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CHRNA3 Products

(Cholinergic Receptor, Nicotinic, alpha 3 (Neuronal) (CHRNA3))
This locus encodes a member of the nicotinic acetylcholine receptor family of proteins. Members of this family of proteins form pentameric complexes comprised of both alpha and beta subunits. This locus encodes an alpha-type subunit, as it contains characteristic adjacent cysteine residues. The encoded protein is a ligand-gated ion channel that likely plays a role in neurotransmission. Polymorphisms in this gene have been associated with an increased risk of smoking initiation and an increased susceptibility to lung cancer. Alternatively spliced transcript variants have been described. [provided by RefSeq, Nov 2009].

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Featured CHRNA3 Categories

CHRNA3 Antibodies

High quality antibodies with extensive validation data.

CHRNA3 ELISA Kits

Reliable ELISA kits for a wide range of species.

CHRNA3 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended CHRNA3 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IHC, ICC, FACS, Neut
Validations
  • (1)
  • (7)
Cat. No. ABIN5611357
Quantity 0.1 mg
Datasheet Datasheet
Reactivity Human
Application WB, IHC, ICC, IP
Validations
  • (4)
Cat. No. ABIN7440989
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC (p)
Validations
  • (1)
  • (2)
Cat. No. ABIN651212
Quantity 400 μL
Datasheet Datasheet

Recommended CHRNA3 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6954755
Quantity 96 tests
Datasheet Datasheet

Recommended CHRNA3 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1349400
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1349398
Quantity 10 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN3126794
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our CHRNA3 products

Kulbatskii, Shenkarev, Bychkov, Loktyushov, Shulepko, Koshelev, Povarov, Popov, Peigneur, Chugunov, Kozlov, Sharonova, Efremov, Skrebitsky, Tytgat, Kirpichnikov, Lyukmanova: "Human Three-Finger Protein Lypd6 Is a Negative Modulator of the Cholinergic System in the Brain." in: Frontiers in cell and developmental biology, Vol. 9, pp. 662227, (2021) (PubMed).

Gonzalez-Islas, Garcia-Bereguiain, OFlaherty, Wenner: "Tonic nicotinic transmission enhances spinal GABAergic presynaptic release and the frequency of spontaneous network activity." in: Developmental neurobiology, Vol. 76, Issue 3, pp. 298-312, (2016) (PubMed).

Kim, Choi, Joo, Bae, Ma, Lee, Kim: "Nicotine-Induced Apoptosis in Human Renal Proximal Tubular Epithelial Cells." in: PLoS ONE, Vol. 11, Issue 3, pp. e0152591, (2016) (PubMed).

Pfaender, Föhr, Lutz, Putz, Achberger, Linta, Liebau, Boeckers, Grabrucker: "Cellular Zinc Homeostasis Contributes to Neuronal Differentiation in Human Induced Pluripotent Stem Cells." in: Neural plasticity, Vol. 2016, pp. 3760702, (2016) (PubMed).

Chernyavsky, Shchepotin, Galitovkiy, Grando: "Mechanisms of tumor-promoting activities of nicotine in lung cancer: synergistic effects of cell membrane and mitochondrial nicotinic acetylcholine receptors." in: BMC cancer, Vol. 15, pp. 152, (2015) (PubMed).

Chernyavsky, Galitovskiy, Grando: "Molecular mechanisms of synergy of corneal muscarinic and nicotinic acetylcholine receptors in upregulation of E-cadherin expression." in: International immunopharmacology, Vol. 29, Issue 1, pp. 15-20, (2015) (PubMed).

Paez-Gonzalez, Asrican, Rodriguez, Kuo: "Identification of distinct ChAT⁺ neurons and activity-dependent control of postnatal SVZ neurogenesis." in: Nature neuroscience, Vol. 17, Issue 7, pp. 934-42, (2014) (PubMed).

Synonyms and alternative names related to CHRNA3

cholinergic receptor nicotinic alpha 3 subunit (CHRNA3), cholinergic receptor, nicotinic, alpha polypeptide 3 (Chrna3), cholinergic receptor nicotinic alpha 3 subunit (Chrna3), (a)3, A730007P14Rik, Acra-3, Acra3, LNCR2, NACHRA3, PAOD2

Protein level used designations for CHRNA3

  • cholinergic receptor, nicotinic, alpha polypeptide 3
  • neuronal acetylcholine receptor subunit alpha-3
  • neuronal nicotinic acetylcholine receptor, alpha3 subunit
  • neuronal acetylcholine receptor subunit alpha-3-like
  • cholinergic receptor, nicotinic, alpha 3
  • alpha 3
  • neuronal nicotinic acetylcholine receptor, alpha 3 subunit
  • Acetylcholine receptor alpha 3 (neuronal nicotine)
  • cetylcholine receptor alpha 3 (neuronal nicotine)
  • cholinergic receptor nicotinic alpha polypeptide 4
  • neuronal nicotinic acetylcholine receptor subunit 3
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