You are viewing an incomplete version of our website. Please click to reload the website as full version.

anti-Bird (Avian) CD8 antibody for Flow Cytometry

Recommended CD8 Antibody (supplied by: Log in to see )

Antigen
CD8a Molecule (CD8A) Antibodies
  • BB154331
  • CD8
  • cd8
  • Leu2
  • LOC100136450
  • Ly-2
  • Ly-35
  • Ly-B
  • Lyt-2
  • MAL
  • p32
  • RHACD8-4
  • zgc:136643
Reactivity
Bird (Avian)
1059
532
167
68
47
40
25
22
20
20
19
16
15
13
12
12
11
11
10
10
8
8
5
3
3
2
2
2
2
1
1
1
Host
Mouse
1286
512
206
Clonality
Monoclonal
Conjugate
This CD8 antibody is un-conjugated
259
217
142
86
52
42
40
39
30
30
29
28
27
26
25
25
25
25
25
21
21
18
18
17
11
10
10
10
8
6
6
5
4
4
4
3
3
3
3
3
3
3
3
3
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Flow Cytometry (FACS), Immunoprecipitation (IP)
1618
452
356
343
285
282
255
238
214
37
33
25
23
17
14
10
7
6
6
6
5
4
4
4
3
2
2
2
2
2
2
1
1
1
1
1
1
1
1
Supplier
Log in to see
Supplier Product No.
Log in to see
Request

Get this product for free

It's quick and easy to submit your validation proposal. I want to validate this product

Learn more

Catalog No. ABIN255415
Contact our Customer Service for availability and price in your country.

Similar anti-CD8 Antibodies

Application / Reactivity Bird (Avian)
Flow Cytometry (FACS) 1 Antibodies
Immunoprecipitation (IP) 1 Antibodies

General

Antigen CD8a Molecule (CD8A) Antibodies
Reactivity Bird (Avian)
(1059), (532), (167), (68), (47), (40), (25), (22), (20), (20), (19), (16), (15), (13), (12), (12), (11), (11), (10), (10), (8), (8), (5), (3), (3), (2), (2), (2), (2), (1), (1), (1)
Host Mouse
(1286), (512), (206)
Clonality (Clone)
Monoclonal   ( )
Conjugate This CD8 antibody is un-conjugated
(259), (217), (142), (86), (52), (42), (40), (39), (30), (30), (29), (28), (27), (26), (25), (25), (25), (25), (25), (21), (21), (18), (18), (17), (11), (10), (10), (10), (8), (6), (6), (5), (4), (4), (4), (3), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Flow Cytometry (FACS), Immunoprecipitation (IP)
(1618), (452), (356), (343), (285), (282), (255), (238), (214), (37), (33), (25), (23), (17), (14), (10), (7), (6), (6), (6), (5), (4), (4), (4), (3), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Supplier Log in to see

Product Details anti-CD8 Antibody

Target Details CD8 Application Details Handling Images
Specificity NB100-64369 recognizes Pekin duck CD8 alpha (CD8a), shown to be expressed by thymocytes, splenocytes, peripheral lymphoid cells and the vast majority of bursal cells. Since the majority of avian immune studies have been carried out on chickens, relatively little is known about the immune system of ducks, though there is a resemblance between the main lymphoid organs: the spleen, thymus and bursa of Fabricius. At the cellular level, studies have shown that like mammalian T cells, duck lymphocytes are responsive to phytohaemagglutinin (PHA). Double-staining with clone Du CD8-1 and duck IgY light chain clone 14A3, revealed the presence of a CD8^high /14A3^- cytotoxic T cell population and a CD8^low/14A3^+ B cell population in duck spleen and also revealed a high percentage of CD8^+/14A3^+ cells in duck bursa ^(1).
No Cross-Reactivity Chicken
Purification Protein G purified
Immunogen 293T cells expressing Pekin Duck CD8 alpha.
Clone Du CD8-1
Isotype IgG2b

Target Details CD8

Product Details anti-CD8 Antibody Application Details Handling Images back to top
Antigen
Alternative Name CD8 (CD8A Antibody Abstract)
Background The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytesthat mediates efficient cell to cell interactions within the immune system. The CD8antigen, acting as a coreceptor, and the T cell receptor on the T lymphocyte recognizeantigen displayed by an antigen presenting cell (APC) in the context of class I MHCmolecules. The functional coreceptor is either a homodimer composed of two alphachains, or a heterodimer composed of one alpha and one beta chain. Both alpha andbeta chains share significant homology to immunoglobulin variable light chains. Alternate Names: anti-CD 8a antibody, anti-CD8 alpha chain antibody, anti-CD8 antibody, anti-CD8antigen alpha chain antibody, anti-CD8 antigen alpha polypeptide (p32) antibody,anti-CD8a antibody, anti-CD8a antigen antibody, anti-CD8a molecule antibody, anti-Leu2 antibody, anti-Leu2 antibody, anti-Leu2 T lymphocyte antigen antibody, anti-MALantibody, anti-OKT8 T cell antigen antibody, anti-p32 antibody, anti-T cell antigen Leu2antibody, anti-T cell co receptor antibody, anti-T cell coreceptor antibody, anti-T cellsurface glycoprotein CD8 alpha chain antibody, anti-T lymphocyte differentiation antigenT8/Leu 2 antibody, anti-T lymphocyte differentiation antigen T8/Leu2 antibody, anti-T8 Tcell antigen antibody.
Gene Symbol: CD8A
Gene ID 925
Research Area Immunology, Adaptive Immunity, Hematopoietic Progenitors, CD Antigens, Surface Receptors of Immune Cells
Pathways TCR Signaling

Application Details

Product Details anti-CD8 Antibody Target Details CD8 Handling Images back to top
Application Notes Recommended dilutions: Flow Cytometry 1:10-1:1000, Immunoprecipitation 1:10-1:500
Restrictions For Research Use only

Handling

Product Details anti-CD8 Antibody Target Details CD8 Application Details Images back to top
Concentration 1.0 mg/mL
Buffer PBS, Sodium Azide
Preservative Sodium azide
Precaution of Use WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
Handling Advice Avoid freeze-thaw cycles
Storage 4 °C
Storage Comment 4 °C short term. Aliquot and store at -20 °C long term.