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anti-Mouse (Murine) IL17A antibody for Flow Cytometry

Recommended IL17A Antibody (supplied by: Log in to see )

Antigen
Interleukin 17A (IL17A) Antibodies
  • ChIL-17
  • Ctla-8
  • CTLA-8
  • CTLA8
  • Ctla8
  • IL-17
  • IL-17A
  • IL-17F
  • IL17
  • Il17
  • IL17A
Reactivity
Mouse (Murine)
430
188
63
10
5
5
1
Host
Rat
244
209
100
49
8
3
1
Clonality
Monoclonal
Conjugate
This IL17A antibody is conjugated to Alexa Fluor 700
70
35
32
24
17
15
15
11
10
10
8
7
7
7
7
7
7
5
5
5
4
4
4
3
3
2
2
2
2
2
2
2
1
1
Application
Flow Cytometry (FACS)
346
314
200
59
42
42
24
21
15
12
10
9
9
8
8
6
5
4
4
3
2
2
2
2
1
1
1
1
1
1
1
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Catalog No. ABIN2658105
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Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.28290245 ABIN2657538 FACS Alexa Fluor 488 Rat IgG1 kappa Log in to see TC11-18H10-1 11
0.28290245 ABIN2658881 FACS APC Rat IgG1 kappa Log in to see TC11-18H10-1 11
0.28290245 ABIN2659588 FACS IF WB PE-Cy7 Rat IgG1 kappa Log in to see TC11-18H10-1 11
0.28290245 ABIN2662100 FACS Pacific Blue Rat IgG1 kappa Log in to see TC11-18H10-1 11
0.28290245 ABIN2663988 FACS PE Rat IgG1 kappa Log in to see TC11-18H10-1 10
0.28290245 ABIN2660444 FACS PerCP-Cy5.5 Rat IgG1 kappa Log in to see TC11-18H10-1 11
0.28290245 ABIN2657944 FACS Alexa Fluor 647 Rat IgG1 kappa Log in to see TC11-18H10-1 11
0.28290245 ABIN2665115 FACS Rat IgG1 kappa Log in to see TC11-18H10-1 11
0.28290245 ABIN4896408 FACS Alexa Fluor 488 Rat IgG2b AA 22-158 Log in to see 881309
0.28290245 ABIN4896409 FACS Alexa Fluor 647 Rat IgG2b AA 22-158 Log in to see 881309
0.28290245 ABIN4899637 FACS Neut WB Goat IgG AA 22-158 Log in to see Polyclonal 10
0.28290245 ABIN4899638 FACS Rat IgG2b AA 22-158 Log in to see 881309
0.28290245 ABIN4896410 FACS PerCP Goat IgG AA 22-158 Log in to see Polyclonal
0.28290245 ABIN4896411 FACS Fluorescein Goat IgG AA 22-158 Log in to see Polyclonal
0.28290245 ABIN4896412 FACS PE Goat IgG AA 22-158 Log in to see Polyclonal 2
0.28290245 ABIN4324635 ELISA FACS WB Rat IgG2a kappa Log in to see 20B4-G10-F5
0.0010564557 ABIN738891 FACS IF (p) IHC (p) Rabbit IgG AA 110-150 Log in to see Polyclonal 3
0.0010564557 ABIN738898 FACS IF (p) FITC Rabbit IgG AA 110-150 Log in to see Polyclonal 1
0.0010564557 ABIN2661210 FACS Biotin Rat IgG1 kappa Log in to see TC11-8H4 10
0.0010564557 ABIN2665118 FACS Rat IgG1 kappa Log in to see TC11-18H10-1 11

Top referenced anti-IL17A antibody for Flow Cytometry

Similar anti-IL17A Antibodies

Application / Reactivity Mouse (Murine)
Biochemical Assay (BCA) 1 Antibodies
Blocking Antibody (Inhibition) 3 Antibodies
Confocal Microscopy (CM) 2 Antibodies
ELISA 110 Antibodies
Enzyme Immunoassay (EIA) 6 Antibodies
FLISA 1 Antibodies
Flow Cytometry (FACS) 83 Antibodies
Immunocytochemistry (ICC) 4 Antibodies
Immunofluorescence (IF) 16 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 12 Antibodies
Immunohistochemistry (IHC) 31 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 2 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 22 Antibodies
Immunoprecipitation (IP) 5 Antibodies

General

Antigen Interleukin 17A (IL17A) Antibodies
Reactivity Mouse (Murine)
(430), (188), (63), (10), (5), (5), (1)
Host Rat
(244), (209), (100), (49), (8), (3), (1)
Clonality (Clone)
Monoclonal   ( )
Conjugate This IL17A antibody is conjugated to Alexa Fluor 700
(70), (35), (32), (24), (17), (15), (15), (11), (10), (10), (8), (7), (7), (7), (7), (7), (7), (5), (5), (5), (4), (4), (4), (3), (3), (2), (2), (2), (2), (2), (2), (2), (1), (1)
Application Flow Cytometry (FACS)
(346), (314), (200), (59), (42), (42), (24), (21), (15), (12), (10), (9), (9), (8), (8), (6), (5), (4), (4), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1)
Pubmed 11 references available
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Product Details anti-IL17A Antibody

