Browse our Cholinergic Receptor, Nicotinic, alpha 3 (Neuronal) Proteins (CHRNA3)

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Cholinergic Receptor, Nicotinic, alpha 3 (Neuronal) Proteins (CHRNA3)
On www.antibodies-online.com are 9 Cholinergic Receptor, Nicotinic, alpha 3 (Neuronal) (CHRNA3) Proteins from 3 different suppliers available. Additionally we are shipping Cholinergic Receptor, Nicotinic, alpha 3 (Neuronal) Antibodies (70) and Cholinergic Receptor, Nicotinic, alpha 3 (Neuronal) Kits (4) and many more products for this protein. A total of 89 Cholinergic Receptor, Nicotinic, alpha 3 (Neuronal) products are currently listed.
Synonyms:
(a)3, A730007P14Rik, Acra-3, Acra3, LNCR2, NACHRA3, PAOD2
list all proteins Gene Name GeneID UniProt
CHRNA3 1136 P32297
CHRNA3 110834 Q8R4G9
Rat CHRNA3 CHRNA3 25101  

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Cholinergic Receptor, Nicotinic, alpha 3 (Neuronal) Proteins (CHRNA3) by Origin

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More Proteins for Cholinergic Receptor, Nicotinic, alpha 3 (Neuronal) Interaction Partners

Human Cholinergic Receptor, Nicotinic, alpha 3 (Neuronal) (CHRNA3) interaction partners

  1. The results of this study suggests a pleiotropic role of Chr15q25 CHRNA5-CHRNA3-CHRNB4 gene cluster with complex influences in ADHD, tobacco smoking and cognitive performance.

  2. both rs578776 and rs938682 of CHRNA3 were significantly associated with the susceptibility of lung cancer.

  3. the association of 3 selected single-nucleotide polymorphisms (CHRNA3 rs1051730, rs6495308, and CHRNA5 rs55853898) with nicotine dependence in an isolated population of Kashubians from Poland, is reported.

  4. CHRNA3 rs1051730 (G > A) and AGPHD1 rs8034191 (A > G) were more susceptible to lung cancers than noncarriers.

  5. focus on the CHRNA5/A3/B4 gene cluster and its role in nicotine dependence (review)

  6. At CHRNA3, allele G of rs3743078 was associated with increased nicotine craving.

  7. Our data suggest that gene variance in the CHRNA5 (show CHRNA5 Proteins)-CHRNA3-CHRNB4 cluster is associated with an increased risk of death, incidence of COPD (show ARCN1 Proteins) and tobacco-related cancer in smokers.

  8. two SNPs (rs6495308 and rs11072768) in CHRNA5-A3-B4 have a indirect effect on lung cancer through smoking behaviors

  9. CHRNA3 - candidate gene for Chronic Obstructive Pulmonary Disease identified by Genome-wide association studies.

  10. Data suggest that CHRNA5-A3-B4 gene variants do not exhibit a robust association with smoking cessation and are unlikely to be useful for clinically optimizing smoking cessation pharmacotherapy for Caucasian smokers.

Cow (Bovine) Cholinergic Receptor, Nicotinic, alpha 3 (Neuronal) (CHRNA3) interaction partners

  1. Data show that a basic residue at position 210 of alpha3 subunit decreases the assembly of heteromeric neuronal alpha3beta4 nicotinic ACh (show FGFR3 Proteins) receptors.

Pig (Porcine) Cholinergic Receptor, Nicotinic, alpha 3 (Neuronal) (CHRNA3) interaction partners

  1. Sympathetic alpha3beta2-nAChRs (CHRNA3/CHRNB2) mediate basilar artery neurogenic nitrergic vasodilation in swine.

Mouse (Murine) Cholinergic Receptor, Nicotinic, alpha 3 (Neuronal) (CHRNA3) interaction partners

  1. neuroinflammation is sufficient to provoke the decrease of a7 and a4b2 nAChRs, Ab42 accumulation and memory impairment in mice and a7(1-208) nAChR (show CHRNA4 Proteins)-specific antibodies can cause inflammation of the brain with symptoms typical for Alzheimer disease

  2. The alpha3beta4* nicotinic ACh (show FGFR3 Proteins) receptor subtype mediates physical dependence to morphine

  3. The present findings suggest that its thymic production and/or release are under cholinergic control involving nAChR (show CHRNA4 Proteins) containing the alpha3-subunit.

