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Browse our anti-IRAK3 (IRAK3) Antibodies

Full name:
anti-Interleukin-1 Receptor-Associated Kinase 3 Antibodies (IRAK3)
On are 144 Interleukin-1 Receptor-Associated Kinase 3 (IRAK3) Antibodies from 25 different suppliers available. Additionally we are shipping IRAK3 Kits (12) and IRAK3 Proteins (8) and many more products for this protein. A total of 178 IRAK3 products are currently listed.
4833428C18Rik, AI563835, ASRT5, IRAK-M, IRAK3, IrakM, si:dkey-150i15.2
list all antibodies Gene Name GeneID UniProt
IRAK3 11213 Q9Y616
IRAK3 73914 Q8K4B2
IRAK3 314870  

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Most Popular Reactivities for anti-IRAK3 (IRAK3) Antibodies

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anti-Human IRAK3 Antibodies:

anti-Mouse (Murine) IRAK3 Antibodies:

anti-Rat (Rattus) IRAK3 Antibodies:

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Top referenced anti-IRAK3 Antibodies

  1. Human Polyclonal IRAK3 Primary Antibody for EIA, IHC (p) - ABIN401363 : Cao, Henzel, Gao: IRAK: a kinase associated with the interleukin-1 receptor. in Science (New York, N.Y.) 1996 (PubMed)
    Show all 3 references for ABIN401363

  2. Human Polyclonal IRAK3 Primary Antibody for EIA, WB - ABIN360119 : Rosati, Martin: Identification and characterization of murine IRAK-M. in Biochemical and biophysical research communications 2002 (PubMed)
    Show all 2 references for ABIN360119

  3. Cow (Bovine) Polyclonal IRAK3 Primary Antibody for WB - ABIN2779025 : del Fresno, Otero, Gómez-García, González-León, Soler-Ranger, Fuentes-Prior, Escoll, Baos, Caveda, García, Arnalich, López-Collazo: Tumor cells deactivate human monocytes by up-regulating IL-1 receptor associated kinase-M expression via CD44 and TLR4. in Journal of immunology (Baltimore, Md. : 1950) 2005 (PubMed)

  4. Rat (Rattus) Polyclonal IRAK3 Primary Antibody for ELISA, WB - ABIN308416 : Balaci, Spada, Olla, Sole, Loddo, Anedda, Naitza, Zuncheddu, Maschio, Altea, Uda, Pilia, Sanna, Masala, Crisponi, Fattori, Devoto, Doratiotto, Rassu, Mereu, Giua, Cadeddu, Atzeni, Pelosi, Corrias et al.: IRAK-M is involved in the pathogenesis of early-onset persistent asthma. ... in American journal of human genetics 2007 (PubMed)

More Antibodies against IRAK3 Interaction Partners

Human Interleukin-1 Receptor-Associated Kinase 3 (IRAK3) interaction partners

  1. Alpha-Melanocyte-Stimulating Hormone (show POMC Antibodies) Suppresses TLR2 (show TLR2 Antibodies)-Mediated Functional Responses through IRAK-M in Normal Human Keratinocytes

  2. IRAK3 methylation was associated with tumor stage and poor prognosis of hepatocellular carcinoma patients.

  3. The structure function of the death domain of human IRAK-M

  4. HIF1alpha (show HIF1A Antibodies) is a regulator of monocyte functional re-programming in sepsis via regulating IRAKM expression.

  5. IRAK-M expression is upregulated in peripheral blood cells from idiopathic pulmonary fibrosis patients

  6. our study demonstrates that patients carrying IRAK-M+22148 G haplotype are more susceptible to sepsis than patients carrying IRAK-M+22148 A haplotype, suggesting that IRAK-M+22148 G haplotype might be a risk factor for sepsis.

  7. These data indicate the enhancing effect of IRAK-M on epithelial human rhinovirus-16 infection, which is partly through the autophagic pathway.

