anti-Human TGFB1 antibody for Neutralization

Recommended TGFB1 Antibody (supplied by: Log in to see )

Antigen
Transforming Growth Factor, beta 1 (TGFB1) Antibodies
  • TGF-beta
  • ai39657
  • tgfb1
  • wu:fb13a07
  • xx:ai39657
  • TGFB
  • TGFbeta
  • TGFB1
  • TGFBI
  • csd
  • cdb1
  • cdg2
  • csd1
  • csd2
  • csd3
  • ebmd
  • lcd1
  • bigh3
  • cdgg1
  • betaig-h3
  • MGC146225
  • TGFB4
  • CED
  • DPD1
  • LAP
  • TGF-BETA-1
  • Tgfb
  • TGF-beta1
  • TGFbeta1
  • Tgfb-1
  • TGF-beta5
  • ced
  • dpd1
  • lap
  • tgf-beta
  • tgfb
  • tgfb5
  • tgfbeta
  • tgf
  • transforming growth factor, beta 1
  • transforming growth factor, beta 1a
  • transforming growth factor, beta-induced, 68kDa
  • transforming growth factor beta 1
  • TGFB1
  • tgfb1a
  • TGFBI
  • tgfbi
  • LOC100227786
  • Tgfb1
  • tgfb1
  • tgf
Reactivity
Human
344
134
85
29
19
15
12
11
11
11
10
6
6
4
3
3
3
2
2
1
Host
Mouse
248
190
15
4
3
2
1
Clonality
Monoclonal
Conjugate
This TGFB1 antibody is un-conjugated
35
26
16
12
10
10
9
8
8
8
7
7
6
6
3
3
3
3
3
3
3
2
2
2
2
2
2
2
1
1
1
Application
Enzyme Immunoassay (EIA), Immunohistochemistry (Frozen Sections) (IHC (fro)), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Neutralization (Neut), Western Blotting (WB)
275
228
135
126
63
42
39
34
16
15
14
12
11
4
3
2
2
2
2
2
2
1
1
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Catalog No. ABIN1109227
$ 665.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN285131 ICC FACS IHC Neut ELISA WB Goat IgG Log in to see Polyclonal
1 ABIN1826485 ICC FACS Neut IHC ELISA WB Goat IgG Log in to see Polyclonal
1 ABIN214914 FACS IHC Neut ELISA WB Biotin Mouse IgG1 Log in to see 2AR2
1 ABIN226266 FACS IHC Neut ELISA WB Mouse IgG1 AA 279-390 Log in to see 2AR2
1 ABIN4247389 BP CyTOF FACS Neut Mouse IgG1 Log in to see MM0446-6G14
1 ABIN2379744 FACS Neut IHC ELISA WB Biotin Mouse IgG1 Log in to see 2Ar2
1 ABIN1983333 FACS Neut Mouse IgG1 AA 30-278 Log in to see MM0446-6G14
1 ABIN2967589 FACS Neut IHC ELISA WB Mouse IgG1 Log in to see 2Ar2
1 ABIN4247393 BP FACS Neut PerCP Mouse IgG1 Log in to see MM0446-6G14
1 ABIN293558 Neut ELISA Goat IgG Log in to see Polyclonal
1 ABIN199718 Func IHC Neut ELISA WB Mouse IgG1, kappa Log in to see
1 ABIN1967164 IHC (p) Neut ELISA WB Mouse IgG1, kappa Log in to see
1 ABIN2964389 Neut IHC (p) ELISA WB Mouse IgG1 kappa full length Log in to see
1 ABIN649009 IHC (fro) FACS Neut WB PE IgG1 Log in to see TB21

Top referenced anti-TGFB1 antibody for Neutralization

Similar anti-TGFB1 Antibodies

Application / Reactivity Human
Agonist (Agon) 2 Antibodies
Blocking Antibody (Inhibition) 1 Antibodies
Blocking Peptide (BP) 2 Antibodies
Cytometry by Time of Flight (CyTOF) 1 Antibodies
ELISA 174 Antibodies
ELISA (Capture) 1 Antibodies
Enzyme Immunoassay (EIA) 13 Antibodies
Flow Cytometry (FACS) 97 Antibodies
Functional Studies (Func) 4 Antibodies
Immunoassay (IA) 2 Antibodies
Immunochromatography (IC) 1 Antibodies
Immunocytochemistry (ICC) 17 Antibodies
Immunofluorescence (IF) 37 Antibodies
Immunofluorescence (fixed cells) (IF/ICC) 5 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 26 Antibodies
Immunohistochemistry (IHC) 96 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 9 Antibodies

General

Antigen Transforming Growth Factor, beta 1 (TGFB1) Antibodies
Reactivity Human
(344), (134), (85), (29), (19), (15), (12), (11), (11), (11), (10), (6), (6), (4), (3), (3), (3), (2), (2), (1)
Host Mouse
(248), (190), (15), (4), (3), (2), (1)
Clonality (Clone)
Monoclonal   ( )
Conjugate This TGFB1 antibody is un-conjugated
(35), (26), (16), (12), (10), (10), (9), (8), (8), (8), (7), (7), (6), (6), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1)
Application Enzyme Immunoassay (EIA), Immunohistochemistry (Frozen Sections) (IHC (fro)), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Neutralization (Neut), Western Blotting (WB)
(275), (228), (135), (126), (63), (42), (39), (34), (16), (15), (14), (12), (11), (4), (3), (2), (2), (2), (2), (2), (2), (1), (1)
Pubmed 5 references available
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Product Details anti-TGFB1 Antibody