  4. Downregulation of nAChR (show CHRNA4 Proteins) subunit and PSD-93 (show DLG2 Proteins) expression after cavernous nerve injury, or even manipulation, could interrupt synaptic transmission within the MPG (show MPG Proteins) and thus contribute to the loss of neural control of urogenital organs after pelvic surgeries.

  5. findings suggest an important role for the a3b4* nAChR (show CHRNA4 Proteins) subtype in nicotine reward and physical aspects of the nicotine withdrawal syndrome.

  6. Greater expression of Chrna3 is found in whole brain and dissected brain regions relevant to locomotor behavior in mice that are less sensitive to ethanol-induced stimulation compared to mice that are robustly stimulated.

  7. Polymorphisms located within the Chrna5-Chrna3-Chrnb4 cluster on mouse chromosome 9 were found to co-segregate with alcohol preference, with high-drinking F(2) mice carrying B6 alleles and low-drinking F(2) mice carrying D2 alleles.

  8. The results of this study demonstrated that hyperglycemia also interferes with the function of alpha3-containing nAChRs through Cys (show DNAJC5 Proteins) residues on the alpha3 subunit

  9. functional nicotinic ACh (show FGFR3 Proteins) receptors are detected on stem and progenitor cells of fetal mouse cerebral cortex as early as embryonic day 10

  10. Our results suggest that PrP(C (show PRNP Proteins)) is a member of a multiprotein membrane complex participating in the formation and function of alpha3beta4 nAChR (show CHRNA4 Proteins).

Cholinergic Receptor, Nicotinic, alpha 3 (Neuronal) (CHRNA3) Protein Profile

Protein Summary

This locus encodes a member of the nicotinic acetylcholine receptor family of proteins. Members of this family of proteins form pentameric complexes comprised of both alpha and beta subunits. This locus encodes an alpha-type subunit, as it contains characteristic adjacent cysteine residues. The encoded protein is a ligand-gated ion channel that likely plays a role in neurotransmission. Polymorphisms in this gene have been associated with an increased risk of smoking initiation and an increased susceptibility to lung cancer. Alternatively spliced transcript variants have been described.

Alternative names and synonyms associated with Cholinergic Receptor, Nicotinic, alpha 3 (Neuronal) (CHRNA3)

  • cholinergic receptor, nicotinic, alpha 3 (neuronal) (CHRNA3)
  • neuronal acetylcholine receptor subunit alpha-3-like (LOC716571)
  • neuronal acetylcholine receptor subunit alpha-3-like (LOC100390104)
  • cholinergic receptor, nicotinic, alpha 3 (CHRNA3)
  • cholinergic receptor, nicotinic, alpha polypeptide 3 (Chrna3)
  • cholinergic receptor, nicotinic, alpha 3 (neuronal) (Chrna3)
  • (a)3 protein
  • A730007P14Rik protein
  • Acra-3 protein
  • Acra3 protein
  • LNCR2 protein
  • NACHRA3 protein
  • PAOD2 protein

Protein level used designations for CHRNA3

cholinergic receptor, nicotinic, alpha polypeptide 3 , neuronal acetylcholine receptor subunit alpha-3 , neuronal nicotinic acetylcholine receptor, alpha3 subunit , neuronal acetylcholine receptor subunit alpha-3-like , cholinergic receptor, nicotinic, alpha 3 , alpha 3 , neuronal nicotinic acetylcholine receptor, alpha 3 subunit , Acetylcholine receptor alpha 3 (neuronal nicotine) , cetylcholine receptor alpha 3 (neuronal nicotine) , cholinergic receptor nicotinic alpha polypeptide 4 , neuronal nicotinic acetylcholine receptor subunit 3

GENE ID SPECIES
1136 Homo sapiens
716571 Macaca mulatta
100390104 Callithrix jacchus
100456898 Pongo abelii
110834 Mus musculus
100219339 Taeniopygia guttata
25101 Rattus norvegicus
386578 Gallus gallus
282702 Bos taurus
482111 Canis lupus familiaris
100037403 Felis catus
100342666 Oryctolagus cuniculus
100581530 Nomascus leucogenys
100151989 Sus scrofa
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