Browse our anti-Pellino E3 Ubiquitin Protein Ligase Family Member 3 (PELI3) Antibodies

Full name:
anti-Pellino E3 Ubiquitin Protein Ligase Family Member 3 Antibodies (PELI3)
On www.antibodies-online.com are 39 Pellino E3 Ubiquitin Protein Ligase Family Member 3 (PELI3) Antibodies from 12 different suppliers available. Additionally we are shipping Pellino E3 Ubiquitin Protein Ligase Family Member 3 Proteins (4) and and many more products for this protein. A total of 49 Pellino E3 Ubiquitin Protein Ligase Family Member 3 products are currently listed.
Synonyms:
6030441F14Rik, A930011L17, BC028931, RGD1305989
list all antibodies Gene Name GeneID UniProt
PELI3 240518 Q8BXR6
PELI3 246330 Q8N2H9
PELI3 309157  

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Most Popular Reactivities for anti-Pellino E3 Ubiquitin Protein Ligase Family Member 3 (PELI3) Antibodies

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Top referenced anti-Pellino E3 Ubiquitin Protein Ligase Family Member 3 Antibodies

  1. Cow (Bovine) Polyclonal PELI3 Primary Antibody for WB - ABIN2785760 : Butler, Hanly, Moynagh: Pellino3 is a novel upstream regulator of p38 MAPK and activates CREB in a p38-dependent manner. in The Journal of biological chemistry 2005 (PubMed)

More Antibodies against Pellino E3 Ubiquitin Protein Ligase Family Member 3 Interaction Partners

Mouse (Murine) Pellino E3 Ubiquitin Protein Ligase Family Member 3 (PELI3) interaction partners

  1. Pellino-3 is involved in endotoxin tolerance and functions as a negative regulator of Toll-like receptor 2 (show TLR2 Antibodies)/4 signaling.

  2. autophagy causes PELI3 degradation during TLR4 (show TLR4 Antibodies)-signaling, thereby impairing the hyperinflammatory phase during sepsis by inhibiting proinflammatory IL1B (show IL1B Antibodies) expression

  3. Pellino3 targets RIP1 (show RALBP1 Antibodies) and regulates the pro-apoptotic effects of TNF-alpha (show TNF Antibodies).

  4. Our findings identify RIP2 (show ARHGDIG Antibodies) as a substrate for Pellino3 and Pellino3 as an important mediator in the Nod2 (show NOD2 Antibodies) pathway and regulator of intestinal inflammation.

  5. Pellino3 targets the IRF7 (show IRF7 Antibodies) pathway and facilitates autoregulation of TLR3 (show TLR3 Antibodies)- and viral-induced expression of type I interferons.

Human Pellino E3 Ubiquitin Protein Ligase Family Member 3 (PELI3) interaction partners

  1. Two protective, low-frequency, non-synonymous variants were significantly associated with a decrease in age-related macular degeneration (AMD (show AMD1 Antibodies))risk: A307V in PELI3 and N1050Y in CFH (show CFH Antibodies) .We also identified a strong protective signal for a common variant (rs8056814) near CTRB1 (show CTRB1 Antibodies) associated with a decrease in AMD (show AMD1 Antibodies) risk (logistic regression: OR = 0.71, P = 1.8 x 10-07).

  2. The combination of low Pellino3 levels together with high and inducible Pellino1 expression may be an important determinant of the degree of inflammation triggered upon Toll-like receptor 2 (show TLR2 Antibodies) engagement by Helicobacter pylori and/or its components, contributing to Helicobacter pylori-associated pathogenesis by directing the incoming signal toward an NF-kB-mediated proinflammatory response.

  3. Pellino-3 is involved in endotoxin tolerance and functions as a negative regulator of Toll-like receptor 2 (show TLR2 Antibodies)/4 signaling.

  4. Peptide PEL3 derived from the interleukin-1 receptor-associated kinase (IRAK)1 (show IRAK1 Antibodies)-binding motif reveals a distinct phosphothreonine peptide binding preference.

  5. Our findings identify RIP2 (show ARHGEF28 Antibodies) as a substrate for Pellino3 and Pellino3 as an important mediator in the Nod2 (show NOD2 Antibodies) pathway and regulator of intestinal inflammation.

  6. Pellino3 is a novel upstream regulator of p38 MAPK (show MAPK14 Antibodies) that activates CREB (show CREB1 Antibodies) in a p38 (show CRK Antibodies)-dependent manner

  7. suggest that Pellino 3b acts as a negative regulator for IL-1 (show IL1A Antibodies) signaling by regulating IRAK (show IRAK1 Antibodies) degradation through its ubiquitin protein ligase (show UBE2K Antibodies) activity [Pellino 3b]

Pellino E3 Ubiquitin Protein Ligase Family Member 3 (PELI3) Antigen Profile

Antigen Summary

The protein encoded by this gene is a scaffold protein and an intermediate signaling protein in the innate immune response pathway. The encoded protein helps transmit the immune response signal from Toll-like receptors to IRAK1/TRAF6 complexes. Several transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with Pellino E3 Ubiquitin Protein Ligase Family Member 3 (PELI3)

  • pellino 3 (Peli3) antibody
  • pellino E3 ubiquitin protein ligase family member 3 (PELI3) antibody
  • pellino E3 ubiquitin protein ligase family member 3 (Peli3) antibody
  • pellino homolog 3 (Drosophila) (PELI3) antibody
  • 6030441F14Rik antibody
  • A930011L17 antibody
  • BC028931 antibody
  • RGD1305989 antibody

Protein level used designations for PELI3

E3 ubiquitin-protein ligase pellino homolog 3 , pellino-3 , protein pellino homolog 3 , pellino homolog 3 , pellino 3

GENE ID SPECIES
240518 Mus musculus
246330 Homo sapiens
309157 Rattus norvegicus
483710 Canis lupus familiaris
504839 Bos taurus
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