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anti-Human TGFB1 antibody for Neutralization

Recommended TGFB1 Antibody (supplied by: Log in to see )

Antigen
Transforming Growth Factor, beta 1 (TGFB1) Antibodies
  • ai39657
  • betaig-h3
  • bigh3
  • cdb1
  • cdg2
  • cdgg1
  • CED
  • ced
  • csd
  • csd1
  • csd2
  • csd3
  • DPD1
  • dpd1
  • ebmd
  • LAP
  • lap
  • lcd1
  • MGC146225
  • tgf
  • TGF-beta
  • tgf-beta
  • TGF-BETA-1
  • TGF-beta1
  • TGF-beta5
  • TGFB
  • Tgfb
  • tgfb
  • Tgfb-1
  • tgfb1
  • TGFB1
  • TGFB4
  • tgfb5
  • TGFbeta
  • tgfbeta
  • TGFbeta1
  • TGFBI
  • wu:fb13a07
  • xx:ai39657
Reactivity
Human
286
81
67
25
13
13
11
10
7
7
7
4
3
3
3
3
2
1
1
Host
Mouse
235
133
5
4
3
2
1
Clonality
Monoclonal
Conjugate
This TGFB1 antibody is un-conjugated
33
23
11
9
9
6
5
5
5
3
3
3
3
3
3
3
2
2
2
1
1
1
1
1
1
1
1
1
Application
Enzyme Immunoassay (EIA), Immunohistochemistry (Frozen Sections) (IHC (fro)), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Neutralization (Neut), Western Blotting (WB)
209
200
103
67
47
34
33
28
25
19
14
10
4
3
2
2
2
2
2
1
1
Supplier
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Catalog No. ABIN1109227
$ 654.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.00087235513 ABIN285131 ICC FACS IHC Neut ELISA WB Goat IgG Log in to see Polyclonal
0.00087235513 ABIN293558 Neut ELISA Goat IgG Log in to see Polyclonal
0.00087235513 ABIN226266 FACS IHC Neut ELISA WB Mouse IgG1 Log in to see
0.00087235513 ABIN199718 Func IHC Neut ELISA WB Mouse IgG1, kappa Log in to see
0.00087235513 ABIN214914 FACS IHC Neut ELISA WB Biotin Mouse IgG1 Log in to see
0.00087235513 ABIN1983333 FACS Neut Mouse IgG1 AA 30-278 Log in to see MM0446-6G14
0.00087235513 ABIN1826485 ICC FACS Neut IHC ELISA WB Goat IgG Log in to see Polyclonal
0.00087235513 ABIN2379744 FACS Neut IHC ELISA WB Biotin Mouse IgG1 Log in to see 2Ar2
0.00087235513 ABIN2967589 FACS Neut IHC ELISA WB Mouse IgG1 Log in to see 2Ar2
0.00087235513 ABIN1967164 IHC (p) Neut ELISA WB Mouse IgG1, kappa Log in to see
0.00087235513 ABIN4247389 BP FACS Neut Mouse IgG1 Log in to see MM0446-6G14
0.00087235513 ABIN4247390 BP FACS Neut DyLight 350 Mouse IgG1 Log in to see MM0446-6G14
0.00087235513 ABIN4247391 BP FACS Neut DyLight 405 Mouse IgG1 Log in to see MM0446-6G14
0.00087235513 ABIN4247392 BP FACS Neut PE Mouse IgG1 Log in to see MM0446-6G14
0.00087235513 ABIN4247393 BP FACS Neut PerCP Mouse IgG1 Log in to see MM0446-6G14
0.00087235513 ABIN4247394 BP FACS Neut Allophycocyanin Mouse IgG1 Log in to see MM0446-6G14
0.00087235513 ABIN4247395 BP FACS Neut DyLight 755 Mouse IgG1 Log in to see MM0446-6G14
0.00087235513 ABIN4247396 BP FACS Neut DyLight 488 Mouse IgG1 Log in to see MM0446-6G14
0.00087235513 ABIN4247397 BP FACS Neut DyLight 405LS Mouse IgG1 Log in to see MM0446-6G14
0.00087235513 ABIN4247398 BP FACS Neut DyLight 680 Mouse IgG1 Log in to see MM0446-6G14

Top referenced anti-TGFB1 antibody for Neutralization

Similar anti-TGFB1 Antibodies

Application / Reactivity Human
Agonist (Agon) 2 Antibodies
Blocking Antibody (Inhibition) 1 Antibodies
ELISA 151 Antibodies
ELISA (Capture) 1 Antibodies
Enzyme Immunoassay (EIA) 11 Antibodies
Flow Cytometry (FACS) 60 Antibodies
Functional Studies (Func) 4 Antibodies
Immunochromatography (IC) 1 Antibodies
Immunocytochemistry (ICC) 14 Antibodies
Immunofluorescence (IF) 31 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 22 Antibodies
Immunohistochemistry (IHC) 86 Antibodies
Immunohistochemistry (Acetone-fixed) (IHC (af)) 2 Antibodies
Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp)) 3 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 9 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 36 Antibodies
Immunoprecipitation (IP) 3 Antibodies

