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|Antigen||CD8a Molecule (CD8A) Antibodies|
|Reactivity||Guinea Pig Alternatives|
|Conjugate||This CD8 antibody is un-conjugated Alternatives|
Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))
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Product Details anti-CD8 AntibodyTarget Details CD8 Application Details Handling Images
|Specificity||This antibody reacts with an antigen present on a subset of T-lymphocytes with the same distribution as CD8 positive T-cells in man and Mouse.|
|Characteristics||Synonyms: T-lymphocyte differentiation antigen T8/Leu-2, T-cell surface glycoprotein CD8 alpha chain|
|Immunogen||Peritoneal T-cells. lymph node cells from immunised BALB/c mice were fused with cells ofthe SP2/0 mouse myeloma cell line.|
Target Details CD8Product Details anti-CD8 Antibody Application Details Handling Images back to top
|Alternative Name||CD8 (CD8A Antibody Abstract)|
|Background||The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell to cell interactions within the immune system. The CD8 antigen, acting as a coreceptor, and the T cell receptor on the T lymphocyte recognize antigen displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains.Synonyms: CD8 alpha chain, CD8A, MAL, T-cell surface glycoprotein CD8 alpha chain, T-lymphocyte differentiation antigen T8/Leu-2|
|Research Area||Immunology, Adaptive Immunity, Hematopoietic Progenitors, CD Antigens, Surface Receptors of Immune Cells|
Application DetailsProduct Details anti-CD8 Antibody Target Details CD8 Handling Images back to top
Immunohistochemistry on frozen sections: 1/100. Flow Cytometry: 1/100, use 10 μL of the suggested working dilution to label 10^6lymphocytes in 100 μL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
|Restrictions||For Research Use only|
HandlingProduct Details anti-CD8 Antibody Target Details CD8 Application Details Images back to top
|Storage||4 °C/-20 °C|
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
|Expiry Date||12 months|