps29-Vps35 retromer complex in sortilin trafficking." in: Biochemical and biophysical research communications, Vol. 403, Issue 2, pp. 167-71, (2010) (PubMed).

Doering, Kane, Hsiao, Yao, Shi, Slowik, Dhagat, Scott, Ault, Page-McCaw, Ferland: "Species differences in the expression of Ahi1, a protein implicated in the neurodevelopmental disorder Joubert syndrome, with preferential accumulation to stigmoid bodies." in: The Journal of comparative neurology, Vol. 511, Issue 2, pp. 238-56, (2008) (PubMed).

Rogaeva, Meng, Lee, Gu, Kawarai, Zou, Katayama, Baldwin, Cheng, Hasegawa, Chen, Shibata, Lunetta, Pardossi-Piquard, Bohm, Wakutani, Cupples, Cuenco, Green, Pinessi, Rainero, Sorbi, Bruni, Duara et al.: "The neuronal sortilin-related receptor SORL1 is genetically associated with Alzheimer disease. ..." in: Nature genetics, Vol. 39, Issue 2, pp. 168-77, (2007) (PubMed).

Shah, Yu: "sorLA: sorting out APP." in: Molecular interventions, Vol. 6, Issue 2, pp. 74-6, 58, (2006) (PubMed).

Gabrielsson, Olofsson, Sjögren, Jernås, Elander, Lönn, Rudemo, Carlsson: "Evaluation of reference genes for studies of gene expression in human adipose tissue." in: Obesity research, Vol. 13, Issue 4, pp. 649-52, (2005) (PubMed).

Scherzer, Offe, Gearing, Rees, Fang, Heilman, Schaller, Bujo, Levey, Lah: "Loss of apolipoprotein E receptor LR11 in Alzheimer disease." in: Archives of neurology, Vol. 61, Issue 8, pp. 1200-5, (2004) (PubMed).

Jacobsen, Madsen, Jacobsen, Nielsen, Gliemann, Petersen: "Activation and functional characterization of the mosaic receptor SorLA/LR11." in: The Journal of biological chemistry, Vol. 276, Issue 25, pp. 22788-96, (2001) (PubMed).

Posse De Chaves, Vance, Campenot, Kiss, Vance: "Uptake of lipoproteins for axonal growth of sympathetic neurons." in: The Journal of biological chemistry, Vol. 275, Issue 26, pp. 19883-90, (2000) (PubMed).

Jacobsen, Madsen, Moestrup, Lund, Tommerup, Nykjaer, Sottrup-Jensen, Gliemann, Petersen: "Molecular characterization of a novel human hybrid-type receptor that binds the alpha2-macroglobulin receptor-associated protein." in: The Journal of biological chemistry, Vol. 271, Issue 49, pp. 31379-83, (1997) (PubMed).

Synonyms and alternative names related to SORL1

sortilin related receptor 1 (sorl1), sortilin-related receptor (LOC582560), sortilin related receptor 1 (SORL1), sortilin-related receptor, L(DLR class) A repeats containing (sorl1), sortilin-related receptor, L(DLR class) A repeats-containing (SORL1), sortilin-related receptor, LDLR class A repeats-containing (Sorl1), sortilin related receptor 1 (Sorl1), 2900010L19Rik, AI596264, AW261561, C11orf32, gp250, LR11, Lr11, LRP9, mSorLA, RGD619914, SORL1, SORLA, SorLA, SorLA-1

Protein level used designations for SORL1

  • sortilin-related receptor, L(DLR class) A repeats containing
  • sortilin-related receptor, L(DLR class) A repeats-containing
  • sortilin-related receptor-like
  • LDLR relative with 11 ligand-binding repeats
  • low-density lipoprotein receptor relative with 11 ligand-binding repeats
  • mosaic protein LR11
  • sortilin-related receptor
  • sorting protein-related receptor containing LDLR class A repeats
  • LR11
  • sorLA
  • sorLA-1
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