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|Antigen||Tumor Necrosis Factor Receptor Superfamily, Member 9 (TNFRSF9) Antibodies|
|Epitope||AA 115-165 Alternatives|
|Reactivity||Human, Mouse (Murine), Rat (Rattus) Alternatives|
|Conjugate||This CD137 antibody is un-conjugated Alternatives|
Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
|2 references available|
|Supplier||Log in to see|
Product Details anti-CD137 AntibodyTarget Details CD137 Application Details Handling References for anti-CD137 antibody (ABIN740445) Images
|Purification||Purified by Protein A.|
|Immunogen||KLH conjugated synthetic peptide derived from human CD137|
Target Details CD137Product Details anti-CD137 Antibody Application Details Handling References for anti-CD137 antibody (ABIN740445) Images back to top
|Alternative Name||CD137 (TNFRSF9 Antibody Abstract)|
Receptor for TNFSF9/4-1BBL. Possibly active during T cell activation.
Subcellular location: Membrane bound, Cell membrane
Synonyms: ILA, 4-1BB, CD137, CDw137, Tumor necrosis factor receptor superfamily member 9, 4-1BB ligand receptor, T-cell antigen 4-1BB homolog, T-cell antigen ILA, TNFRSF9
|Research Area||Stem Cells, Hematopoietic Progenitors, Cytokines, Innate Immunity, CD Antigens, Apoptosis/Necrosis, Surface Receptors of Immune Cells|
Application DetailsProduct Details anti-CD137 Antibody Target Details CD137 Handling References for anti-CD137 antibody (ABIN740445) Images back to top
|Restrictions||For Research Use only|
HandlingProduct Details anti-CD137 Antibody Target Details CD137 Application Details References for anti-CD137 antibody (ABIN740445) Images back to top
|Buffer||Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.|
|Precaution of Use||This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.|
|Storage Comment||Store at -20°C|
|Expiry Date||12 months|
References for anti-CD137 antibody (ABIN740445)Product Details anti-CD137 Antibody Target Details CD137 Application Details Handling Images back to top
|Product cited in:||
Claycombe, Vomhof-DeKrey, Garcia, Johnson, Uthus, Roemmich et al.: "Decreased beige adipocyte number and mitochondrial respiration coincide with increased histone methyl transferase (G9a) and reduced FGF21 gene expression in Sprague-Dawley rats fed prenatal low ..." in: The Journal of nutritional biochemistry, Vol. 31, pp. 113-21, 2016 Method employed by authors: Flow Cytometry (FACS) (Sample species: Rat (Rattus)).
Daquinag, Tseng, Salameh, Zhang, Amaya-Manzanares, Dadbin, Florez, Xu, Tong, Kolonin: "Depletion of white adipocyte progenitors induces beige adipocyte differentiation and suppresses obesity development." in: Cell death and differentiation, 2014
ImagesProduct Details anti-CD137 Antibody Target Details CD137 Application Details Handling References for anti-CD137 antibody (ABIN740445) back to top
|Method validated||Flow Cytometry|
|Positive Control||rat adipose-derived mesenchymal stem cells|
|Negative Control||cells stained with secondary antibody only|
Passed. ABIN740445 specifically recognizes Cd137 in rat adipose-derived mesenchymal stem cells.
|Secondary Antibody||donkey anti-rabbit Alexa Fluor 680 conjugated antibody (ThermoFisher Scientific, A10043, lot 1812322)|
ABIN740445 reveals a specific fluorescence signal in rat adipose-derived mesenchymal stem cells. This is the first time that flow cytometry is performed in this type of cells using this antibody. No signal was registered in the negative control cells.