Browse our CBP Proteins (CREBBP)

Full name:
CREB Binding Protein Proteins (CREBBP)
On www.antibodies-online.com are 11 CREB Binding Protein (CREBBP) Proteins from 6 different suppliers available. Additionally we are shipping CBP Antibodies (145) and CBP Kits (13) and many more products for this protein. A total of 176 CBP products are currently listed.
Synonyms:
AW558298, CBBM, Cbp, CBP/p300, COD5, crebbp, F730007C19Rik, hmm291030, KAT3A, Nejire, p300/CBP, Pag, RCP, ROP, RSTS, RTS
list all proteins Gene Name GeneID UniProt
CREBBP 1387 Q92793
CREBBP 12914  
CREBBP 54244  

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Human CREB Binding Protein (CREBBP) interaction partners

  1. Data show that specifically inhibiting the interaction between CBP and catenin with ICG-001 results in the differentiation of quiescent drug-resistant chronic myelogenous leukemia-initiating cells (CML LICs).

  2. 5-FU promotes global histone de-acetylation by enhancing the degradation of p300/CBP in colorectal neoplasms.

  3. CREBBP mutations were associated with inferior progression-free survival (PFS), whereas mutations in previously unreported HVCN1 (show HVCN1 Proteins), a voltage-gated proton channel-encoding gene and B-cell receptor signaling modulator, were associated with improved PFS.

  4. the rate-limiting transition state for binding between the TAZ1 (show TAZ Proteins) domain of CREB binding protein and the intrinsically disordered transactivation domain of STAT2 (show STAT2 Proteins) (TAD (show CRTAM Proteins)-STAT2 (show STAT2 Proteins)) by site-directed mutagenesis and kinetic experiments (Phi-value analysis) and found that the native protein-protein binding interface is not formed at the transition state for binding.

  5. In targeted sequencing, a disruptive mutation of TNFAIP3 (show TNFAIP3 Proteins) was the most common alteration (54%), followed by mutations of TBL1XR1 (show TBL1XR1 Proteins) (18%) and cAMP response element binding proteins (CREBBP) (17%).

  6. A mosaic variant in CREBBP identified as pathogenic in a patient with overlapping clinical features of Rubinstein-Taybi and Filippi syndromes tested negative for CKAP2L.

  7. CREBBP-BCORL1 fusion is associated with ossifying fibromyxoid tumors.

  8. Mapping the interactions of adenoviral E1A (show BCKDHA Proteins) proteins with the p160 (show MSH6 Proteins) nuclear receptor coactivator binding domain of CBP

  9. CREBBP mutations might assist in enhancing oncogenic RAS signaling in acute lymphoblastic leukemia but do not alter response to MEK (show MAP2K1 Proteins) inhibitors.

  10. Mutations identified in patients with and without classical Rubinstein-Taybi syndrome lead to skipping of exon20 of CREBBP.

Mouse (Murine) CREB Binding Protein (CREBBP) interaction partners

  1. High CBP-P300 expression is associated with lymphoma.

  2. This study provides evidence from transgenic mouse models that Crebbp deletion results in deficits in B-cell development and can cooperate with Bcl2 (show BCL2 Proteins) overexpression to promote B-cell lymphoma.

  3. Data (including data from studies of hydrogen-deuterium exchange coupled to mass spectrometry in presence of denaturants) suggest that, for peptide fragments of human ACTR (show NCOA3 Proteins) and mouse Crebbp representing disordered interaction domains, exchange rates are changed dramatically by high concentrations of denaturants guanidinium chloride or urea. (ACTR (show NCOA3 Proteins) = activator of thyroid and retinoid receptor; Crebbp = CREB binding protein)

  4. Crebbp+/- common myeloid progenitors and granulocyte/macrophage progenitors could trigger skewed myelopoiesis, myelodysplasia and late-onset acute myeloid leukemia (show BCL11A Proteins).

