You are viewing an incomplete version of our website. Please click to reload the website as full version.

anti-Rhesus Monkey CD28 antibody for Flow Cytometry

Recommended CD28 Antibody (supplied by: Log in to see )

Antigen
CD28 Antibodies
  • CD28RNA
  • Tp44
Reactivity
Baboon, Cynomolgus, Rhesus Monkey
442
363
106
69
44
31
26
23
23
23
12
6
2
1
Host
Mouse
511
203
77
66
25
23
7
Clonality
Monoclonal
Conjugate
This CD28 antibody is un-conjugated
115
96
75
41
17
17
15
13
12
12
11
10
9
9
9
9
9
9
9
8
8
8
6
5
4
4
3
2
2
2
2
2
2
2
2
2
1
1
1
Application
Flow Cytometry (FACS)
733
265
178
132
122
118
116
111
86
66
22
13
4
3
3
3
3
3
2
2
1
1
1
1
Supplier
Log in to see
Supplier Product No.
Log in to see
Request

Get this product for free

It's quick and easy to submit your validation proposal. I want to validate this product

Learn more

Catalog No. ABIN2689147
Contact our Customer Service for availability and price in your country.

Similar anti-CD28 Antibodies

Application / Reactivity Baboon Cynomolgus Rhesus Monkey
Flow Cytometry (FACS) 1 Antibodies 1 Antibodies 1 Antibodies

General

Antigen CD28 Antibodies
Reactivity Baboon, Cynomolgus, Rhesus Monkey
(442), (363), (106), (69), (44), (31), (26), (23), (23), (23), (12), (6), (2), (1)
Host Mouse
(511), (203), (77), (66), (25), (23), (7)
Clonality (Clone)
Monoclonal   ( )
Conjugate This CD28 antibody is un-conjugated
(115), (96), (75), (41), (17), (17), (15), (13), (12), (12), (11), (10), (9), (9), (9), (9), (9), (9), (9), (8), (8), (8), (6), (5), (4), (4), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1)
Application Flow Cytometry (FACS)
(733), (265), (178), (132), (122), (118), (116), (111), (86), (66), (22), (13), (4), (3), (3), (3), (3), (3), (2), (2), (1), (1), (1), (1)
Supplier Log in to see

Product Details anti-CD28 Antibody

Target Details CD28 Application Details Handling Images
Brand BD Pharmingen™
Characteristics The CD28.2 monoclonal antibody specifically binds to CD28, a 44 kDa homodimeric transmembrane glycoprotein present on most mature T cells, thymocytes and plasma cells. CD28 is a costimulatory receptor that binds CD80 and CD86 as ligands and plays a very important role in T cell-B cell interactions. It has been suggested that CD28 initiates and regulates a separate and distinct signal transduction pathway from those stimulated by the TCR complex. Additionally, it has been reported that CD28 antibody clones vary in their ability to stimulate T cells to produce IL-2 and increase intracellular Ca2+ concentration. This finding suggests the existence of functionally distinct subregions on the CD28 Molecule. CD28.2 has been demonstrated to bind to the same molecule as clone L293, another CD28 mAb, and has been reported to induce Ca2+ influx in Jurkat T cells. This clone also cross-reacts with a subset of peripheral blood lymphocytes, but not monocytes or granulocytes, of baboon, rhesus and cynomolgus macaques. The distribution on lymphocytes is similar to that observed with normal human donor lymphocytes, however, as described in the literature, the frequency of CD28.2-positive lymphocytes is reduced in the non-human primate, with the majority of cells being CD28 negative. Profile of anti-CD28 reactivity on peripheral blood lymphocytes of Rhesus macaque (macaca mulatta) analyzed by flow cytometry.

BD Pharmingen™ Purified Mouse Anti-Human CD28 - Purified - Clone CD28.2 - Isotype Mouse IgG1, κ - Reactivity Bab, Cyno, Rhe - 0.1 mg
Purification The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
Immunogen Human CD28 Transfected Cell Line
Clone CD28-2
Isotype IgG1, kappa

Target Details CD28

Product Details anti-CD28 Antibody Application Details Handling Images back to top
Antigen
Alternative Name CD28 (CD28 Antibody Abstract)
Background Synonyms: CD28 antigen, T44, Tp44, TP44
Research Area Immunology, Adaptive Immunity, Hematopoietic Progenitors, CD Antigens, Surface Receptors of Immune Cells, Apoptosis/Necrosis
Pathways TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway

Application Details

Product Details anti-CD28 Antibody Target Details CD28 Handling Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-CD28 Antibody Target Details CD28 Application Details Images back to top
Concentration 0.5 mg/mL
Buffer Aqueous buffered solution containing ≤0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C
Storage Comment Store undiluted at 4°C.