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anti-Human IL17A antibody for Enzyme Immunoassay

Recommended IL17A Antibody (supplied by: Log in to see )

Antigen
Interleukin 17A (IL17A) Antibodies
  • ChIL-17
  • Ctla-8
  • CTLA-8
  • CTLA8
  • Ctla8
  • IL-17
  • IL-17A
  • IL-17F
  • IL17
  • Il17
  • IL17A
Epitope
AA 60-87, Middle Region
30
17
15
15
14
13
13
11
8
7
6
6
4
4
4
3
2
2
1
1
1
1
1
1
Reactivity
Human
430
194
72
10
5
5
1
Host
Rabbit
248
206
111
44
8
3
1
Clonality
Polyclonal
Conjugate
This IL17A antibody is un-conjugated
71
34
34
24
17
16
14
11
8
7
7
7
7
7
7
7
7
7
6
6
5
5
4
3
3
3
2
2
2
2
2
2
2
2
2
1
1
Application
Enzyme Immunoassay (EIA), Western Blotting (WB)
344
312
193
59
43
42
24
22
19
14
11
10
9
9
9
8
7
6
5
4
4
3
2
2
2
2
2
1
1
1
1
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Catalog No. ABIN952921
$ 390.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.0008859144 ABIN499980 EIA WB Rabbit IgG Center Log in to see Polyclonal 1
0.0008859144 ABIN499978 EIA WB Rabbit IgG N-Term Log in to see Polyclonal 1
0.0008859144 ABIN401101 EIA Neut WB Rabbit IgG Log in to see Polyclonal 3
0.0008859144 ABIN401100 EIA Neut WB Rabbit IgG Log in to see Polyclonal 3
0.0008859144 ABIN116118 EIA WB Biotin Rabbit Log in to see Polyclonal
0.0008859144 ABIN116117 EIA WB Biotin Rabbit Log in to see Polyclonal
0.0008859144 ABIN116120 EIA Func IHC (p) WB Rabbit Log in to see Polyclonal
0.0008859144 ABIN116119 EIA Func IHC (p) WB Rabbit Log in to see Polyclonal
0.0008859144 ABIN181572 EIA IHC (p) Neut WB Goat Log in to see Polyclonal
0.0008859144 ABIN181569 EIA WB Biotin Goat Log in to see Polyclonal

Top referenced anti-IL17A antibody for Enzyme Immunoassay

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Application / Reactivity Human
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Blocking Reagent (BR) 2 Antibodies
Confocal Microscopy (CM) 2 Antibodies
Depletion (Dep) 1 Antibodies
ELISA 193 Antibodies
ELISA (Capture) 7 Antibodies
ELISA (Detection) 8 Antibodies
ELISpot 9 Antibodies
ELISpot (Capture) (ELISPOT (Capture)) 3 Antibodies
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Flow Cytometry (FACS) 118 Antibodies
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General

Antigen Interleukin 17A (IL17A) Antibodies
Epitope AA 60-87, Middle Region
(30), (17), (15), (15), (14), (13), (13), (11), (8), (7), (6), (6), (4), (4), (4), (3), (2), (2), (1), (1), (1), (1), (1), (1)
Reactivity Human
(430), (194), (72), (10), (5), (5), (1)
Host Rabbit
(248), (206), (111), (44), (8), (3), (1)
Clonality
Polyclonal
Conjugate This IL17A antibody is un-conjugated
(71), (34), (34), (24), (17), (16), (14), (11), (8), (7), (7), (7), (7), (7), (7), (7), (7), (7), (6), (6), (5), (5), (4), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1)
Application Enzyme Immunoassay (EIA), Western Blotting (WB)
(344), (312), (193), (59), (43), (42), (24), (22), (19), (14), (11), (10), (9), (9), (9), (8), (7), (6), (5), (4), (4), (3), (2), (2), (2), (2), (2), (1), (1), (1), (1)
Pubmed 4 references available
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Product Details anti-IL17A Antibody

Target Details IL17A Application Details Handling References for anti-IL17A Antibody (ABIN952921) Images
Specificity This antibody recognizes Interleukin-17A (IL17A).
Cross-Reactivity (Details) Species reactivity (tested):Human
Purification Purified through a Protein A column followed by peptide affinity purification
Immunogen Synthetic peptide - KLH conjugated - corresponding to the central region (between 60-87aa) of human Interleukin-17A (IL17A).
Isotype Ig

Target Details IL17A

Product Details anti-IL17A Antibody Application Details Handling References for anti-IL17A Antibody (ABIN952921) Images back to top
Antigen
Alternative Name Interleukin-17A (IL17A) (IL17A Antibody Abstract)
Background The protein encoded by the IL17A gene is a proinflammatory cytokine produced by activated T cells. This cytokine regulates the activities of NF-kappaB and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO). High levels of this cytokine are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis.Synonyms: CTLA-8, CTLA8, Cytotoxic T-lymphocyte-associated antigen 8, IL-17, IL-17A, IL17
Gene ID 3605
NCBI Accession NP_002181
Research Area Cytokines, Receptors, Inflammation, Immunology, Virology, Cancer
Pathways TCR Signaling

Application Details

Product Details anti-IL17A Antibody Target Details IL17A Handling References for anti-IL17A Antibody (ABIN952921) Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-IL17A Antibody Target Details IL17A Application Details References for anti-IL17A Antibody (ABIN952921) Images back to top
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS with 0.09 % (W/V) Sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

References for anti-IL17A Antibody (ABIN952921)

Product Details anti-IL17A Antibody Target Details IL17A Application Details Handling Images back to top
Background publications

Chen, Xie, Cheng, Diao, Cheng, Liu, Xie, Chen, Zhu: "Role of interleukin-17 in lymphangiogenesis in non-small-cell lung cancer: Enhanced production of vascular endothelial growth factor C in non-small-cell lung carcinoma cells." in: Cancer science, Vol. 101, Issue 11, pp. 2384-90, 2010

Dart, Jankowska-Gan, Huang, Roenneburg, Keller, Torrealba, Rhoads, Kim, Bobadilla, Haynes, Wilkes, Burlingham, Greenspan: "Interleukin-17-dependent autoimmunity to collagen type V in atherosclerosis." in: Circulation research, Vol. 107, Issue 9, pp. 1106-16, 2010

Marwaha, Crome, Panagiotopoulos, Berg, Qin, Ouyang, Xu, Priatel, Levings, Tan: "Cutting edge: Increased IL-17-secreting T cells in children with new-onset type 1 diabetes." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 185, Issue 7, pp. 3814-8, 2010

Crome, Clive, Wang, Kang, Chow, Yu, Lai, Ghahary, Broady, Levings: "Inflammatory effects of ex vivo human Th17 cells are suppressed by regulatory T cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 185, Issue 6, pp. 3199-208, 2010

Images

Product Details anti-IL17A Antibody Target Details IL17A Application Details Handling References for anti-IL17A Antibody (ABIN952921) back to top
Supplier Images
Western Blotting (WB) image for anti-IL17A antibody (Interleukin 17A) (AA 60-87) (ABIN952921) Western blot analysis of IL17A (arrow) using Interleukin-17A (IL17A) Antibody ; 293 c...