Target Details TGFB1 Application Details Handling ProductDetails: References for anti-TGFB1 antibody (ABIN1109227) Images
Specificity The antibody detects human TGF beta 1 (and has been used in sheep, see "Applications"). Other species not tested. In flow cytometry this antibody detects the intracellular form of TGF-beta (so-called latent, LAP-bound or inactive TGF-beta) as well as with membrane bound TGF-beta (extracellular matrix form). Western blotting demonstrated that this antibody reacts with the dimeric (25 kDa) and monomeric (12,5 kDa) forms of TGF-beta (active form) under both non-reducing and reducing conditions respectively. In ELISA the antibody recognizes both human platelet-derived and recombinant TGF-beta.
Purification Affinity chromatography
Clone TB21
Isotype IgG1

Target Details TGFB1

Product Details anti-TGFB1 Antibody Application Details Handling ProductDetails: References for anti-TGFB1 antibody (ABIN1109227) Images back to top
Antigen
Alternative Name TGFB1 (TGFB1 Antibody Abstract)
Background Transforming Growth Factor-Beta (TGF-beta, TGFB) was originally identified for its ability to induce phenotypic transformation of fibroblasts in diverse cell types. This protein controls proliferation, differentiation, and many other functions of various cell types. TGFB is present on most cell types including T cells and monocytes.Synonyms: TGF-beta-1, TGFB, Transforming growth factor beta-1
Gene ID 7040
NCBI Accession NP_000651
UniProt P01137
Pathways EGFR Signaling Pathway, Dopaminergic Neurogenesis, Cellular Response to Molecule of Bacterial Origin, Glycosaminoglycan Metabolic Process, Regulation of Leukocyte Mediated Immunity, Regulation of Muscle Cell Differentiation, Positive Regulation of Immune Effector Process, Cell-Cell Junction Organization, Production of Molecular Mediator of Immune Response, Ribonucleoside Biosynthetic Process, Skeletal Muscle Fiber Development, Regulation of Carbohydrate Metabolic Process, Protein targeting to Nucleus, Autophagy

Application Details

Product Details anti-TGFB1 Antibody Target Details TGFB1 Handling ProductDetails: References for anti-TGFB1 antibody (ABIN1109227) Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-TGFB1 Antibody Target Details TGFB1 Application Details ProductDetails: References for anti-TGFB1 antibody (ABIN1109227) Images back to top
Buffer 0.01 M sodium phosphate, 0.15 M NaCl, pH 7.3, 0.2 % BSA, 0.09 % sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C
Storage Comment Store the antibody undiluted at 2-8 °C. Fluorochrome labelled product is photosensitive and should be protected from light.

ProductDetails: References for anti-TGFB1 antibody (ABIN1109227)

Product Details anti-TGFB1 Antibody Target Details TGFB1 Application Details Handling Images back to top
Background publications

Hodge, Hodge, Reynolds, Scicchitano, Holmes: "Increased production of TGF-beta and apoptosis of T lymphocytes isolated from peripheral blood in COPD." in: American journal of physiology. Lung cellular and molecular physiology, Vol. 285, Issue 2, pp. L492-9, 2003

Hodge, Hodge, Flower, Reynolds, Scicchitano, Holmes: "Up-regulation of production of TGF-beta and IL-4 and down-regulation of IL-6 by apoptotic human bronchial epithelial cells." in: Immunology and cell biology, Vol. 80, Issue 6, pp. 537-43, 2002

Garba, Pilcher, Bingham, Eron, Frelinger: "HIV antigens can induce TGF-beta(1)-producing immunoregulatory CD8+ T cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 168, Issue 5, pp. 2247-54, 2002

Crawford, Stellmach, Murphy-Ullrich, Ribeiro, Lawler, Hynes, Boivin, Bouck: "Thrombospondin-1 is a major activator of TGF-beta1 in vivo." in: Cell, Vol. 93, Issue 7, pp. 1159-70, 1998

Shi, Ye, Bao: "[Biological characterization of a monoclonal antibody TB 21 against human transforming growth factor-beta 1]." in: Shi yan sheng wu xue bao, Vol. 26, Issue 2, pp. 141-50, 1993

Images

Product Details anti-TGFB1 Antibody Target Details TGFB1 Application Details Handling ProductDetails: References for anti-TGFB1 antibody (ABIN1109227) back to top
Supplier Images
 image for anti-TGFB1 antibody (Transforming Growth Factor, beta 1) (ABIN1109227) anti-Transforming Growth Factor, beta 1 (TGFB1) antibody
 image for anti-TGFB1 antibody (Transforming Growth Factor, beta 1) (ABIN1109227) anti-Transforming Growth Factor, beta 1 (TGFB1) antibody (Image 2)