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Browse our Replication Factor C (Activator 1) 3, 38kDa Proteins (RFC3)

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Replication Factor C (Activator 1) 3, 38kDa Proteins (RFC3)
On www.antibodies-online.com are 8 Replication Factor C (Activator 1) 3, 38kDa (RFC3) Proteins from 4 different suppliers available. Additionally we are shipping Replication Factor C (Activator 1) 3, 38kDa Antibodies (56) and many more products for this protein. A total of 76 Replication Factor C (Activator 1) 3, 38kDa products are currently listed.
Synonyms:
21.m02902, 38kDa, 2810416I22Rik, AU022547, cb275, CG5313, Dmel\\CG5313, DmRFC3, DRFC, Recc3, Rfc3, RFC38
list all proteins Gene Name GeneID UniProt
RFC3 69263 Q8R323
Rat RFC3 RFC3 288414  
RFC3 5983 P40938

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More Proteins for Replication Factor C (Activator 1) 3, 38kDa Interaction Partners

Mouse (Murine) Replication Factor C (Activator 1) 3, 38kDa (RFC3) interaction partners

Human Replication Factor C (Activator 1) 3, 38kDa (RFC3) interaction partners

  1. The expression level of RFC3 was markedly upregulated in the HCC (show FAM126A Proteins) tissues and cells.

  2. The expression level of RFC3 was remarkably up-regulated in ovarian cancer OVCAR-3 cells. Down-regulation of RFC3 expression arrested the cell cycle of OVCAR-3 cell in the S-phase and induced apoptosis.

  3. High RFC3 expression is associated with neoplastic myelopoiesis.

  4. our findings suggest that RFC3 protein is an important and independent biomarker with prognostic implications for patients with ovarian carcinoma.

  5. 9-cis-RA-activated RXRalpha (show RXRA Proteins) suppresses the growth of retinoid-sensitive breast cancer and embryonic cells through RFC3.

  6. Data identified RFC3 as a candidate oncogene (show RAB1A Proteins) amplified in esophageal adenocarcinoma (EAC (show CYLD Proteins)).

  7. RFC3 mutation and loss of RFC3 expression occur in large fractions of gastric and colorectal cancers and suggest that these alterations may contribute to the cancer pathogenesis by deregulating DNA repair and replication.

Replication Factor C (Activator 1) 3, 38kDa (RFC3) Protein Profile

Protein Summary

The elongation of primed DNA templates by DNA polymerase delta and DNA polymerase epsilon requires the accessory proteins proliferating cell nuclear antigen (PCNA) and replication factor C (RFC). RFC, also named activator 1, is a protein complex consisting of five distinct subunits of 140, 40, 38, 37, and 36 kDa. This gene encodes the 38 kDa subunit. This subunit is essential for the interaction between the 140 kDa subunit and the core complex that consists of the 36, 37, and 40 kDa subunits. Alternatively spliced transcript variants encoding distinct isoforms have been described.

Alternative names and synonyms associated with Replication Factor C (Activator 1) 3, 38kDa (RFC3)

  • Replication factor C subunit 3 (RfC3)
  • replication factor C3 (PF14_0601)
  • replication factor C3 (Chro.30359)
  • replication factor C3 (PB000006.01.0)
  • replication factor C3 (PC000345.04.0)
  • replication factor C subunit 3 (TP04_0380)
  • replication factor C subunit 3 (Tb09.211.3310)
  • replication factor C3 (PY04255)
  • replication factor C3 (PVX_117300)
  • replication factor C 38 kDa subunit (BBOV_IV003080)
  • replication factor C subunit 3 (SJAG_02182)
  • replication factor C3 (PKH_124240)
  • replication factor C (activator 1) 3 (rfc3)
  • replication factor C (activator 1) 3 (Rfc3)
  • replication factor C (activator 1) 3, 38kDa (RFC3)
  • replication factor C (activator 1) 3, 38kDa (rfc3)
  • 21.m02902 protein
  • 38kDa protein
  • 2810416I22Rik protein
  • AU022547 protein
  • cb275 protein
  • CG5313 protein
  • Dmel\\CG5313 protein
  • DmRFC3 protein
  • DRFC protein
  • Recc3 protein
  • Rfc3 protein
  • RFC38 protein

Protein level used designations for RFC3

replication factor C subunit 3 , CG5313-PA , RfC3-PA , drosophila replication factor C , replication factor C3 , A1 38 kDa subunit , RF-C 38 kDa subunit , RFC38 , activator 1 38 kDa subunit , activator 1 subunit 3 , replication factor C 3 , replication factor C 38 kDa subunit , replication factor C, 38 kDa , RFC, 38 kD subunit

GENE ID SPECIES
34423 Drosophila melanogaster
812183 Plasmodium falciparum 3D7
3414135 Cryptosporidium hominis TU502
3423971 Plasmodium berghei ANKA
3497339 Plasmodium chabaudi chabaudi
3501169 Theileria parva strain Muguga
3660934 Trypanosoma brucei brucei strain 927/4 GUTat10.1
3789846 Plasmodium yoelii yoelii 17XNL
5475053 Plasmodium vivax Sal-1
5477691 Babesia bovis T2Bo
7050157 Schizosaccharomyces japonicus yFS275
7322003 Plasmodium knowlesi strain H
100528456 Ictalurus punctatus
69263 Mus musculus
288414 Rattus norvegicus
259256 Danio rerio
5983 Homo sapiens
734626 Xenopus laevis
418907 Gallus gallus
477308 Canis lupus familiaris
515602 Bos taurus
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