anti-Human Hydroxysteroid (11-Beta) Dehydrogenase 2 antibody for Western Blotting

Recommended Hydroxysteroid (11-Beta) Dehydrogenase 2 Antibody (supplied by: Log in to see )

Antigen
Hydroxysteroid (11-Beta) Dehydrogenase 2 (HSD11B2) Antibodies
  • MGC81883
  • 11-HSD2
  • AME
  • AME1
  • HSD11K
  • HSD2
  • SDR9C3
  • 11HSD2
  • HSD11B2
  • hydroxysteroid (11-beta) dehydrogenase 2
  • hydroxysteroid 11-beta dehydrogenase 2
  • NAD-dependent 11-beta-hydroxysteroid dehydrogenase
  • hsd11b2
  • HSD11B2
  • Hsd11b2
  • HSD11K
Epitope
N-Term
15
15
10
10
10
8
8
8
8
4
4
2
1
1
1
Reactivity
Cow (Bovine), Guinea Pig, Horse (Equine), Human, Mouse (Murine), Rabbit, Rat (Rattus), Sheep (Ovine)
87
57
51
1
1
1
1
1
1
1
1
1
1
Host
Rabbit
90
4
2
1
Clonality
Polyclonal
Conjugate
Un-conjugated
4
4
4
2
2
2
2
2
2
2
2
2
2
2
2
2
2
Application
Western Blotting (WB)
69
32
26
26
19
17
4
3
1
Options
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Catalog No. ABIN2776772
$ 289.00
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
3.1099 ABIN3043846 IHC (p) WB Rabbit IgG AA 277-309, C-Term Log in to see Polyclonal
3.1099 ABIN950176 FACS IHC (p) WB Rabbit Ig AA 284-314, Middle Region Log in to see Polyclonal 1
3.1099 ABIN2736918 IHC WB Rabbit IgG Log in to see Polyclonal
3.1099 ABIN653721 FACS IHC (p) WB Rabbit Ig AA 277-306, Center Log in to see Polyclonal
3.1099 ABIN2458581 ELISA WB Rabbit Log in to see Polyclonal
3.1099 ABIN262208 WB Chicken Log in to see Polyclonal
3.1099 ABIN2468177 WB Chicken AA 181-405 Log in to see Polyclonal
3.1099 ABIN631485 WB Rabbit Log in to see Polyclonal
3.1099 ABIN4890172 WB Rabbit N-Term Log in to see Polyclonal
3.1099 ABIN4319869 IHC IHC (p) WB Rabbit Log in to see Polyclonal
3.1099 ABIN516705 WB Mouse AA 1-405, full length Log in to see Polyclonal
3.1099 ABIN516707 IP WB Rabbit AA 1-405, full length Log in to see Polyclonal
3.1099 ABIN516706 WB Mouse AA 1-405, full length Log in to see Polyclonal
3.1099 ABIN516708 WB Rabbit AA 1-405, full length Log in to see Polyclonal
1 ABIN701680 IF (p) IHC (p) WB Rabbit IgG AA 170-220 Log in to see Polyclonal 1
1 ABIN5611419 IHC (p) WB Rabbit IgG AA 25-40 Log in to see Polyclonal
1 ABIN447989 IHC (p) WB Rabbit IgG AA 25-40 Log in to see Polyclonal
1 ABIN320631 WB Rabbit IgG N-Term Log in to see Polyclonal
1 ABIN2859384 IHC (p) WB Rabbit IgG AA 25-40 Log in to see Polyclonal
1 ABIN701689 IHC (p) WB HRP Rabbit IgG AA 170-220 Log in to see Polyclonal

General

Antigen Hydroxysteroid (11-Beta) Dehydrogenase 2 (HSD11B2) Antibodies
Epitope N-Term
(15), (15), (10), (10), (10), (8), (8), (8), (8), (4), (4), (2), (1), (1), (1)
Reactivity Cow (Bovine), Guinea Pig, Horse (Equine), Human, Mouse (Murine), Rabbit, Rat (Rattus), Sheep (Ovine)
(87), (57), (51), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Host Rabbit
(90), (4), (2), (1)
Clonality
Polyclonal
Conjugate Un-conjugated
(4), (4), (4), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2)
Application Western Blotting (WB)
(69), (32), (26), (26), (19), (17), (4), (3), (1)
Pubmed 1 reference available
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Product details

Target details Application Details Handling References Images
Blocking Peptide Blocking peptide for this product available: ABIN978258
Sequence ERWPWPSGGA WLLVAARALL QLLRSDLRLG RPLLAALALL AALDWLCQRL
Predicted Reactivity Cow: 100%, Guinea Pig: 100%, Horse: 92%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%
Characteristics This is a rabbit polyclonal antibody against HSD11B2. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Immunogen The immunogen is a synthetic peptide directed towards the N terminal region of human HSD11B2

Target details

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Antigen
Alternative Name HSD11B2 (HSD11B2 Antibody Abstract)
Background HSD11B2 catalyzes the conversion of cortisol to the inactive metabolite cortisone. It modulates intracellular glucocorticoid levels, thus protecting the nonselective mineralocorticoid receptor from occupation by glucocorticoids.
Alias Symbols: AME, AME1, HSD11K, HSD2, SDR9C3
Protein Interaction Partner: KAT2B, HDAC1, KAT2A, CTBP1,
Protein Size: 44
Molecular Weight 45 kDa
Gene ID 3291
NCBI Accession NM_000196, NP_000187
UniProt P80365
Research Area Cancer, Hormones
Pathways Steroid Hormone Biosynthesis, Regulation of Systemic Arterial Blood Pressure by Hormones

Application Details

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Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 44 AA

Restrictions For Research Use only

Handling

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Format Liquid
Concentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References

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Background publications

Subtil-Rodríguez, Millán-Ariño, Quiles, Ballaré, Beato, Jordan: "Progesterone induction of the 11beta-hydroxysteroid dehydrogenase type 2 promoter in breast cancer cells involves coordinated recruitment of STAT5A and progesterone receptor to a distal enhancer and polymerase tracking." in: Molecular and cellular biology, Vol. 28, Issue 11, pp. 3830-49, 2008

Images

Product details Target details Application Details Handling References back to top
Supplier Images
Western Blotting (WB) image for anti-Hydroxysteroid (11-Beta) Dehydrogenase 2 (HSD11B2) (N-Term) antibody (ABIN2776772) anti-Hydroxysteroid (11-Beta) Dehydrogenase 2 (HSD11B2) (N-Term) antibody