Target Details IL17A Application Details Handling References for anti-IL17A Antibody (ABIN2658105) Images
Purification The antibody was purified by affinity chromatography, and conjugated with Alexa Fluor® 700 under optimal conditions.
Clone TC11-18H10-1
Isotype IgG1 kappa

Target Details IL17A

Product Details anti-IL17A Antibody Application Details Handling References for anti-IL17A Antibody (ABIN2658105) Images back to top
Antigen
Alternative Name IL-17A (IL17A Antibody Abstract)
Background IL-17, also known as CTLA-8, is a T cell-expressed pleiotropic cytokine that exhibits a high degree of homology to a protein encoded by the ORF13 gene of herpes virus Saimiri. IL-17 is produced by Th cells (Th17) that are distinct from the traditional Th1- and Th2-cell subsets. IL-23 plays an important role in triggering IL-17 production. Both recombinant and natural IL-17 have been shown to exist as disulfide linked homodimers. IL-17 exhibits multiple biological activities on a variety of cells including: the induction of IL-6 and IL-8 production in fibroblasts, activation of NF-κB, and costimulation of T cell proliferation. IL-17 is an essential inflammatory mediator in the development of autoimmune diseases. Neutralization of IL-17 with monoclonal antibody is able to ameliorate the disease course.
Pathways TCR Signaling

Application Details

Product Details anti-IL17A Antibody Target Details IL17A Handling References for anti-IL17A Antibody (ABIN2658105) Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-IL17A Antibody Target Details IL17A Application Details References for anti-IL17A Antibody (ABIN2658105) Images back to top
Concentration 0.5 mg/mL
Buffer Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Protect from prolonged exposure to light. Do not freeze.
Storage 4 °C
Storage Comment The antibody solution should be stored undiluted between 2°C and 8°C

References for anti-IL17A Antibody (ABIN2658105)

Product Details anti-IL17A Antibody Target Details IL17A Application Details Handling Images back to top
Background publications

Smith, Stark, Zarbock, Burcin, Bruce, Vaswani, Foley, Ley: "IL-17A inhibits the expansion of IL-17A-producing T cells in mice through "short-loop" inhibition via IL-17 receptor." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 181, Issue 2, pp. 1357-64, 2008

Ehirchiou, Xiong, Xu, Chen, Shi, Zhang: "CD11b facilitates the development of peripheral tolerance by suppressing Th17 differentiation." in: The Journal of experimental medicine, Vol. 204, Issue 7, pp. 1519-24, 2007

Kang, Lim, Andrisani, Broxmeyer, Kim: "Vitamin A metabolites induce gut-homing FoxP3+ regulatory T cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 179, Issue 6, pp. 3724-33, 2007

Dong: "Diversification of T-helper-cell lineages: finding the family root of IL-17-producing cells." in: Nature reviews. Immunology, Vol. 6, Issue 4, pp. 329-33, 2006

Hofstetter, Ibrahim, Koczan, Kruse, Weishaupt, Toyka, Gold: "Therapeutic efficacy of IL-17 neutralization in murine experimental autoimmune encephalomyelitis." in: Cellular immunology, Vol. 237, Issue 2, pp. 123-30, 2006

Yen, Cheung, Scheerens, Poulet, McClanahan, McKenzie, Kleinschek, Owyang, Mattson, Blumenschein, Murphy, Sathe, Cua, Kastelein, Rennick: "IL-23 is essential for T cell-mediated colitis and promotes inflammation via IL-17 and IL-6." in: The Journal of clinical investigation, Vol. 116, Issue 5, pp. 1310-6, 2006

Schubert, Maier, Morawietz, Krenn, Kamradt: "Immunization with glucose-6-phosphate isomerase induces T cell-dependent peripheral polyarthritis in genetically unaltered mice." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 172, Issue 7, pp. 4503-9, 2004

Infante-Duarte, Horton, Byrne, Kamradt: "Microbial lipopeptides induce the production of IL-17 in Th cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 165, Issue 11, pp. 6107-15, 2000

Yao, Spriggs, Derry, Strockbine, Park, VandenBos, Zappone, Painter, Armitage: "Molecular characterization of the human interleukin (IL)-17 receptor." in: Cytokine, Vol. 9, Issue 11, pp. 794-800, 1998

Kennedy, Rossi, Zurawski, Vega, Kastelein, Wagner, Hannum, Zlotnik: "Mouse IL-17: a cytokine preferentially expressed by alpha beta TCR + CD4-CD8-T cells." in: Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research, Vol. 16, Issue 8, pp. 611-7, 1997

Fossiez, Djossou, Chomarat, Flores-Romo, Ait-Yahia, Maat, Pin, Garrone, Garcia, Saeland, Blanchard, Gaillard, Das Mahapatra, Rouvier, Golstein, Banchereau, Lebecque: "T cell interleukin-17 induces stromal cells to produce proinflammatory and hematopoietic cytokines." in: The Journal of experimental medicine, Vol. 183, Issue 6, pp. 2593-603, 1996

Images

Product Details anti-IL17A Antibody Target Details IL17A Application Details Handling References for anti-IL17A Antibody (ABIN2658105) back to top
Supplier Images
Flow Cytometry (FACS) image for anti-IL17A antibody (Interleukin 17A)  (Alexa Fluor 700) (ABIN2658105) anti-Interleukin 17A (IL17A) antibody (Alexa Fluor 700)