anti-Human IRF4 antibody for Enzyme Immunoassay

Recommended IRF4 Antibody (supplied by: Log in to see )

Antigen
Interferon Regulatory Factor 4 (IRF4) Antibodies
  • IRF4
  • irf4
  • LSIRF
  • MUM1
  • NF-EM5
  • AI385587
  • IRF-4
  • Spip
  • si:ch73-170d1.2
  • interferon regulatory factor 4
  • Interferon regulatory factor 4
  • interferon regulatory factor 4a
  • melanoma associated antigen (mutated) 1
  • IRF4
  • irf4
  • LOC100223845
  • Irf4
  • irf4a
  • MUM1
Epitope
AA 171-199, Middle Region
28
8
7
6
6
5
5
4
3
3
2
2
1
1
1
1
1
1
1
1
1
1
Reactivity
Human
138
48
25
5
5
5
4
4
4
3
2
2
2
2
1
Host
Rabbit
89
24
17
9
2
Clonality
Polyclonal
Conjugate
This IRF4 antibody is un-conjugated
3
2
2
1
1
1
1
1
Application
Enzyme Immunoassay (EIA), Flow Cytometry (FACS), Western Blotting (WB)
120
53
36
30
19
15
10
3
3
3
3
3
1
Supplier
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Catalog No. ABIN952951
$ 390.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN5554290 EIA WB Rabbit C-Term Log in to see Polyclonal
1 ABIN614626 EIA IHC (p) WB Mouse IgG2a AA 342-452 Log in to see 2F2
1 ABIN5555631 EIA WB Goat C-Term Log in to see Polyclonal

General

Antigen Interferon Regulatory Factor 4 (IRF4) Antibodies
Epitope AA 171-199, Middle Region
(28), (8), (7), (6), (6), (5), (5), (4), (3), (3), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human
(138), (48), (25), (5), (5), (5), (4), (4), (4), (3), (2), (2), (2), (2), (1)
Host Rabbit
(89), (24), (17), (9), (2)
Clonality
Polyclonal
Conjugate This IRF4 antibody is un-conjugated
(3), (2), (2), (1), (1), (1), (1), (1)
Application Enzyme Immunoassay (EIA), Flow Cytometry (FACS), Western Blotting (WB)
(120), (53), (36), (30), (19), (15), (10), (3), (3), (3), (3), (3), (1)
Pubmed 2 references available
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Product Details anti-IRF4 Antibody

Target Details IRF4 Application Details Handling ProductDetails: References for anti-IRF4 antibody (ABIN952951) Images
Specificity This antibody recognizes Human IRF4 (Center).
Purification Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS
Immunogen KLH conjugated synthetic peptide between 171-199 amino acids from the Central region of human IRF4
Isotype Ig

Target Details IRF4

Product Details anti-IRF4 Antibody Application Details Handling ProductDetails: References for anti-IRF4 antibody (ABIN952951) Images back to top
Antigen
Alternative Name IRF4 (IRF4 Antibody Abstract)
Background The protein encoded by this gene belongs to the IRF (interferon regulatory factor) family of transcription factors, characterized by an unique tryptophan pentad repeat DNA-binding domain. The IRFs are important in the regulation of interferons in response to infection by virus, and in the regulation of interferon-inducible genes. This family member is lymphocyte specific and negatively regulates Toll-like-receptor (TLR) signaling that is central to the activation of innate and adaptive immune systems. A chromosomal translocation involving this gene and the IgH locus, t(6,14)(p25,q32), may be a cause of multiple myeloma. Alternatively spliced transcript variants have been found for this gene.Synonyms: Interferon regulatory factor 4, LSIRF, Lymphocyte-specific interferon regulatory factor, MUM1, Multiple myeloma oncogene 1, NF-EM5
Molecular Weight 51772 Da
Gene ID 3662
NCBI Accession NP_001182215
Pathways Chromatin Binding

Application Details

Product Details anti-IRF4 Antibody Target Details IRF4 Handling ProductDetails: References for anti-IRF4 antibody (ABIN952951) Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-IRF4 Antibody Target Details IRF4 Application Details ProductDetails: References for anti-IRF4 antibody (ABIN952951) Images back to top
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS containing 0.09 % (W/V) Sodium Azide as preservative
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

ProductDetails: References for anti-IRF4 antibody (ABIN952951)

Product Details anti-IRF4 Antibody Target Details IRF4 Application Details Handling Images back to top
Background publications

Staudt, Bothur, Klein, Lingnau, Reuter, Grebe, Gerlitzki, Hoffmann, Ulges, Taube, Dehzad, Becker, Stassen, Steinborn, Lohoff, Schild, Schmitt, Bopp: "Interferon-regulatory factor 4 is essential for the developmental program of T helper 9 cells." in: Immunity, Vol. 33, Issue 2, pp. 192-202, 2010

Ucisik-Akkaya, Davis, Do, Morrison, Stemmer, Amadio, Dorak: "Examination of genetic polymorphisms in newborns for signatures of sex-specific prenatal selection." in: Molecular human reproduction, Vol. 16, Issue 10, pp. 770-7, 2010

Images

Product Details anti-IRF4 Antibody Target Details IRF4 Application Details Handling ProductDetails: References for anti-IRF4 antibody (ABIN952951) back to top
Supplier Images
Flow Cytometry (FACS) image for anti-Interferon Regulatory Factor 4 (IRF4) (AA 171-199), (Middle Region) antibody (ABIN952951) Flow cytometric analysis of 293 cells using IRF4 Antibody (Center) Cat.-No AP52236PU-...
Western Blotting (WB) image for anti-Interferon Regulatory Factor 4 (IRF4) (AA 171-199), (Middle Region) antibody (ABIN952951) Western blot analysis of IRF4 (arrow) using IRF4 Antibody (Center) Cat.-No AP52236PU-...