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Browse our ECSIT Proteins (ECSIT)

Full name:
ECSIT Homolog (Drosophila) Proteins (ECSIT)
On www.antibodies-online.com are 12 ECSIT Homolog (Drosophila) (ECSIT) Proteins from 6 different suppliers available. Additionally we are shipping ECSIT Antibodies (65) and many more products for this protein. A total of 82 ECSIT products are currently listed.
Synonyms:
CG10610, dECSIT, DmECSIT, Dmel\\CG10610, ECSIT, SITPEC
list all proteins Gene Name GeneID UniProt
ECSIT 26940 Q9QZH6
ECSIT 51295 Q9BQ95
Rat ECSIT ECSIT 300447 Q5XIC2

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ECSIT Proteins (ECSIT) by Origin

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Top referenced ECSIT Proteins

  1. Human ECSIT Protein expressed in Escherichia coli (E. coli) - ABIN1098409 : Moustakas, Heldin: Ecsit-ement on the crossroads of Toll and BMP signal transduction. in Genes & development 2003 (PubMed)
    Show all 2 references for ABIN1098409

  2. Human ECSIT Protein expressed in Escherichia coli (E. coli) - ABIN2006206 : Gerhard, Wagner, Feingold, Shenmen, Grouse, Schuler, Klein, Old, Rasooly, Good, Guyer, Peck, Derge, Lipman, Collins, Jang, Sherry, Feolo, Misquitta, Lee, Rotmistrovsky, Greenhut, Schaefer, Buetow et al.: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). ... in Genome research 2004 (PubMed)
    Show all 2 references for ABIN2006206

More Proteins for ECSIT Interaction Partners

Mouse (Murine) ECSIT Homolog (Drosophila) (ECSIT) interaction partners

  1. functions as an essential component in two important signal transduction pathways and establishes a novel role for Ecsit as a cofactor for Smad proteins in the bone morphogenetic protein signaling pathway

Human ECSIT Homolog (Drosophila) (ECSIT) interaction partners

  1. mediates virus-triggered type I IFN induction by bridging RIG-I (show DDX58 Proteins) and MDA5 (show IFIH1 Proteins) to the VISA (show MAVS Proteins) complex

  2. Ubiquitination of ECSIT might have a role in the regulation of NF-kappaB (show NFKB1 Proteins) activity in TLR4 (show TLR4 Proteins) signaling.

  3. Authors conclude that ECSIT appears to be a novel Hepatitis B virus X protein-interacting signal molecule (show WNT4 Proteins) and their interaction is mechanistically important in IL-1beta (show IL1B Proteins) induction of NF-kappaB (show NFKB1 Proteins) activation.

  4. Data show that the ECSIT (evolutionarily conserved signaling intermediate in Toll (show TLR4 Proteins) pathways) complex, including MEKK7 (TAK1 (show MAP3K7 Proteins)) and TNF receptor-associated factor 6 (TRAF6 (show TRAF6 Proteins)), plays a role in Toll-like receptor 4 (show TLR4 Proteins) -mediated signals to activate NF-kappa B (show NFKB1 Proteins).

  5. TRIM59 interacts with ECSIT as an adaptor protein required for the TLR-mediated transduction pathway.

  6. Study shows a mitochondrial function for Ecsit in the assembly of mitochondrial complex I, an N-terminal targeting signal directs Ecsit to mitochondria, where it interacts with assembly chaperone NDUFAF1 (show NDUFAF1 Proteins).

ECSIT Protein Profile

Protein Summary

Adapter protein of the Toll-like and IL-1 receptor signaling pathway that is involved in the activation of NF-kappa- B. Required for efficient assembly of mitochondrial NADH:ubiquinone oxidoreductase (By similarity).

Alternative names and synonyms associated with ECSIT

  • CG10610 gene product from transcript CG10610-RA (ECSIT)
  • ECSIT homolog (Drosophila) (ECSIT)
  • ecsit (CpipJ_CPIJ003637)
  • evolutionarily conserved signaling intermediate in Toll pathway (LOC100355017)
  • ECSIT homolog (Drosophila) (Ecsit)
  • ECSIT signalling integrator (ECSIT)
  • ECSIT signalling integrator (Ecsit)
  • ECSIT signalling integrator (ecsit)
  • CG10610 protein
  • dECSIT protein
  • DmECSIT protein
  • Dmel\\CG10610 protein
  • ECSIT protein
  • SITPEC protein

Protein level used designations for ECSIT

CG10610-PA , ECSIT-PA , ECSIT homolog (Drosophila) , evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial-like , ecsit , evolutionarily conserved signaling intermediate in Toll pathway , evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial , signaling intermediate in Toll pathway-evolutionarily conserved , ECSIT homolog , likely ortholog of mouse signaling intermediate in Toll pathway evolutionarily conserved

GENE ID SPECIES
40732 Drosophila melanogaster
455733 Pan troglodytes
484938 Canis lupus familiaris
100391798 Callithrix jacchus
6035186 Culex quinquefasciatus
100355017 Oryctolagus cuniculus
26940 Mus musculus
507245 Bos taurus
51295 Homo sapiens
300447 Rattus norvegicus
100037194 Xenopus laevis
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