  5. Brd3 (show BRD3 Proteins) knockout significantly decreased the recruitment of acetylase CBP to IL6 (show IL6 Proteins) gene promoter, and the acetylation level of histone3 within IL6 (show IL6 Proteins) gene promoter was repressed.

  6. Inhibition of hypothalamic Cbp results in profound obesity and impaired glucose homeostasis, increased food intake, and decreased body temperature. In addition, these changes are accompanied by molecular evidence in the hypothalamus for impaired leptin (show LEP Proteins) and insulin (show INS Proteins) signaling, a shift from glucose to lipid metabolism, and decreased Pomc (show POMC Proteins) mRNA, with no effect on locomotion.

  7. our findings illustrate that Cbp is an important regulator of Csk (show CSK Proteins) recruitment to the SFK Lyn (show LYN Proteins) in Eporesponsive erythroid cells.

  8. Study demonstrates that CBP binds directly to RNAs in vivo and in vitro. RNAs bound to CBP in vivo include a large number of eRNAs. Using steady-state histone acetyltransferase (HAT) assays, study shows that an RNA binding region in the HAT domain of CBP-a regulatory motif unique to CBP/p300-allows RNA to stimulate CBP's HAT activity.

  9. We focused on genomic loci bound by the neuronal activity-regulated coactivator CREBBP, and we measured enhancer and promoter activities both before and after neuronal activation

  10. Cyclic AMP Response Element Binding Protein Mediates Pathological Retinal Neovascularization via Modulating DLL4 (show DLL4 Proteins)-NOTCH1 (show NOTCH1 Proteins) Signaling

CBP (CREBBP) Protein Profile

Protein Summary

This gene encodes for a light absorbing visual pigment of the opsin gene family. The encoded protein is called red cone photopigment or long-wavelength sensitive opsin. Opsins are G-protein coupled receptors with seven transmembrane domains, an N-terminal extracellular domain, and a C-terminal cytoplasmic domain. This gene and the medium-wavelength opsin gene are tandemly arrayed on the X chromosome and frequent unequal recombination and gene conversion may occur between these sequences. X chromosomes may have fusions of the medium- and long-wavelength opsin genes or may have more than one copy of these genes. Defects in this gene are the cause of partial, protanopic colorblindness.

Alternative names and synonyms associated with CBP (CREBBP)

  • CREB binding protein (CREBBP)
  • CREB binding protein (crebbp-b)
  • CREB binding protein (Crebbp)
  • opsin 1 (cone pigments), long-wave-sensitive (OPN1LW)
  • phosphoprotein associated with glycosphingolipid microdomains 1 (Pag1)
  • AW558298 protein
  • CBBM protein
  • Cbp protein
  • CBP/p300 protein
  • COD5 protein
  • crebbp protein
  • F730007C19Rik protein
  • hmm291030 protein
  • KAT3A protein
  • Nejire protein
  • p300/CBP protein
  • Pag protein
  • RCP protein
  • ROP protein
  • RSTS protein
  • RTS protein

Protein level used designations for CREB Binding Protein Proteins (CREBBP)

CREB binding protein (Rubinstein-Taybi syndrome) , CREB-binding protein , cone dystrophy 5 (X-linked) , long-wave-sensitive opsin 1 , red cone photoreceptor pigment , red-sensitive opsin , Csk-binding protein , phosphoprotein associated with glycosphingolipid-enriched microdomains 1 , phosphoprotein transmembrane adaptor 1 , phosphoprotein-associated with GEMs , transmembrane phosphoprotein Cbp

GENE ID SPECIES
467891 Pan troglodytes
495689 Xenopus laevis
704331 Macaca mulatta
100123220 Nasonia vitripennis
1387 Homo sapiens
12914 Mus musculus
54244 Rattus norvegicus
505453 Bos taurus
479866 Canis lupus familiaris
5956 Homo sapiens
94212 Mus musculus
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