  8. IRAK-M mediates TLR7 (show TLR7 Antibodies)-induced MEKK3 (show MAP3K3 Antibodies)-dependent second wave NFjB activation to produce inhibitory molecules

  9. the tested variations of IRAK-M and SIGIRR (show SIGIRR Antibodies) genes do not confer a relevant role in the susceptibility to systemic lupus erythematosus in European-descent populations

  10. these data identify an important signaling regulator in human macrophages that is used by surfactant to control the long-term alveolar inflammatory response, i.e., enhanced IRAK-M activity.

Mouse (Murine) Interleukin-1 Receptor-Associated Kinase 3 (IRAK3) interaction partners

  1. These data demonstrate LTi cells are present in the stomach and promote lymphoid follicle formation in response to infection, but are limited by IRAK-M expression.

  2. IL-7 (show IL7 Antibodies) reduced IRAK-M expression and attenuated immune tolerance induced by either LPS (show TLR4 Antibodies) or CpGA

  3. the results suggest that IRAK-M may be targeted by L. donovani to inhibit TLR-mediated proinflammatory response late during in vitro infection.

  4. These data indicate expression of IRAK-M skews lung macrophages toward an alternatively activated profibrotic phenotype, which promotes collagen production, leading to the progression of experimental pulmonary fibrosis.

  5. Our study identifies the DAP12 (show TYROBP Antibodies)/IRAK-M/IL-10 (show IL10 Antibodies) to be a novel molecular pathway in APCs (show APCS Antibodies) exploited by mycobacterial pathogens, allowing infection a foothold in the lung.

  6. This study illustrates how the modulation of innate immune pathways through IRAK-M influences the development of autoimmune diabetes.

  7. novel findings provide new insights into the understanding of negative regulatory mechanisms of the TLR4 (show TLR4 Antibodies) signaling pathway.

  8. Altered gut (show GUSB Antibodies) microbiota promotes colitis-associated cancer in IL-1 receptor-associated kinase M-deficient mice.

  9. IRAK-M plays an important role in alcohol-induced liver injury and IRAK-M negatively regulates the innate and possibly the adaptive immune response in the liver reacting to acute insult by alcohol.

  10. debris-induced IRAK-M decreases foreign body reactions, but at the same time, the over-expression of IRAK-M may also be detrimental on local intrusion of PAMPs or bacteria

IRAK3 Antigen Profile

Antigen Summary

This gene encodes a member of the interleukin-1 receptor-associated kinase protein family. Members of this family are essential components of the Toll/IL-R immune signal transduction pathways. This protein is primarily expressed in monocytes and macrophages and functions as a negative regulator of Toll-like receptor signaling. Mutations in this gene are associated with a susceptibility to asthma. Alternate splicing results in multiple transcript variants.

Alternative names and synonyms associated with IRAK3

  • interleukin-1 receptor-associated kinase 3 (IRAK3) antibody
  • interleukin-1 receptor-associated kinase 3 (irak3) antibody
  • interleukin-1 receptor-associated kinase 3 (Irak3) antibody
  • 4833428C18Rik antibody
  • AI563835 antibody
  • ASRT5 antibody
  • IRAK-M antibody
  • IRAK3 antibody
  • IrakM antibody
  • si:dkey-150i15.2 antibody

Protein level used designations for IRAK3

interleukin-1 receptor-associated kinase 3 , interleukin-1 receptor-associated kinase 3-like , IL-1 receptor-associated kinase M , interleukin-1 receptor-associated kinase M , IRAK-3

100441850 Pongo abelii
100483119 Ailuropoda melanoleuca
467058 Pan troglodytes
481150 Canis lupus familiaris
567444 Danio rerio
717845 Macaca mulatta
100024979 Monodelphis domestica
100583020 Nomascus leucogenys
11213 Homo sapiens
510342 Bos taurus
73914 Mus musculus
314870 Rattus norvegicus
100514645 Sus scrofa
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