General

Antigen Transforming Growth Factor, beta 1 (TGFB1) Antibodies
Reactivity Human
(286), (81), (67), (25), (13), (13), (11), (10), (7), (7), (7), (4), (3), (3), (3), (3), (2), (1), (1)
Host Mouse
(235), (133), (5), (4), (3), (2), (1)
Clonality (Clone)
Monoclonal   ( )
Conjugate This TGFB1 antibody is un-conjugated
(33), (23), (11), (9), (9), (6), (5), (5), (5), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Enzyme Immunoassay (EIA), Immunohistochemistry (Frozen Sections) (IHC (fro)), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Neutralization (Neut), Western Blotting (WB)
(209), (200), (103), (67), (47), (34), (33), (28), (25), (19), (14), (10), (4), (3), (2), (2), (2), (2), (2), (1), (1)
Pubmed 5 references available
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Product Details anti-TGFB1 Antibody

Target Details TGFB1 Application Details Handling References for anti-TGFB1 Antibody (ABIN1109227) Images
Specificity The antibody detects human TGF beta 1 (and has been used in sheep, see "Applications"). Other species not tested. In flow cytometry this antibody detects the intracellular form of TGF-beta (so-called latent, LAP-bound or inactive TGF-beta) as well as with membrane bound TGF-beta (extracellular matrix form). Western blotting demonstrated that this antibody reacts with the dimeric (25 kDa) and monomeric (12,5 kDa) forms of TGF-beta (active form) under both non-reducing and reducing conditions respectively. In ELISA the antibody recognizes both human platelet-derived and recombinant TGF-beta.
Purification Affinity chromatography
Clone TB21
Isotype IgG1

Target Details TGFB1

Product Details anti-TGFB1 Antibody Application Details Handling References for anti-TGFB1 Antibody (ABIN1109227) Images back to top
Antigen
Alternative Name TGFB1 (TGFB1 Antibody Abstract)
Background Transforming Growth Factor-Beta (TGF-beta, TGFB) was originally identified for its ability to induce phenotypic transformation of fibroblasts in diverse cell types. This protein controls proliferation, differentiation, and many other functions of various cell types. TGFB is present on most cell types including T cells and monocytes.Synonyms: TGF-beta-1, TGFB, Transforming growth factor beta-1
Gene ID 7040
NCBI Accession NP_000651
UniProt P01137
Pathways TCR Signaling, ACE Inhibitor Pathway, EGFR Signaling Pathway

Application Details

Product Details anti-TGFB1 Antibody Target Details TGFB1 Handling References for anti-TGFB1 Antibody (ABIN1109227) Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-TGFB1 Antibody Target Details TGFB1 Application Details References for anti-TGFB1 Antibody (ABIN1109227) Images back to top
Buffer 0.01 M sodium phosphate, 0.15 M NaCl, pH 7.3, 0.2 % BSA, 0.09 % sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C
Storage Comment Store the antibody undiluted at 2-8 °C. Fluorochrome labelled product is photosensitive and should be protected from light.

References for anti-TGFB1 Antibody (ABIN1109227)

Product Details anti-TGFB1 Antibody Target Details TGFB1 Application Details Handling Images back to top
Background publications

Hodge, Hodge, Reynolds, Scicchitano, Holmes: "Increased production of TGF-beta and apoptosis of T lymphocytes isolated from peripheral blood in COPD." in: American journal of physiology. Lung cellular and molecular physiology, Vol. 285, Issue 2, pp. L492-9, 2003

Hodge, Hodge, Flower, Reynolds, Scicchitano, Holmes: "Up-regulation of production of TGF-beta and IL-4 and down-regulation of IL-6 by apoptotic human bronchial epithelial cells." in: Immunology and cell biology, Vol. 80, Issue 6, pp. 537-43, 2002

Garba, Pilcher, Bingham, Eron, Frelinger: "HIV antigens can induce TGF-beta(1)-producing immunoregulatory CD8+ T cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 168, Issue 5, pp. 2247-54, 2002

Crawford, Stellmach, Murphy-Ullrich, Ribeiro, Lawler, Hynes, Boivin, Bouck: "Thrombospondin-1 is a major activator of TGF-beta1 in vivo." in: Cell, Vol. 93, Issue 7, pp. 1159-70, 1998

Shi, Ye, Bao: "[Biological characterization of a monoclonal antibody TB 21 against human transforming growth factor-beta 1]." in: Shi yan sheng wu xue bao, Vol. 26, Issue 2, pp. 141-50, 1993

Images

Product Details anti-TGFB1 Antibody Target Details TGFB1 Application Details Handling References for anti-TGFB1 Antibody (ABIN1109227) back to top
Supplier Images
 image for anti-TGFB1 antibody (Transforming Growth Factor, beta 1) (ABIN1109227) anti-Transforming Growth Factor, beta 1 (TGFB1) antibody
 image for anti-TGFB1 antibody (Transforming Growth Factor, beta 1) (ABIN1109227) anti-Transforming Growth Factor, beta 1 (TGFB1) antibody (Image 2)