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anti-Rat (Rattus) Crk antibody for Immunohistochemistry (Paraffin-embedded Sections)

Recommended Crk Antibody (supplied by: Log in to see )

Antigen
V-Crk Sarcoma Virus CT10 Oncogene Homolog (Avian) (CRK) Antibodies
  • c-Crk
  • CG1587
  • crk
  • CRK
  • Crk-I
  • Crk-II
  • Crk-III
  • crk2
  • Crk3
  • crkII
  • CRKII
  • CrkIII
  • Crko
  • D-CRK
  • D-Crk
  • dCrk
  • Dcrk
  • dCRK
  • DCrk
  • Dmel\\CG1587
  • fb34h10
  • fc05a01
  • fi19g05
  • p38
  • P38C-CRK
  • v-crk
  • wu:fb34h10
  • wu:fc05a01
  • wu:fc54a04
  • wu:fi19g05
  • zgc:100936
Epitope
pTyr221
22
16
12
6
5
4
3
3
3
2
2
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
126
59
54
3
2
2
2
2
2
1
Host
Rabbit
95
31
Clonality
Polyclonal
Conjugate
This Crk antibody is un-conjugated
4
4
4
2
2
2
2
2
2
2
2
2
2
2
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
76
43
23
22
22
22
15
14
10
4
4
2
2
Supplier
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Supplier Product No.
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Catalog No. ABIN498832
$ 390.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.34262326 ABIN498920 IHC (p) Rabbit Log in to see Polyclonal
0.00089654163 ABIN265373 EIA IF IHC (p) WB Rabbit Log in to see Polyclonal
0.00089654163 ABIN3042758 IHC (p) WB Rabbit IgG AA 2-246 Log in to see Polyclonal
0.00089654163 ABIN684433 IF (p) IHC (p) WB Rabbit IgG Isoform 2, pTyr221 Log in to see Polyclonal
0.00089654163 ABIN684435 IHC (p) WB Biotin Rabbit IgG Isoform 2, pTyr221 Log in to see Polyclonal
0.00089654163 ABIN684442 IHC (p) WB HRP Rabbit IgG Isoform 2, pTyr221 Log in to see Polyclonal
0.00089654163 ABIN680347 IHC (p) WB HRP Rabbit IgG Log in to see Polyclonal
0.00089654163 ABIN680340 IHC (p) WB Biotin Rabbit IgG Log in to see Polyclonal
0.00089654163 ABIN680338 IF (p) IHC (p) WB Rabbit IgG Log in to see Polyclonal
0.00089654163 ABIN757267 IF (p) IHC (p) WB Rabbit IgG pSer41 Log in to see Polyclonal
0.00089654163 ABIN3029483 IHC (p) WB Rabbit IgG AA 2-246 Log in to see Polyclonal

Similar anti-Crk Antibodies

Application / Reactivity Human Mouse (Murine) Rat (Rattus)
Western Blotting (WB) 78 Antibodies 35 Antibodies 30 Antibodies
Proximity Ligation Assay (PLA) 2 Antibodies
Immunoprecipitation (IP) 5 Antibodies 4 Antibodies 4 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 15 Antibodies 12 Antibodies 12 Antibodies
Immunohistochemistry (IHC) 22 Antibodies 10 Antibodies 10 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 22 Antibodies 22 Antibodies 22 Antibodies
Immunofluorescence (IF) 25 Antibodies 13 Antibodies 12 Antibodies
Immunocytochemistry (ICC) 17 Antibodies

General

Antigen V-Crk Sarcoma Virus CT10 Oncogene Homolog (Avian) (CRK) Antibodies
Epitope pTyr221
(22), (16), (12), (6), (5), (4), (3), (3), (3), (2), (2), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine), Rat (Rattus)
(126), (59), (54), (3), (2), (2), (2), (2), (2), (1)
Host Rabbit
(95), (31)
Clonality
Polyclonal
Conjugate This Crk antibody is un-conjugated
(4), (4), (4), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1)
Application Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
(76), (43), (23), (22), (22), (22), (15), (14), (10), (4), (4), (2), (2)
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Product Details anti-Crk Antibody

Target Details Crk Application Details Handling Images
Specificity This antibody detects endogenous levels of p-Crk2 protein only when phosphorylated at Try221.
Cross-Reactivity (Details) Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.
Purification Affinity chromatography
Purity > 95 % by SDS-PAGE

Target Details Crk

Product Details anti-Crk Antibody Application Details Handling Images back to top
Antigen
Alternative Name CRK (CRK Antibody Abstract)
Background The Crk family of adapter proteins including Crk II, Crk I and Crk L consist mostly of SH2 and SH3 domains. Through the interactions between SH2 domain and phosphotyrosine residues and/or between SH3 domain and proline- rich motifs, they are involved in a variety of signaling cascades. Crk I and Crk II are encoded by the same gene, which undergoes alternative splicing to yield these two proteins, but differ in their biological activities. Crk II has less transforming activity than Crk I, although both Crk I and Crk II bind to many tyrosine-phosphorylated proteins that bind to GRB2. In addition, Crk II becomes rapidly tyrosine-phosphorylated in response to stimulation with insulin-like growth factor-I (IGFI) and might be involved in the IGF-I receptor signalling pathway. The gene encoding Crk I and II maps to human chromosome 17p13, a region which demonstrates frequent deletion or loss of heterozygosity in a wide range of human cancers.Synonyms: Adapter molecule crk, Proto-oncogene C-crk, p38
Molecular Weight approx. 42 kDa
Gene ID 1398
NCBI Accession NP_005197
UniProt P46108
Pathways TCR Signaling, Neurotrophin Signaling Pathway

Application Details

Product Details anti-Crk Antibody Target Details Crk Handling Images back to top
Application Notes Immunohistochemistry: 1/50 - 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-Crk Antibody Target Details Crk Application Details Images back to top
Concentration 1,0 mg/mL
Buffer Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Images

Product Details anti-Crk Antibody Target Details Crk Application Details Handling back to top
Supplier Images
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Crk antibody (V-Crk Sarcoma Virus CT10 Oncogene Homolog (Avian)) (pTyr221) (ABIN498832) Immunohistochemistry (IHC) analyzes of p-Crk2 antibody in paraffin-embedded hu...