anti-Human IL17A antibody for Enzyme Immunoassay

Recommended IL17A Antibody (supplied by: Log in to see )

Antigen
Interleukin 17A (IL17A) Antibodies
  • Il17
  • IL17A
  • CTLA8
  • IL-17
  • IL-17A
  • IL17
  • Ctla-8
  • Ctla8
  • CTLA-8
  • ChIL-17
  • IL-17F
  • interleukin 17A
  • interleukin 17A-like
  • interleukin 17F
  • Il17a
  • IL17A
  • LOC100339322
  • IL17F
Epitope
AA 60-87, Middle Region
27
24
12
12
11
10
9
7
7
6
4
4
3
3
2
2
1
1
1
1
1
Reactivity
Human
373
133
41
7
7
5
3
3
2
2
Host
Rabbit
248
133
77
40
3
3
Clonality
Polyclonal
Conjugate
This IL17A antibody is un-conjugated
56
32
27
20
16
15
15
12
11
11
10
7
7
7
7
7
5
5
5
4
4
4
4
4
4
3
2
2
1
Application
Enzyme Immunoassay (EIA), Western Blotting (WB)
269
229
195
44
30
20
19
15
8
8
8
7
7
6
6
4
4
4
3
3
2
1
1
1
1
1
1
1
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Catalog No. ABIN952921
$ 390.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN5551704 EIA Neut WB Rabbit IgG Log in to see Polyclonal
1 ABIN5554866 EIA WB Rabbit IgG N-Term Log in to see Polyclonal
1 ABIN5554867 EIA WB Rabbit IgG Center Log in to see Polyclonal
1 ABIN116118 EIA WB Biotin Rabbit Log in to see Polyclonal
1 ABIN116117 EIA WB Biotin Rabbit Log in to see Polyclonal
1 ABIN116119 EIA Func IHC (p) WB Rabbit Log in to see Polyclonal
1 ABIN116120 EIA Func IHC (p) WB Rabbit Log in to see Polyclonal
1 ABIN181572 EIA IHC (p) Neut WB Goat Log in to see Polyclonal
1 ABIN181569 EIA WB Biotin Goat Log in to see Polyclonal
1 ABIN5565703 EIA RIA Biotin Rabbit AA 24-155 Log in to see Polyclonal
1 ABIN5565701 EIA RIA Rabbit AA 24-155 Log in to see Polyclonal

General

Antigen Interleukin 17A (IL17A) Antibodies
Epitope AA 60-87, Middle Region
(27), (24), (12), (12), (11), (10), (9), (7), (7), (6), (4), (4), (3), (3), (2), (2), (1), (1), (1), (1), (1)
Reactivity Human
(373), (133), (41), (7), (7), (5), (3), (3), (2), (2)
Host Rabbit
(248), (133), (77), (40), (3), (3)
Clonality
Polyclonal
Conjugate This IL17A antibody is un-conjugated
(56), (32), (27), (20), (16), (15), (15), (12), (11), (11), (10), (7), (7), (7), (7), (7), (5), (5), (5), (4), (4), (4), (4), (4), (4), (3), (2), (2), (1)
Application Enzyme Immunoassay (EIA), Western Blotting (WB)
(269), (229), (195), (44), (30), (20), (19), (15), (8), (8), (8), (7), (7), (6), (6), (4), (4), (4), (3), (3), (2), (1), (1), (1), (1), (1), (1), (1)
Pubmed 4 references available
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Product Details anti-IL17A Antibody

Target Details IL17A Application Details Handling ProductDetails: References for anti-IL17A antibody (ABIN952921) Images
Specificity This antibody recognizes Interleukin-17A (IL17A).
Cross-Reactivity (Details) Species reactivity (tested):Human
Purification Purified through a Protein A column followed by peptide affinity purification
Immunogen Synthetic peptide - KLH conjugated - corresponding to the central region (between 60-87aa) of human Interleukin-17A (IL17A).
Isotype Ig

Target Details IL17A

Product Details anti-IL17A Antibody Application Details Handling ProductDetails: References for anti-IL17A antibody (ABIN952921) Images back to top
Antigen
Alternative Name Interleukin-17A (IL17A) (IL17A Antibody Abstract)
Background The protein encoded by the IL17A gene is a proinflammatory cytokine produced by activated T cells. This cytokine regulates the activities of NF-kappaB and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO). High levels of this cytokine are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis.Synonyms: CTLA-8, CTLA8, Cytotoxic T-lymphocyte-associated antigen 8, IL-17, IL-17A, IL17
Gene ID 3605
NCBI Accession NP_002181
Research Area Cytokines, Receptors, Inflammation, Immunology, Virology, Cancer

Application Details

Product Details anti-IL17A Antibody Target Details IL17A Handling ProductDetails: References for anti-IL17A antibody (ABIN952921) Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-IL17A Antibody Target Details IL17A Application Details ProductDetails: References for anti-IL17A antibody (ABIN952921) Images back to top
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS with 0.09 % (W/V) Sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

ProductDetails: References for anti-IL17A antibody (ABIN952921)

Product Details anti-IL17A Antibody Target Details IL17A Application Details Handling Images back to top
Background publications

Chen, Xie, Cheng, Diao, Cheng, Liu, Xie, Chen, Zhu: "Role of interleukin-17 in lymphangiogenesis in non-small-cell lung cancer: Enhanced production of vascular endothelial growth factor C in non-small-cell lung carcinoma cells." in: Cancer science, Vol. 101, Issue 11, pp. 2384-90, 2010

Dart, Jankowska-Gan, Huang, Roenneburg, Keller, Torrealba, Rhoads, Kim, Bobadilla, Haynes, Wilkes, Burlingham, Greenspan: "Interleukin-17-dependent autoimmunity to collagen type V in atherosclerosis." in: Circulation research, Vol. 107, Issue 9, pp. 1106-16, 2010

Marwaha, Crome, Panagiotopoulos, Berg, Qin, Ouyang, Xu, Priatel, Levings, Tan: "Cutting edge: Increased IL-17-secreting T cells in children with new-onset type 1 diabetes." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 185, Issue 7, pp. 3814-8, 2010

Crome, Clive, Wang, Kang, Chow, Yu, Lai, Ghahary, Broady, Levings: "Inflammatory effects of ex vivo human Th17 cells are suppressed by regulatory T cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 185, Issue 6, pp. 3199-208, 2010

Images

Product Details anti-IL17A Antibody Target Details IL17A Application Details Handling ProductDetails: References for anti-IL17A antibody (ABIN952921) back to top
Supplier Images
Western Blotting (WB) image for anti-Interleukin 17A (IL17A) (AA 60-87), (Middle Region) antibody (ABIN952921) Western blot analysis of IL17A (arrow) using Interleukin-17A (IL17A) Antibody ; 293 c...